Search Results - xiaotian+ji

5 Results Sort By:
Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery
A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity. Background: Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...
Published: 6/21/2024   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines
Injectable Nanogel for Immune Modulation Therapy
A platform for effective therapeutic delivery and immune modulation for effective and quick inflammation control in critical illness, including sepsis. Background: Immune modulation therapy is a type of immunotherapy that enhances the body’s immune regulation and homeostasis. This therapy has proved promising for the treatment of some types...
Published: 7/11/2023   |   Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
2022-085: MULTI-EPITOPE MRNA SARS-COV-2 VACCINE FOR BOOSTING IMMUNITY THROUGH THE ACTIVATION OF CD4 AND CD8 T CELLS AS WELL AS B LYMPHOCYTES
SUMMARY: UCLA Researchers in the Division of Nanomedicine and Microbiology, Immunology and Molecular Genetics have developed a new SARS-CoV-2 vaccine that provides long lasting and robust immunity. BACKGROUND: An effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) constitutes a major global health priority. While multiple...
Published: 3/18/2024   |   Inventor(s): Andre Nel, Tian Xia, Jeffery Miller
Keywords(s):  
Category(s): Therapeutics, Therapeutics > Infectious Diseases, Therapeutics > Vaccines, Therapeutics > Infectious Diseases > COVID
Cross Coupling of Phenolic Derivatives
UC Case No. 2009-085 SUMMARY:Investigators at UCLA have identified a new reaction that enables carbon-carbon bonds and carbon-heteroatom bonds to be introduced into organic molecules. The reaction is cost-effective and highly efficient. BACKGROUND:Synthesis of organic molecules plays a vital role in modern society: carbon-carbon and carbon heteroatom...
Published: 7/19/2023   |   Inventor(s): Neil Garg, Kyle Quasdorf, Xia Tian
Keywords(s):  
Category(s): Chemical > Synthesis, Chemical > Chemical Processing & Manufacturing
2017-176 DEVELOPMENT OF SURFACE ENHANCED GRAPHENE OXIDE FOR UBIQUITOUS ANTIBACTERIAL COATINGS
SummaryUCLA researchers in the Department of Medicine have developed a novel graphene oxide (GO) based material with significantly enhanced antibacterial effects with maximized surface display of carbon radicals.BackgroundAdhesion of bacteria to surfaces of human tissue, biomaterials and medical devices significantly increases the risk of infection...
Published: 7/19/2023   |   Inventor(s): Andre Nel, Tian Xia, Ruibin Li, Mark Hersam, Nikhita Mansukhani, Linda Guiney
Keywords(s): General Device Coatings, Medical Devices and Materials
Category(s): Medical Devices, Medical Devices > Coatings