Search Results - lee+lee

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Amine- and Ammonium-Modified Silicones for Direct Air Capture of CO2

Background The field of carbon dioxide (CO2) capture is rapidly growing due to an increasing need to effectively remove CO2 from the atmosphere. New technologies are currently being developed to target CO2 in various types of sources. One particular method of CO2 capture that has gained traction in recent years is membrane-based separation, which is...

Published: 3/6/2025 | Inventor(s): Matthew Green, Klaus Lackner, Jae Sang Lee

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Category(s): Advanced Materials/Nanotechnology, Physical Science, Environmental

A novel approach to the treatment of EGFR mutant non-small cell lung cancer (NSCLC)

Background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for ~85% of all lung cancer cases. NSCLC is slow growing and often diagnosed at later stages when it has already spread, making treatment difficult. Resistance to therapy is a major challenge in effectively treating patients with NSCLC. 10-30% of...

Published: 3/17/2025 | Inventor(s): Jack Elias, Suchitra Kamle, Chun Geun Lee, Bing Ma

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Category(s): Oncology

Alternative Translation Initiation and Termination of Immunoglobulin (Ig) Folds (AltIg) for the Synthesis of Bifunctional Polypeptides

This invention is a novel way to create Alternative Igs (AltIgs). This invention could be used to fuse two proteins together as a single polypeptide by fusing the AltIg end of one protein to the other protein. This would create a different spatial relationship between the proteins than could be achieved if the native Ig was fused in a conventional manner. Background: Fusing...

Published: 3/5/2025 | Inventor(s): Michael Kuhns, Mark Lee, Deepta Bhattacharya

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Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Healthcare Portfolios > Oncology

Intervertebral Disc Repair Using a 3D Porous Hybrid Protein Nanoscaffold

Histological analysis of rat intervertebral disc tissue prior to (left) and post injury (center) compared to 6 weeks post treatment (right). Invention Summary: Degeneration of fibrocartilaginous tissues, such as intervertebral discs (IVD), knee menisci, and other tendon-bone junctions, can lead to debilitating pain. IVD degeneration is the...

Published: 3/25/2025 | Inventor(s): Ki-Bum Lee, Letao Yang, Inbo Han

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Category(s): Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Biomaterials

Cell-Based Biosensor for Monitoring Neuronal Stem Cell Differentiation

Movement of fluorescent cargo (EGFP, green) from the cytoplasm to the nucleus (Hoechst, blue) as early as 10 minutes after stimulation with hippocalcin Invention Summary: Monitoring neuronal differentiation in stem cells is vital to advance regenerative stem cell therapies and our understanding of various neurodegenerative diseases. Traditional...

Published: 2/21/2025 | Inventor(s): Ki-Bum Lee, Youngeun Kwon, Euiyeon Lee

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Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices

Cell-Based Biosensor for Monitoring Neuronal Stem Cell Differentiation

Published: 2/21/2025 | Inventor(s): Ki-Bum Lee, Youngeun Kwon, Euiyeon Lee

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Portable ECMO with Avian Lung Structure

Current available extracorporeal membrane oxidation (ECMO) units are expensive, not portable and leave patients confined to hospitals and requiring the care of highly trained personnel. With a growing number of end stage lung disease patients and those waiting for lung transplants, there is a critical unmet need for effective, economical and convenient...

Published: 2/25/2025 | Inventor(s): Daniel Weiss, Darcy Wagner, Sean Wrenn, Franziska Uhl, Ethan Griswold, Patrick Lee, Dryver Huston

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Category(s): Technology Classifications > Biomedical

Endoglin Antibody

This technology is directed to an antibody to a mutated endoglin protein. Specifically, this antibody provides methods and compositions for detecting splice variants of the endoglin protein, enabling the accurate diagnosis of cancer. This invention further includes the use of endoglin-specific antibodies to enhance the detection process, offering a...

Published: 1/29/2025 | Inventor(s): Nam Lee

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Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Antibodies

Modular and Scalable Solar Microinverter

Executive Summary Induction motors are used in a myriad of applications. Often, however, they are oversized and draw high starting currents which typically incurs additional electricity charges. For pumping applications, this can also lead to excess wear of the pump and piping system. While a variable speed drive (VSD) may alleviate this problem, VSD’s...

Published: 1/6/2025 | Inventor(s): Woongkul Lee, Younsuk Dong, Musab Guven

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Category(s): Mobility, Electrical, Energy

System for Closed-Loop Deep Brain Stimulation Using Neural and Behavioral Biomarkers of Specific Motor Features

System for Closed-Loop Deep Brain Stimulation Using Neural and Behavioral Biomarkers of Specific Motor Features Overview Parkinson’s Disease (PD) is characterized by distinct motor phenomena that are expressed asynchronously. Understanding the neurophysiological correlates of these different motor states could enable optimal closed-loop neuromodulation....

Published: 3/5/2025 | Inventor(s): Wael Asaad, Shane Lee, Umer Akbar, Peter Lauro

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Category(s): Central Nervous System(CNS), Biomarker, Neurodegenerative Disease

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