Search Results - john+david+lambeth

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Novel Inhibitors of NOX2/ROS
Applications Novel therapeutics for treatment of various inflammatory airway conditions including chronic obstructive pulmonary disease (COPD). Key Benefits NOX2/ROS inhibitors have potential for use in a wide variety of clinical indications. Current treatments are weakly effective or provide only symptomatic relief for inflammatory airway diseases. Technical...
Published: 7/30/2024   |   Inventor(s): Thota Ganesh, John David Lambeth, Susan Smith, Aiming Sun
Keywords(s): Cardiovascular, Immunology/Inflammation, Metabolic Diseases, Neuroscience/Pain, Respiratory, Small Molecule
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Nox cDNA and Enzymes for Drug Discovery, for Diagnostics, and as Research Tools
Application Target for drug discovery, gene therapy and to create a diagnostic tool relevant to conditions involving inappropriate cell proliferation. Technical Summary Reactive oxygen species (ROS) include superoxide and hydrogen peroxide. ROS are increasingly being recognized as playing a central role in diverse physiologic and pathologic processes....
Published: 11/20/2024   |   Inventor(s): John David Lambeth, Guang Cheng
Keywords(s): Cardiovascular, Enzyme/Protein, Immunology/Inflammation, Oncology, Target
Category(s): TechPub Algolia > Research Tools
Mitogenic Oxygenase Regulators for Drug Discovery
Applications Can be used as a target for drug discovery, gene therapy and, to create a diagnostic tool. These applications are relevant to conditions involving inappropriate cell proliferation (e.g., cancer, atherosclerosis), angiogenesis, and tissue damage associated with inflammatory diseases. Technical Summary Reactive oxygen species (ROS) include...
Published: 12/4/2024   |   Inventor(s): John David Lambeth, Guang Cheng
Keywords(s): Cardiovascular, Enzyme/Protein, Immunology/Inflammation, Oncology, Target
Category(s): TechPub Algolia > Drug Discovery