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ID
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Method for Repurposi
n
g FDA-approved Therapeutics & Composition for Treating Mesothelioma
The amou
n
t of time and money that goes into getting a drug from initial discovery to FDA approval is substantial, typically involving at least 10 years and hundreds of millions of dollars. Because of this, there has been a growing interest in repurposing drugs which have previously been approved for human use, particularly since their MOA as well as...
Published: 1/8/2025
|
Inventor(s):
Chris Plaisier
,
Sierra Wilferd
,
Chou
n
g Hoang
Keywords(s):
Ca
n
cer
,
Drug
,
Drug Discovery
Category(s):
Pharmaceuticals
,
Ca
n
cer
,
Ca
n
cer Therapeutics
,
Artificial I
n
telligence/Machine Learning
,
Computi
n
g & Information Technology
,
Life Scie
n
ce (All LS Techs)
Modified Simmo
n
s Catheter
N
eurointerventions with improved success Invention Summary: The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 1/8/2025
|
Inventor(s):
Amit Si
n
gla
Keywords(s):
N
eurological disorder & neuropathic pain
Category(s):
Tech
n
ology Classifications > Diagnostics
,
Tech
n
ology Classifications > Healthcare & Life Sciences
,
Tech
n
ology Classifications > Medical Devices
A
n
tibacterial Coagulating Gel Spray
Blood loss a
n
d infections are a major cause of concern and death for traumatic injuries and wounds. It is estimated that blood loss accounts for more than 35% of all prehospital deaths in trauma patients. Thus, it is imperative that bleeding is stopped quickly and at the point of care. While there are many products to staunch bleeding, including gauze...
Published: 1/8/2025
|
Inventor(s):
Emily Byr
n
e
,
Grace Billi
n
gsley
,
Tra
n
Nguyen
,
Alfo
n
so Gomez-De Leon
,
Oscar Voeller
,
Sarah Stabe
n
feldt
,
Jessica Weaver
Keywords(s):
Category(s):
Adva
n
ced Materials/Nanotechnology
,
Biomaterials
,
Life Scie
n
ce (All LS Techs)
,
Medical Devices
Selective Modulators of Ah-R to Treat Ca
n
cer
Sy
n
ergistic compositions and method of using modulators of Ah-R activity and synergistic compounds to treat cancer Background Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. When activated by the binding of a wide range of both endogenous and exogenous small molecules, AhR signaling influences cellular outcomes in different...
Published: 1/8/2025
|
Inventor(s):
Siva Kolluri
,
Bach
N
guyen
,
Da
n
iel Elson
Keywords(s):
Category(s):
Therapeutics
Pharmaceutical ma
n
ufacturing of the future: a continuous 3D printing approach for personalized medicine
Backgrou
n
d Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharmaceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
Published: 1/8/2025
|
Inventor(s):
Mohammed Ma
n
iruzzaman
,
Vi
n
eet Kulkarni
,
Faez Alkadi
Keywords(s):
Category(s):
Life scie
n
ces > Therapeutics > Manufacturing platform
Laser apparatus for micro-volume tissue excisio
n
This tech
n
ology uses a laser to remove tiny pieces of tissue for analysis. The laser is shaped into a ring and can be combined with cooling techniques to minimize damage. Background The traditional histopathology workflow, while considered the gold standard for tissue diagnosis, suffers from several limitations. These include the invasiveness of biopsies,...
Published: 1/8/2025
|
Inventor(s):
Thomas Mil
n
er
,
James Tu
n
nell
,
Jaso
n
King
,
N
itesh Katta
Keywords(s):
Category(s):
Life scie
n
ces > Medical technology > Medical devices
,
Life scie
n
ces > Medical technology
Highly se
n
sitive pressure sensor for diverse applications
A flexible, highly se
n
sitive pressure sensor combines resistive and capacitive elements using a porous carbon nanotube–Eco flex material. It accurately detects a wide range of pressures, is easy to fabricate, and suits diverse applications like medical monitoring and environmental sensing. Background Pressure sensing technology plays a crucial...
Published: 1/8/2025
|
Inventor(s):
N
anshu Lu
,
Kyou
n
g-Ho Ha
Keywords(s):
Category(s):
Life scie
n
ces > Medical technology
Auto
n
omous Brain Machine Interface
A
n
advanced system that enables patients to better control prosthetic devices. Background: Many pathologies lead to loss of the ability to use one or more limbs. Historically, the lost or damaged limb is replaced with a prosthetic device. In recent years prosthetic technology has been developed to enable the control of these devices via a neural signal...
Published: 1/7/2025
|
Inventor(s):
Joseph Fra
n
cis
,
Ve
n
kata S. Aditya Tarigoppula
,
Bra
n
di Marsh
Keywords(s):
Category(s):
Campus > SU
N
Y Downstate Health Sciences University
,
Tech
n
ology Classifications > Computers
I
n
tramedullary Temporomandibular Joint (TMJ) Implant
A
n
ovel TMJ implant that reduces stress and strain on the patient. Background: The temporomandibular joint (TMJ) is involved in functions such as chewing, swallowing, and speaking. Degenerative disorders of the TMJ are typically treated with anti-inflammatory drugs. However, once the TMJ has been compromised, surgical treatment is commonly performed....
Published: 1/7/2025
|
Inventor(s):
Marti
n
Pendola
Keywords(s):
Category(s):
Campus > SU
N
Y Downstate Health Sciences University
,
Tech
n
ology Classifications > Medical Devices
Ca
n
cer treatment through hTERT inhibition
Title: Ca
n
cer Treatment Through hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...
Published: 1/7/2025
|
Inventor(s):
Laure
n
ce Hurley
,
Vijay Gokhale
,
Hyu
n
Jin Kang
,
Kui Wu
Keywords(s):
Category(s):
Tech
n
ology Classifications > Healthcare Portfolios > Oncology
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