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Pa
n
creas Cancer Immunotherapy using Cationic Lipid and Polymer Nanocarriers for co-delivery of KRAS Neoantigens and STING or other immunomodulators to boost the Cancer Immunity Cycle and Treat Liver Metastasis (UCLA Case No. 2024-076)
UCLA researchers have developed a tra
n
slational immunotherapy platform that leverages nanoparticle-based delivery of tumor-associated signals and immune-stimulatory molecules to drive localized immune activation in metastatic pancreatic cancer. This approach is designed to initiate de novo immune priming and recondition the tumor microenvironment in...
Published: 10/29/2025
|
Inventor(s):
A
n
dre Nel
Keywords(s):
Category(s):
Therapeutics > O
n
cology
,
Therapeutics > Immu
n
ology And Immunotherapy
,
Therapeutics > Vacci
n
es
,
Platforms > Drug Delivery
N
ovel Adsorbent for Wastewater Treatment and Metal Recovery
I
n
vention Description Heavy metals are non-biodegradable and can contaminate in ecosystems and the food chain, making them one of the most pressing environmental issues of our time. Certain industrial practices have resulted in an increase in the amount of heavy metals discharged into wastewater which can then leach into or contaminate other water...
Published: 10/29/2025
|
Inventor(s):
Elham Fi
n
i
,
Farideh Pahlava
n
Keywords(s):
Category(s):
Adva
n
ced Materials/Nanotechnology
,
E
n
vironmental
,
E
n
vironmental Remediation/Wastewater Treatment
,
Physical Scie
n
ce
U
n
ified Model of Alzheimer’s Disease Pathobiology
I
n
vention Description Understanding of the pathobiology of Alzheimer’s disease (AD) has long been fragmented, with much research centered around biological mechanisms including amyloid β or tau proteins, inflammation, cell death pathways, glia, mitochondria and more. While these all deal with real facets in the biology of AD, they are limited...
Published: 10/29/2025
|
Inventor(s):
Carol Huseby
,
Elai
n
e Delvaux
,
Paul Colema
n
Keywords(s):
Category(s):
Diag
n
ostic Assays/Devices
,
Life Scie
n
ce (All LS Techs)
,
Medical Diag
n
ostics/Sensors
,
N
eurodegenerative Disease Technologies
,
Pharmaceuticals
N
on-Destructive Material Characterization of Crystalline Silicon Solar Photovoltaic Panels
I
n
vention Description Crystalline silicon (c-Si) photovoltaic (PV) panels contain a mix of bulk materials (such as glass, silicon, and aluminum), toxic substances (like lead, tin, and copper), and precious metals. Due to solar panel designs not being standardized, their compositions vary. Panels with lead-based solder, for example, contain more lead...
Published: 10/29/2025
|
Inventor(s):
Dwarak Ravikumar
Keywords(s):
Category(s):
Applied Tech
n
ologies
,
E
n
vironmental
,
Physical Scie
n
ce
,
Ma
n
ufacturing/Construction/Mechanical
Histo
n
e H1 as a Therapeutic Target for Fibrosis (UCLA Case No. 2023-148)
UCLA researchers from the David Geffe
n
School of Medicine have identified linker histone H1 as a critical regulator of pathologic gene expression and cellular mechanics, establishing its potential role as a therapeutic target for the treatment of fibrosis. BACKGROUND: Heart failure affects ~6 million Americans and has a 5-year survival rate of ~50%...
Published: 10/29/2025
|
Inventor(s):
Thomas Vo
n
driska
Keywords(s):
Category(s):
Therapeutics > Cardiovascular
Electro
n
ic-Photonic Quadrature Delay-Locked Oscillator (DLO) For Efficient High-Speed Clock Generation And Distribution
A Quadrature Delay-Locked Oscillator that caters to i
n
creasing multi-GHz and multi-phase clock demands in systems such as time-interleaved architectures. Problem: The unrelenting growth of artificial intelligence (AI) requires advancements in high-performance hardware capable of delivering high-speed clock generation and distribution. These improvements...
Published: 10/29/2025
|
Inventor(s):
Firooz Aflatou
n
i
,
He
n
ry Love
Keywords(s):
Artificial I
n
telligence (AI) & Machine Learning
,
Electro
n
ic Materials
,
Optics & Photo
n
ics
Category(s):
Tech
n
ology Classifications > Computer Information Systems
,
Tech
n
ology Classifications > Hardware & Components
Ready for To
n
sillectomy Mobile App
Applicatio
n
A child-friendly mobile application designed to educate children and caregivers on the purpose of tonsillectomies and guide them through pre-, intra-, and post-operative care using age-appropriate, interactive content. Key Benefits The app is interactive and provides education at a child’s literacy level. Market Summary Tonsillectomies...
Published: 10/29/2025
|
Inventor(s):
Holly Cordray
,
N
ikhila Raol
,
Kara Prickett
Keywords(s):
Healthcare Professio
n
al Education and Training
,
Mobile Apps
,
Pediatrics
Category(s):
TechPub Algolia > Software
Sy
n
thetic Peptide Antigens to Detect Anti-Nephrin Autoantibodies
N
U2025-147 Inventors Jing Jin* Pan Liu Short Description The invention provides a method for detecting anti-nephrin autoantibodies implicated in kidney diseases like minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS). This method employs synthetic peptide antigens for use as a clinical diagnostic. Background Kidney...
Published: 10/28/2025
|
Inventor(s):
Keywords(s):
Category(s):
Life Scie
n
ces > Biomarkers & Biomedical Research Tools
Precisio
n
DNA PCR-based Assay for Gardnerella vaginalis species in bacterial vaginosis
PAGE TITLE Overview PAGE SUMMARY This
n
ew PCR-based companion diagnostic assay leverages genetic analysis to identify specific members of the Gardnerella vaginalis species and detects resistance to metronidazole, the current first-line treatment for bacterial vaginosis (BV). BV is a prevalent vaginal infection with ~30% annual incidence, high recurrence...
Published: 10/28/2025
|
Inventor(s):
Garth Ehrlich
,
Katheri
n
e Innamorati
,
Joshua Earl
Keywords(s):
Category(s):
Medical Devices, Diag
n
ostics & Biosensors
Highly-Se
n
sitive Point-of-Care Diagnostics & Disease Monitoring
Descriptio
n
This technology is a novel, highly-sensitive platform to diagnose and monitor diseases in real time at a doctor’s office. Many chronic diseases like cancer and IBD do not have initial screening tests and solely rely on invasive, uncomfortable and time-consuming procedures (like biopsies and colonoscopies). Having a less invasive...
Published: 10/28/2025
|
Inventor(s):
A. G. U
n
il Perera
,
Mathes Daya
n
anda
,
Heme
n
dra Ghimire
,
Mehmood Piarzada
Keywords(s):
Category(s):
Assay
,
Device
,
Diag
n
ostic
,
Imagi
n
g
,
Research Tool
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