Search Results - jia+sheng

4 Results Sort By:
Development of SelU Inhibitors as New Antibiotics
Scientists discovered that special chemical modifications on bacterial tRNA help control protein production and stress responses. They have also developed novel compounds that take advantage of this mechanism to produce antibiotic effects. Background: The field of epitranscriptomics focuses on the chemical modifications of RNA molecules, which are...
Published: 1/29/2026   |   Inventor(s): Jia Sheng, Thomas Begley
Keywords(s): antibiotics, inhibitors, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Drug Design and Synthesis
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 1/29/2026   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Drug Discovery Based on Surface-Enhanced Raman Spectroscopy (SERS)
Enables drug discovery without introducing modifications to the molecules, while lowering costs by requiring only small amounts of the tested molecules. Background: Surface-enhanced Raman spectroscopy (SERS) is a novel, label-free, sensitive, specific, fast, and relatively inexpensive tool for drug discovery. It offers the potential to detect and...
Published: 1/29/2026   |   Inventor(s): Igor Lednev, Lamyaa Almehmadi, Jia Sheng
Keywords(s): Raman spectroscopy, RNA, RNA chemistry, TAF, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Antibodies, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023   |   Inventor(s): Chung-Jen (James) Chou, Ying Mei, Jia Jia
Keywords(s):  
Category(s): BioPharma