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ID
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Meth
o
d for Repurposing FDA-approved Therapeutics & Composition for Treating Mesothelioma
The am
o
unt of time and money that goes into getting a drug from initial discovery to FDA approval is substantial, typically involving at least 10 years and hundreds of millions of dollars. Because of this, there has been a growing interest in repurposing drugs which have previously been approved for human use, particularly since their MOA as well as...
Published: 1/8/2025
|
Inventor(s):
Chris Plaisier
,
Sierra Wilferd
,
Ch
o
ung Hoang
Keywords(s):
Cancer
,
Drug
,
Drug Disc
o
very
Category(s):
Pharmaceuticals
,
Cancer
,
Cancer Therapeutics
,
Artificial Intelligence/Machine Learning
,
C
o
mputing & Information Technology
,
Life Science (All LS Techs)
M
o
dified Simmons Catheter
Neur
o
interventions with improved success Invention Summary: The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 1/8/2025
|
Inventor(s):
Amit Singla
Keywords(s):
Neur
o
logical disorder & neuropathic pain
Category(s):
Techn
o
logy Classifications > Diagnostics
,
Techn
o
logy Classifications > Healthcare & Life Sciences
,
Techn
o
logy Classifications > Medical Devices
Antibacterial C
o
agulating Gel Spray
Bl
o
od loss and infections are a major cause of concern and death for traumatic injuries and wounds. It is estimated that blood loss accounts for more than 35% of all prehospital deaths in trauma patients. Thus, it is imperative that bleeding is stopped quickly and at the point of care. While there are many products to staunch bleeding, including gauze...
Published: 1/8/2025
|
Inventor(s):
Emily Byrne
,
Grace Billingsley
,
Tran Nguyen
,
Alf
o
nso Gomez-De Leon
,
O
scar Voeller
,
Sarah Stabenfeldt
,
Jessica Weaver
Keywords(s):
Category(s):
Advanced Materials/Nan
o
technology
,
Bi
o
materials
,
Life Science (All LS Techs)
,
Medical Devices
Selective M
o
dulators of Ah-R to Treat Cancer
Synergistic c
o
mpositions and method of using modulators of Ah-R activity and synergistic compounds to treat cancer Background Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. When activated by the binding of a wide range of both endogenous and exogenous small molecules, AhR signaling influences cellular outcomes in different...
Published: 1/8/2025
|
Inventor(s):
Siva K
o
lluri
,
Bach Nguyen
,
Daniel Els
o
n
Keywords(s):
Category(s):
Therapeutics
Pharmaceutical manufacturing
o
f the future: a continuous 3D printing approach for personalized medicine
Backgr
o
und Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharmaceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
Published: 1/8/2025
|
Inventor(s):
M
o
hammed Maniruzzaman
,
Vineet Kulkarni
,
Faez Alkadi
Keywords(s):
Category(s):
Life sciences > Therapeutics > Manufacturing platf
o
rm
Laser apparatus f
o
r micro-volume tissue excision
This techn
o
logy uses a laser to remove tiny pieces of tissue for analysis. The laser is shaped into a ring and can be combined with cooling techniques to minimize damage. Background The traditional histopathology workflow, while considered the gold standard for tissue diagnosis, suffers from several limitations. These include the invasiveness of biopsies,...
Published: 1/8/2025
|
Inventor(s):
Th
o
mas Milner
,
James Tunnell
,
Jas
o
n King
,
Nitesh Katta
Keywords(s):
Category(s):
Life sciences > Medical techn
o
logy > Medical devices
,
Life sciences > Medical techn
o
logy
Highly sensitive pressure sens
o
r for diverse applications
A flexible, highly sensitive pressure sens
o
r combines resistive and capacitive elements using a porous carbon nanotube–Eco flex material. It accurately detects a wide range of pressures, is easy to fabricate, and suits diverse applications like medical monitoring and environmental sensing. Background Pressure sensing technology plays a crucial...
Published: 1/8/2025
|
Inventor(s):
Nanshu Lu
,
Ky
o
ung-Ho Ha
Keywords(s):
Category(s):
Life sciences > Medical techn
o
logy
Aut
o
nomous Brain Machine Interface
An advanced system that enables patients t
o
better control prosthetic devices. Background: Many pathologies lead to loss of the ability to use one or more limbs. Historically, the lost or damaged limb is replaced with a prosthetic device. In recent years prosthetic technology has been developed to enable the control of these devices via a neural signal...
Published: 1/7/2025
|
Inventor(s):
J
o
seph Francis
,
Venkata S. Aditya Tarig
o
ppula
,
Brandi Marsh
Keywords(s):
Category(s):
Campus > SUNY D
o
wnstate Health Sciences University
,
Techn
o
logy Classifications > Computers
Intramedullary Temp
o
romandibular Joint (TMJ) Implant
A n
o
vel TMJ implant that reduces stress and strain on the patient. Background: The temporomandibular joint (TMJ) is involved in functions such as chewing, swallowing, and speaking. Degenerative disorders of the TMJ are typically treated with anti-inflammatory drugs. However, once the TMJ has been compromised, surgical treatment is commonly performed....
Published: 1/7/2025
|
Inventor(s):
Martin Pend
o
la
Keywords(s):
Category(s):
Campus > SUNY D
o
wnstate Health Sciences University
,
Techn
o
logy Classifications > Medical Devices
Cancer treatment thr
o
ugh hTERT inhibition
Title: Cancer Treatment Thr
o
ugh hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...
Published: 1/7/2025
|
Inventor(s):
Laurence Hurley
,
Vijay G
o
khale
,
HyunJin Kang
,
Kui Wu
Keywords(s):
Category(s):
Techn
o
logy Classifications > Healthcare Portfolios > Oncology
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