Search Results - william+kerr

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A new class of SHIP1 agonists that offer the potential for the development of new treatments for a variety of diseases. Background: An agonist is a drug or substance that binds to a cell receptor, producing the same action as the substance that would naturally bind to the receptor. Agonists form the basis for a wide variety of therapeutics. The...

Published: 5/10/2024 | Inventor(s): William Kerr, Sandra Denney

Keywords(s): Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Artificial Intelligence, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare

Small Molecule Inhibitors for Alzheimer's Immunotherapy

Pan-SHIP1/2 inhibitors enhance phagocytosis of dead neurons and amyloid beta by microglia. Background: The beta-amyloid (1-42) peptide fragment is a crucial component of beta-amyloid debris that forms plaques in Alzheimer's Disease, playing a significant role in disease pathology and cognitive decline. Increased amyloid deposits and tau tangles...

Published: 6/21/2024 | Inventor(s): William Kerr, Chiara Pedicone

Keywords(s): TAF, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines

Biomarker Diagnostic for Crohn's Disease Severity

A novel messenger RNA transcript for prediction of ulcerative colitis and Crohn's disease severity. Background: More than 2 million individuals are diagnosed with Crohn's Disease (CD) and Ulcerative Colitis (UC) in the US every year. While much progress has been made in understanding these diseases, the causes are not fully known and effective...

Published: 2/26/2024 | Inventor(s): William Kerr, Frank Middleton, Sandra Denney

Keywords(s): #SUNYresearch, Technologies

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Campus > Upstate Medical University

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers

Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources

Algorithm for improved Spatial Sampling Design of DNAPL contaminants

SUMMARYImproved algorithm that reduces sampling required to monitor the remediation of Dense Nonaqueous Phase Liquid (DNAPL) contaminants in subsurface water.BACKGROUNDThe difficulties encountered in the remediation of Dense Nonaqueous Phase Liquid (DNAPL) contaminants in the subsurface have spawned numerous studies relating to evaluation of the benefits...

Published: 8/17/2021 | Inventor(s): Linda Abriola, Ke Li

Keywords(s):

Category(s): Software, Cleantech

All-Fiber Multicore Fiber Laser Devices

Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources