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ID
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A desig
n
to manufacture polyamide reverse osmosis membrane using molecular layer-by-layer deposition
Thi
n
-film composite polyamide membranes, are the basis for modern commercial reverse osmosis (RO) membranes. These membranes are created through interfacial polymerization (IP) involving a trifunctional acid chloride (e.g., trimesoyl chloride, TMC, dissolved in an organic solvent) and a difunctional amine (e.g., m-phenylenediamine, MPD, dissolved in...
Published: 5/30/2025
|
Inventor(s):
Samarpa
n
Deb Majumder
,
Xito
n
g Liu
Keywords(s):
Category(s):
Tech
n
ology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
,
Tech
n
ology Classifications > Industrial or Consumer Tech > Industrial Manufacturing
Robot-Aided System A
n
d Method For Diagnosis Of Autism Spectrum Disorder
Se
n
sory abnormalities are reported to be central to autistic experience. The symptoms include hyposensitivity, hypersensitivity, multichannel receptivity, processing difficulties and sensory overload. Given the intensive and cumbersome nature of current methods of diagnosis, there is a need of behavior-based approach to identify the children at risk...
Published: 5/30/2025
|
Inventor(s):
Chu
n
g Hyuk Park
,
Hifza Javed
Keywords(s):
Category(s):
Tech
n
ology Classifications > Diagnostics
,
Tech
n
ology Classifications > Medical Devices > Therapeutic Devices
Tampa
N
euromapping Depth Electrode
Adva
n
tages Combines recording and stimulation in a single device Reduces brain penetration and surgery time Lowers risk of hemorrhage, infection, and brain shift Enables precise brain mapping and real-time stimulation Summary Deep Brain Stimulation (DBS) helps patients with movement disorders like Parkinson’s disease by sending electrical...
Published: 5/30/2025
|
Inventor(s):
Oliver Flouty
,
Yarema Bezchlib
n
yk
,
Vishal Bharmauria
,
N
our Shaheen
,
Bria
n
Dalm
,
Ca
n
Sarica
,
Matthew Howard
,
Hiroto Kawasaki
,
Mario Za
n
aty
,
Alex Gree
n
,
A
n
dres Lozano
Keywords(s):
Category(s):
Tech
n
ology Classifications > Medical > Neuroscience
E
n
gineering Asymmetrically Glycosylated IgG Antibodies
Applicatio
n
A novel method to develop asymmetrically glycosylated therapeutic monoclonal IgG antibodies for preventing and treating diseases like cancer, infectious diseases, and autoimmune disorders. Key Benefits Different IgG antibody glycoforms can be produced, each with its unique effector functions and biological and therapeutic effects. Potential...
Published: 5/30/2025
|
Inventor(s):
Eric J. Su
n
dberg
,
Jo
n
athan Du
,
Tala Azzam
Keywords(s):
A
n
tibodies
,
Immu
n
ology and Inflammation Treatments
,
Microbiology a
n
d Infectious Disease Treatments
,
O
n
cology Treatments
Category(s):
TechPub Algolia > Therapeutics
Compa
n
ion Diagnostic for Immunomodulatory Repair Treatments
This tech
n
ology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
|
Inventor(s):
Steve
n
Goldman
,
Da
n
iel Benson
,
Adria
n
Grijalva
,
Jorda
n
Fink
,
Jorda
n
Lancaster
,
Je
n
nifer Koevary
,
Simar Si
n
gh
Keywords(s):
Category(s):
Tech
n
ology Classifications > Life Sciences > Diagnostics
,
Tech
n
ology Classifications > Research Tools > Screening assays
,
Tech
n
ology Classifications > Healthcare Portfolios > Heart and Vascular
R
N
A Binding Motif 3 (RBM3) Overexpressing Transgenic Mouse
Adva
n
tages • RBM3 upregulation reverses multiple tau phosphorylations post-TBI • Novel RBM3 Overexpressing Transgenic Mouse Model allows researchers to study the effects of RBM3 activation on tissue function, brain function, and brain injury Summary Traumatic brain injury (TBI) not only causes immediate neuronal damage but also...
Published: 5/30/2025
|
Inventor(s):
Travis Jackso
n
Keywords(s):
A
n
imal Models
,
N
euroscience
Category(s):
Tech
n
ology Classifications > Research Tools/Copyright > Animal Models
,
Tech
n
ology Classifications > Medical > Neuroscience
,
Tech
n
ology Classifications > Medical > Biotechnology
Method for Co-Localizi
n
g Two Proteins on the Inside of the Cell Membrane in Yeast
Adva
n
tages Localization of protein interactions at the cell membrane offers a more physiologically relevant model Improved screening by minimizing off-target interactions Broadly applicable and accessible tools Summary Protein-protein interactions involving membrane proteins are notoriously difficult to study under physiologically relevant conditions....
Published: 5/30/2025
|
Inventor(s):
Lawre
n
ce Stern
,
Michael
N
elson
Keywords(s):
Drug Discovery
Category(s):
Tech
n
ology Classifications > Medical > Cell & Tissue Engineering
,
Tech
n
ology Classifications > Medical > Medical Diagnostics
,
Tech
n
ology Classifications > Medical > Biomaterials
Tra
n
sgenic Foxc2-tdTomato Overexpressing Mouse Model for Study and Screening of Lymphatic Valve Development
Adva
n
tages Tissue specific Foxc2 expression with integrated tdTomato fluorescent reporter enables precise spatiotemporal visualization Enables monitoring of lymphatic valve development 1:1 co-expression of Foxc2 and tdTomato, overcoming expression variability characteristic associated with of IRES-based or viral delivery systems Single-vector...
Published: 5/30/2025
|
Inventor(s):
Joshua Scalla
n
Keywords(s):
A
n
imal Models
Category(s):
Tech
n
ology Classifications > Research Tools/Copyright > Animal Models
Sy
n
thesis of Non-steroidal Anti-Inflammatory Compounds to Promote Wound Healing
Graph shows the average ski
n
punch biopsy weight of mice treated topically with nitrogen mustard (NM) to induce skin inflammation. Mice additionally treated with polyamine-imidazole conjugates showed a marked decrease in skin inflammation. Invention Summary: Non-steroidal Anti-Inflammatory drugs (NSAIDs) are widely available for over-the-counter...
Published: 5/30/2025
|
Inventor(s):
Jeffrey Laski
n
,
N
ed Heindel
,
Christophe Guillo
n
Keywords(s):
Category(s):
Tech
n
ology Classifications > Therapeutics
,
Tech
n
ology Classifications > Healthcare & Life Sciences
Repurposed Receptor Blocker for the Treatme
n
t of PTSD
Applicatio
n
Use of neurokinin 3 receptor antagonist, osanetant, for the prevention and treatment of post-traumatic stress disorder (PTSD) and other anxiety disorders. Key Benefits Utilizes a repurposed drug that is safe for human use. Potential to treat specific PTSD symptoms better than antidepressants. Market Summary Post-traumatic stress...
Published: 5/30/2025
|
Inventor(s):
Kerry Ressler
,
Raul A
n
dero Gali
Keywords(s):
N
eurology and Pain Treatments
,
Repurposed Drug
Category(s):
TechPub Algolia > Therapeutics
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