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Search Results - young-sup+yoon
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HDAC Inhibitors for Managing Vascular Conditions and Diabetic Peripheral Neuropathies
Application Treatment of diabetic neuropathy using epigenetic modulators, histone deacetylase inhibitors (HDACis), to ameliorate or prevent vascular conditions and neuropathic pains by nerve damages. Key Benefits Reverses or protects against diabetes-induced nerve damages by direct injection of HDACi. Relatively low regulatory risk because many...
Published: 10/28/2024
|
Inventor(s):
Young-Sup Yoon
,
Ji Woong (Jay) Han
,
Hyunsuk Shim
Keywords(s):
Cell/Gene Therapy
,
Endocrinology
,
Metabolic Diseases
,
Repurposed Drug
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
Reprogramming of Fibroblasts toward a Three-Dimensional Vascularized Cardiomimetic Tissue (CMT)
Application Fibroblasts reprogrammed into tissue-like patch including functional cardiomyocyte, endothelial, smooth muscle and pericyte cells for treatment of cardiac diseases. Key Benefits Enables simultaneous reprogramming of multi-lineage cells including cardiomyocytes and endothelial cells Increases expression of cardioprotective paracrine...
Published: 7/30/2024
|
Inventor(s):
Young-Sup Yoon
,
Jaeyeaon Cho
Keywords(s):
Cardiovascular
,
Cell/Gene Therapy
,
Platform
,
Regenerative Medicine
Category(s):
TechPub Algolia > Therapeutics
Purification of Specific Cell Types from Stem Cells via Fluorescent Probes
Application Dual-labeled antisense oligonucleotide probes for fluorescent activated cell sorting (FACS) of pluripotent stem cells. Key Benefits Allows for the purification of a homogeneous cell population compared to currently available techniques which can only produce heterogeneous mixtures. Binds intracellular RNA using standard delivery techniques...
Published: 7/30/2024
|
Inventor(s):
Young-Sup Yoon
,
Kiwon Ban
,
Brian Wile
,
Gang Bao
Keywords(s):
Cell/Gene Therapy
Category(s):
TechPub Algolia > Research Tools
,
TechPub Algolia > Therapeutics
Functional Restoration of Diabetic Bone Marrow-Derived Cells
Application Methods for restoration of diabetic bone marrow cell function for cell based therapy, using pre-existing molecules and their derivatives. Key Benefits Ability to "reactivate" diabetic bone marrow-derived stem or progenitor cells which also include peripheral blood cells such as endothelial progenitor cells. Cells are more...
Published: 7/30/2024
|
Inventor(s):
Young-Sup Yoon
,
Ji Woong (Jay) Han
Keywords(s):
Cell/Gene Therapy
,
Metabolic Diseases
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
Chemically Induced Pluripotent Stem (CiPS) Cells
Application Generation of pluripotent stem cells from adult somatic cells for medical use. Key Benefits No exogenous genetic manipulations, which minimize oncogenic effects, were observed in current methods. Peripheral blood can be used as a source of parent cell instead of fibroblasts or keratinocytes. Market Summary The economic and psychological...
Published: 7/30/2024
|
Inventor(s):
Young-Sup Yoon
,
Ji Woong (Jay) Han
,
Xiaodong Cheng
,
Antonello Mai
Keywords(s):
Cell Line
,
Cell/Gene Therapy
Category(s):
TechPub Algolia > Therapeutics
Device and Kit Isolate Vasculogenic Cells from Blood
Application A device and kit for isolating therapeutic quantities of vasculgenic cells from blood that acts as an autologous adult stem cell therapy for the treatment of limb ischemia, ischemic heart disease, and other vascular-related disorders. Key Benefits Reduces complexity and expense of current autologous stem cell therapies. Cells can be...
Published: 10/28/2024
|
Inventor(s):
Young-Sup Yoon
,
Hyun-Jai Cho
Keywords(s):
Cardiovascular
,
Cell/Gene Therapy
,
Regenerative Medicine
Category(s):
TechPub Algolia > Therapeutics