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ID
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Meth
o
d of Treating Obesity-Induced Glucose Intolerance and Liver Fibrosis (UCLA Case No. 2021-323)
UCLA researchers in the Sch
o
ol of Engineering have discovered a novel method to treat obesity-induced glucose intolerance and liver fibrosis. BACKGROUND: The CDC reports that 41.9% of adults ages 20 and over are obese. An increased incidence of obesity also increases the rates of comorbidities such at type 2 diabetes mellitus (T2DM), non-alcoholic...
Published: 9/24/2024
|
Inventor(s):
Zhen Gu
Keywords(s):
gluc
o
se intolerance
,
liver fibr
o
sis
,
Nan
o
particles
,
N
o
tch signaling pathway
,
o
besity
Category(s):
Therapeutics > Metab
o
lism And Endocrinology
SELECTIVE SENSITIZATI
O
N OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES
SELECTIVE SENSITIZATI
O
N OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES Researchers at Stanford University have developed a novel method for the treatment and prevention of cancer. The immune system is an integral part of the human body’s response to outside threats, including cancer. Specifically, cytotoxic CD8+ T cells have been...
Published: 9/24/2024
|
Inventor(s):
Reece Akana
Keywords(s):
Cancer
,
Immun
o
-Oncology
,
T-Cell Activati
o
n
Category(s):
Techn
o
logy Classifications > Biology
C
O
MPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
C
O
MPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
|
Inventor(s):
Charles Chan
,
Th
o
mas Ambrosi
,
Irving Weissman
,
Michael L
o
ngaker
,
Rahul Sinha
,
Debashis Sah
o
o
Keywords(s):
Hydr
o
gel
,
Stem Cell
Category(s):
Techn
o
logy Classifications > Biology
DESIGN
O
F UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN
O
F UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford University have developed novel universal vaccine candidates for H5 influenza viruses. Influenza remains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
|
Inventor(s):
Du
o
Xu
,
Peter Kim
Keywords(s):
Immun
o
focusing
,
Vaccine
Category(s):
Techn
o
logy Classifications > Biology
N
O
VEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
N
O
VEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose. Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024
|
Inventor(s):
Evan
O
brien
,
Kaavya Kumar
,
Brian K
o
bilka
,
Susruta Majumdar
,
Vipin Rangari
Keywords(s):
O
piod
,
Pain
Category(s):
Techn
o
logy Classifications > Chemistry
C41 Anal
o
gs
This inventi
o
n relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
|
Inventor(s):
Wei Wang
,
Rui Chang
,
Vijayan Ramachandran
,
Patrick R
o
naldson
Keywords(s):
Category(s):
Techn
o
logy Classifications > Healthcare Portfolios > Neurology
,
Techn
o
logy Classifications > Life Sciences > Nutraceuticals
,
Techn
o
logy Classifications > Life Sciences > Small Molecules
,
Techn
o
logy Classifications > Life Sciences > Therapeutics
,
Techn
o
logy Classifications > Life Sciences > Biologics
Stimulati
o
n Device to treat Hand Weakness from Stroke or Spinal Injury
A gr
o
wing number of people experience hand weakness due to stroke or spinal cord injuries. Electrical stimulation (e-stim) devices are commonly used to assist in hand weakness therapy. However, they are bulky, expensive, uncomfortable (may be ill-fitting, cause skin irritation or unpleasant sensation), and non-portable, eliminating the potential for...
Published: 9/24/2024
|
Inventor(s):
Atharva Wani
,
Niteesh Nigam
,
O
nkar Chavan
,
Yash Bellap
,
J
o
elly Lobato
,
Ishan Swanand Vyas
,
Suhrud Parag J
o
glekar
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Medical Devices
,
Manufacturing/C
o
nstruction/Mechanical
Vital Signs M
o
nitoring using Depth Cameras
Cardi
o
vascular disease is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 9/24/2024
|
Inventor(s):
Yu R
o
ng
,
Daniel Bliss
Keywords(s):
Category(s):
C
o
mputing & Information Technology
,
Medical Devices
,
Life Science (All LS Techs)
,
Medical Diagn
o
stics/Sensors
,
Medical Imaging
Head M
o
tion Correction with Soft Pressure Pad for MRI Scans
Addressed Need Head m
o
tion remains a major challenge during medical imaging scans, particularly in pediatric and older patient populations. Motion impacts diagnostic image quality, costing both time and money in the clinical setting. In research, motion artifacts can introduce errors into quantitative measurements, especially in high-resolution or...
Published: 9/24/2024
|
Inventor(s):
Keywords(s):
Category(s):
Medical Devices
,
Medical Imaging
Inhibit
o
rs of the N-terminal Domain of the Androgen Receptor (UCLA Case No. 2023-075)
Researchers at UCLA under the guidance
o
f Drs. Matthew Rettig and Michael Jung have developed novel molecular compounds that reduce growth of prostate cancer cells. Dr. Jung in collaboration with Dr. Rettig have furthered the development of these compounds by synthesizing a new series of analogues that have similar inhibitory effects. BACKGROUND: Prostate...
Published: 9/23/2024
|
Inventor(s):
Matthew Rettig
,
Michael Jung
Keywords(s):
andr
o
gen receptor therapy
,
castrati
o
n resistant prostate cancer
,
O
ncology
,
O
ncology (Small Molecules, Peptides and Antibodies)
,
pr
o
state cancer
,
small m
o
lecules
Category(s):
Therapeutics >
O
ncology
,
Therapeutics >
O
ncology > Oncology (Small Molecules)
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3
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8
9
10
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