Search Results - lee+lee

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Inorganic Ion Eluting Nanoparticulate Mineralized Collagen Glycosaminoglycan Materials (UCLA Case No. 2023-140)
UCLA researchers from the Division of Plastic and Reconstructive Surgery at the UCLA David Geffen School of Medicine have developed an innovative inorganic ion-eluting nanoparticulate mineralized collagen glycosaminoglycan (MC-GAG) material designed for advanced tissue regeneration, particularly bone repair. INNOVATION: UCLA researchers led by Professor...
Published: 9/12/2025   |   Inventor(s): Justine Lee
Keywords(s):  
Category(s): Medical Devices, Medical Devices > Surgical Tools
Gold Nanocluster-Based PROTAC Targeting pTau
​ Gold nanocluster binds both pTau and E3 ligase, initiating the ubiquitin-proteasome pathway and degrading pTau, as seen via immunostaining (Blue – Hoechst, red – TUJ1, green – pTau) Invention Summary: Hyperphosphorylated tau protein, a key clinical marker for various neurodegenerative diseases, leads to abnormal aggregation...
Published: 9/12/2025   |   Inventor(s): Sarah Nevins, Ki-Bum Lee
Keywords(s): Alzheimer’s, Drug Delivery, Inflammation, Nanoparticles
Category(s): Technology Classifications > Biomaterials, Technology Classifications > CNS Disorder, Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering
Octopus-Mimetic Adhesives for Wet Surface Attachment
THE CHALLENGE The challenge in creating effective underwater adhesion systems lies in bridging a critical gap between advanced materials science and real-world usability, especially for industries like marine robotics, offshore maintenance, and biomedical handling. Traditional solutions either bond too permanently, require ideal flat surfaces, consume...
Published: 7/3/2025   |   Inventor(s): Michael Bartlett, Chanhong Lee
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Robotics
Targeting Plasma Extracellular Vesicles as Therapy for Severe Bacterial Pneumonia (UCLA Case No. 2025-274)
UCLA researchers in the Department of Anesthesiology & Perioperative Medicine have identified a novel method of targeting plasma extracellular vesicles to help suppress inflammation and infection during severe bacterial pneumonia. BACKGROUND: Direct and indirect lung injury such as through pneumonia or following abdominal infections can lead to...
Published: 7/17/2025   |   Inventor(s): Jae Woo Lee
Keywords(s):  
Category(s): Therapeutics > Infectious Diseases, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Respiratory And Pulmonary
Use of Endogenous Plasma Extracellular Vesicles as an Adjuvant Therapeutic for Pneumonia (UCLA Case No. 2025-236)
UCLA researchers in the Department of Anesthesiology & Perioperative Medicine have developed a novel therapeutic approach using human extracellular vesicles (EVs) to block harmful effects of bacterial outer membrane vesicles (OMVs) in Pseudomonas aeruginosa pneumonia. This strategy aims to reduce inflammation, disrupt bacterial communication, and...
Published: 7/17/2025   |   Inventor(s): Jae Woo Lee
Keywords(s):  
Category(s): Therapeutics > Respiratory And Pulmonary, Therapeutics > Infectious Diseases
Smart Phone App for Mapping Two-Spotted Spider Mite (TSSM) Populations in Strawberries
Integrates a Deep Learning Model Enabling Real-Time TSSM Detection and Precise Miticide Application This smartphone app integrates a deep learning model to detect and map two-spotted spider mite (TSSM) populations in strawberries, enabling growers to precisely and accurately treat them. Every year, thousands of strawberry growers face significant yield...
Published: 6/27/2025   |   Inventor(s): Won Suk Lee, Congliang Zhou, Alireza Pourreza
Keywords(s):  
Category(s): Technology Classifications > Software > Others
Multifunctional Bioactive Dual-Layered Nanofibrous Matrix for Triple Negative Breast Cancer
​ Dual-Layered Nanofibrous Matrix designed for rapid-release and sustained-release of various therapeutics, leading to no tumor recurrence in triple negative breast cancer 4T1 tumor-resected mouse models. Invention Summary: Triple-negative breast cancer (TNBC), a particularly aggressive subtype of breast cancer which comprises 15-20% of all...
Published: 8/20/2025   |   Inventor(s): Sungyun Kim, Ki-Bum Lee, Hyun-Jong Cho
Keywords(s): Anti-cancer, Breast Cancer, Drug Delivery, Nanotechnology, Wound healing
Category(s): Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
Artificial nitrogenase enzymes for ambient-condition, decentralized ammonia production
Background Ammonia synthesis is foundational to global agriculture and chemical manufacturing, providing the primary source of fixed nitrogen for fertilizers, polymers, and pharmaceuticals. Traditional ammonia production through the Haber-Bosch process, however, operates under extreme conditions—temperatures exceeding 400°C and pressures...
Published: 7/2/2025   |   Inventor(s): Yi Lu, Hirbod Heidari, Markus Ribbe, Yilin Hu, Chi Chung Lee, Evan Mirts
Keywords(s):  
Category(s): Life sciences > Therapeutics > Synthetic biology, Life sciences > Metabolic engineering
DNA Secondary Structure (G-quadruplex) Stabilizers Improve Muscle Repair in Acute Injuries, Exercise, and Aging
Essential stem cell maintenance genes, including Pax7, a transcription factor fundamental to preserving the high regenerative capacity of muscles, is induced via targeting DNA secondary structures. Problem: Tissue restoration is essential to maintain skeletal muscles after injury. Skeletal muscle regeneration is exclusively achieved by the bona fide...
Published: 8/5/2025   |   Inventor(s): Foteini Mourkioti, Ji-Hyung Lee
Keywords(s): Aging, Drug Target, Orthopedics, Regenerative Medicine, Small Molecule
Category(s): Technology Classifications > Therapeutics
Gamified Physical Therapy Rehabilitation System
Advantages: Turns muscle movement into gameplay using wearable EMG sensors Personalizes difficulty based on each user’s strength and ability Keeps patients engaged and motivated with real-time feedback and rewards Designed for at-home or clinical use, with easy setup and data tracking Summary: Physical therapy with a licensed physical...
Published: 6/6/2025   |   Inventor(s): Antonio Gonzalez, Gabriel Mozombite Gallegos, Ashley Pham, Nathan Schilaty, John Templeton, Voon Hee Lee
Keywords(s): Devices for Disabilities / Rehabilitation, Digital Healthcare, Human Computer Interfaces, Medical Devices, Neurodegenerative Diseases, Simulation Training Aid, Wearable Electronics
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Medical Devices
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