Search Results - sriram+neelamegham

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Virus-Like Particles for mRNA Delivery
Virus-like particles have been engineered for drug delivery, gene editing applications, mRNA delivery and overcoming barriers in mouse lungs. Background: Recent biomedical research has shown increased interest in the use of virus-like particles as a drug delivery vehicle. Current viral vectors have been shown to cause adverse immunological responses,...
Published: 5/28/2025   |   Inventor(s): Sriram Neelamegham, Qi Yang
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Gene Therapy, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
Development of Lectins with Protein Engineering
Lectins that exclusively bind sialylated core-2 O-linked glycans within cancerous tissue with a higher affinity than physiologically healthy tissue. Background: Lectins bind complex carbohydrates on cell surfaces and secreted glycoproteins. These carbohydrates are modified during disease from altered metabolism, though the proteins themselves are...
Published: 5/13/2025   |   Inventor(s): Sriram Neelamegham, Ryoma Hombu
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays