Search Results - drug+efficacy

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Bi-Directional mTOR Blockade and Companion Biomarkers of Flare and Predictors of Therapeutic Efficacy in SLE
Novel therapeutic intervention targeting mTOR pathways combined with companion biomarkers enables personalized treatment of SLE and its liver complications. Background: Systemic lupus erythematosus (SLE) is a chronic, heterogeneous autoimmune disorder marked by dysregulated immune activity, systemic inflammation, and progressive damage across multiple...
Published: 6/23/2026   |   Updated: 6/23/2026   |   Inventor(s): Andras Perl
Keywords(s): biomarker diagnostics, biomarkers, drug efficacy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Use of Quercetin and Related Flavonoids for the Treatment of Myotonic Dystrophy Types 1 and 2
A novel flavonoids-based therapeutic strategy for the treatment of myotonic dystrophy and potentially repeat expansion disorders. Background: Myotonic dystrophy (DM) is the most common form of adult muscular dystrophy. It is a multisystemic disorder affecting nearly all organs including muscles, brain, heart, eyes, and the GI tract, among others....
Published: 2/13/2026   |   Updated: 10/24/2025   |   Inventor(s): John Berglund, Subodh Mishra, Kaalak Reddy, John Cleary
Keywords(s): drug discovery, drug efficacy, myotonic dystrophy, RNA, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines