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Search Results - jae+woo+lee
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Targeting Plasma Extracellular Vesicles as Therapy for Severe Bacterial Pneumonia (UCLA Case No. 2025-274)
UCLA researchers in the Department of Anesthesiology & Perioperative Medicine have identified a novel method of targeting plasma extracellular vesicles to help suppress inflammation and infection during severe bacterial pneumonia. BACKGROUND: Direct and indirect lung injury such as through pneumonia or following abdominal infections can lead to...
Published: 7/20/2026
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Updated: 6/27/2025
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Inventor(s):
Jae Woo Lee
Keywords(s):
Category(s):
Therapeutics > Infectious Diseases
,
Therapeutics > Inflammation And Inflammatory Diseases
,
Therapeutics > Respiratory And Pulmonary
Use of Endogenous Plasma Extracellular Vesicles as an Adjuvant Therapeutic for Pneumonia (UCLA Case No. 2025-236)
UCLA researchers in the Department of Anesthesiology & Perioperative Medicine have developed a novel therapeutic approach using human extracellular vesicles (EVs) to block harmful effects of bacterial outer membrane vesicles (OMVs) in Pseudomonas aeruginosa pneumonia. This strategy aims to reduce inflammation, disrupt bacterial communication, and...
Published: 7/20/2026
|
Updated: 6/27/2025
|
Inventor(s):
Jae Woo Lee
Keywords(s):
Category(s):
Therapeutics > Respiratory And Pulmonary
,
Therapeutics > Infectious Diseases
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit Endospores
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit EndosporesResearchers at Augusta University have invented skin-friendly compositions and methods for killing, inactivating, or otherwise reducing the bacterial endospores by using an effective amount of the green tea EGCG or its derivatives. EGCG research shows clear application for a hand sanitizer...
Published: 4/21/2023
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Updated: 1/15/2021
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Inventor(s):
Stephen Hsu
,
Lee Lee
,
Tin-Chun Chu
Keywords(s):
Category(s):
Therapeutics
Microfluidic 3D Osteocyte Network Reconstructured With Microbeads As Scaffold
Background: Mature osteocytes embedded in the three-dimensional lacuna-canalicular network (3D-LCN) structure are known to sense local compressive strain and initiate strain-dependent new bone formation by osteoblasts, utilizing cytokines such as sclerostin and Dkk1 expressed by the osteocytes as major signaling molecules. Studying these osteocytes...
Published: 7/24/2026
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Updated: 5/19/2015
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Inventor(s):
Woo Lee
,
Yexin Gu
,
Wenting Zhang
,
Qiaoling Sun
,
Jenny Zilberberg
Keywords(s):
Category(s):
Bio Technology (Rx, dev's, sys)
An Ex Vivo Human Multiple Myeloma Cancer Niche and Its Use As a Model for Personalized Treatment of Multiple Myeloma
Background:Primary patient-derived multiple myeloma cells (MMC) are difficult to preserve . Long-term survival of osteoblasts, OSB, is the most critical factor in maintaining the ex vivo viability and proliferative capacity of MMC. The adhesion and retention of MMC to the tissue scaffold was meditated by osteoblastic N-cadherin, as one of potential...
Published: 7/24/2026
|
Updated: 5/19/2015
|
Inventor(s):
Woo Lee
,
Wenting Zhang
,
Peter Tolias
,
Hongjun Wang
,
Jenny Zilberberg
,
David Siegel
Keywords(s):
Category(s):
Bio Technology (Rx, dev's, sys)