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M
ethod of Treating Obesity-Induced Glucose Intolerance and Liver Fibrosis (UCLA Case No. 2021-323)
UCLA researchers in the School of Engineering have discovered a novel
m
ethod to treat obesity-induced glucose intolerance and liver fibrosis. BACKGROUND: The CDC reports that 41.9% of adults ages 20 and over are obese. An increased incidence of obesity also increases the rates of comorbidities such at type 2 diabetes mellitus (T2DM), non-alcoholic...
Published: 9/24/2024
|
Inventor(s):
Zhen Gu
Keywords(s):
glucose intolerance
,
liver fibrosis
,
Nanoparticles
,
Notch signaling pathway
,
obesity
Category(s):
Therapeutics >
M
etabolism And Endocrinology
SELECTIVE SENSITIZATION OF CANCER CELLS TO ELI
M
INATION BY CYTOTOXIC LYMPHOCYTES
SELECTIVE SENSITIZATION OF CANCER CELLS TO ELI
M
INATION BY CYTOTOXIC LYMPHOCYTES Researchers at Stanford University have developed a novel method for the treatment and prevention of cancer. The immune system is an integral part of the human body’s response to outside threats, including cancer. Specifically, cytotoxic CD8+ T cells have been...
Published: 9/24/2024
|
Inventor(s):
Reece Akana
Keywords(s):
Cancer
,
I
m
muno-Oncology
,
T-Cell Activation
Category(s):
Technology Classifications > Biology
CO
M
POSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
CO
M
POSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
|
Inventor(s):
Charles Chan
,
Tho
m
as Ambrosi
,
Irving Weiss
m
an
,
M
ichael Longaker
,
Rahul Sinha
,
Debashis Sahoo
Keywords(s):
Hydrogel
,
Ste
m
Cell
Category(s):
Technology Classifications > Biology
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford University have developed novel universal vaccine candidates for H5 influenza viruses. Influenza re
m
ains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
|
Inventor(s):
Duo Xu
,
Peter Ki
m
Keywords(s):
I
m
munofocusing
,
Vaccine
Category(s):
Technology Classifications > Biology
NOVEL S
M
ALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
NOVEL S
M
ALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose. Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024
|
Inventor(s):
Evan Obrien
,
Kaavya Ku
m
ar
,
Brian Kobilka
,
Susruta
M
ajumdar
,
Vipin Rangari
Keywords(s):
Opiod
,
Pain
Category(s):
Technology Classifications > Che
m
istry
C41 Analogs
This invention relates generally to neurodegenerative diseases and conditions, such as Alzhei
m
er’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
|
Inventor(s):
Wei Wang
,
Rui Chang
,
Vijayan Ra
m
achandran
,
Patrick Ronaldson
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Neurology
,
Technology Classifications > Life Sciences > Nutraceuticals
,
Technology Classifications > Life Sciences > S
m
all Molecules
,
Technology Classifications > Life Sciences > Therapeutics
,
Technology Classifications > Life Sciences > Biologics
Sti
m
ulation Device to treat Hand Weakness from Stroke or Spinal Injury
A growing nu
m
ber of people experience hand weakness due to stroke or spinal cord injuries. Electrical stimulation (e-stim) devices are commonly used to assist in hand weakness therapy. However, they are bulky, expensive, uncomfortable (may be ill-fitting, cause skin irritation or unpleasant sensation), and non-portable, eliminating the potential for...
Published: 9/24/2024
|
Inventor(s):
Atharva Wani
,
Niteesh Niga
m
,
Onkar Chavan
,
Yash Bellap
,
Joelly Lobato
,
Ishan Swanand Vyas
,
Suhrud Parag Joglekar
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
M
edical Devices
,
M
anufacturing/Construction/Mechanical
Vital Signs
M
onitoring using Depth Cameras
Cardiovascular disease is responsible for an esti
m
ated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 9/24/2024
|
Inventor(s):
Yu Rong
,
Daniel Bliss
Keywords(s):
Category(s):
Co
m
puting & Information Technology
,
M
edical Devices
,
Life Science (All LS Techs)
,
M
edical Diagnostics/Sensors
,
M
edical Imaging
Head
M
otion Correction with Soft Pressure Pad for MRI Scans
Addressed Need Head
m
otion remains a major challenge during medical imaging scans, particularly in pediatric and older patient populations. Motion impacts diagnostic image quality, costing both time and money in the clinical setting. In research, motion artifacts can introduce errors into quantitative measurements, especially in high-resolution or...
Published: 9/24/2024
|
Inventor(s):
Keywords(s):
Category(s):
M
edical Devices
,
M
edical Imaging
Inhibitors of the N-ter
m
inal Domain of the Androgen Receptor (UCLA Case No. 2023-075)
Researchers at UCLA under the guidance of Drs.
M
atthew Rettig and Michael Jung have developed novel molecular compounds that reduce growth of prostate cancer cells. Dr. Jung in collaboration with Dr. Rettig have furthered the development of these compounds by synthesizing a new series of analogues that have similar inhibitory effects. BACKGROUND: Prostate...
Published: 9/23/2024
|
Inventor(s):
M
atthew Rettig
,
M
ichael Jung
Keywords(s):
androgen receptor therapy
,
castration resistant prostate cancer
,
Oncology
,
Oncology (S
m
all Molecules, Peptides and Antibodies)
,
prostate cancer
,
s
m
all molecules
Category(s):
Therapeutics > Oncology
,
Therapeutics > Oncology > Oncology (S
m
all Molecules)
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