Search Results - hypertension

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2022-088 Neural Networks for Adipose Tissue Segmentation on Magnetic Resonance Images
Summary: UCLA researchers in the Department of Radiological Sciences have developed a novel neural network that can segment and quantify visceral and subcutaneous adipose tissues on magnetic resonance images automatically, accurately, and rapidly, to enhance clinical methods for characterizing and monitoring risk for cardiometabolic diseases in patients...
Published: 9/25/2024   |   Inventor(s): Holden Wu, Sevgi Gokce Kafali-Tekat
Keywords(s): Advanced Computing / AI, Artificial Neural Network, Artificial Neural Network Artificial Neuron, cardiometabolic disease, Hypertension, Imaging, Machine Learning, Magnetic Resonance Imaging, Magnetic Resonance Imaging Pathology, Medical Imaging, MRI, multi-contrast imaging, obesity, Tissue (Biology), tissue annotation, tissue detection, tissue ribbons alignment, tissue segmentation
Category(s): Medical Devices > Medical Imaging, Platforms > Diagnostic Platform Technologies, Medical Devices > Medical Imaging > MRI, Therapeutics > Metabolism And Endocrinology
2020-859-1 Novel Approach to Modulate Renal Neurotransmission via Percutaneous
SUMMARY: UCLA researchers in the Department of Medicine-Cardiology have developed a method that applies renal denervation to specific renal arteries to treat resistant hypertension. BACKGROUND: Sympathetic nervous system activation occurs when chemicals, such as adrenaline, bind to multiple receptors that are responsible for vital functions such...
Published: 8/2/2023   |   Inventor(s): Olujimi Ajijola
Keywords(s): Artery, Blood Pressure, Hypertension, Hypertension Urine, Kidney, Medical Device, Renal, Surgery
Category(s): Life Science Research Tools, Diagnostic Markers, Medical Devices
Treatment for Hypertension
Technology Description This technology opportunity provides antisense oligomer compounds and methods for the treatment of hypertension that overcome the various limitations and drawbacks associated with the use of substrate inhibitors. The compounds accumulate in the kidney, which allows for efficient dosing, and can be developed for transdermal, subcutaneous,...
Published: 1/16/2023   |   Inventor(s): Patrick Iversen, Andrew Annalora
Keywords(s): Hypertension, pharmaceuticals, Transplantation
Category(s): Therapeutics
AAV Gene Therapy for Complications with Diabetes and Vascular Diseases
AAV Vectors Rely on Tissue-Specific Promoters to Target Vascular Endothelial Cells This AAV gene therapy transduces vascular endothelial cells and targets complications associated with diabetes and other vascular diseases. Available gene therapy vectors do not efficiently or selectively transduce vascular endothelial cells, which are associated with...
Published: 6/27/2021   |   Inventor(s): William Hauswirth, Sanford Boye, Michael Boulton, Shannon Boye, Daniel Lipinski
Keywords(s): AAV, Diabetes, Gene Therapy, hypercholesterolemia, Hypertension, retinal disease, vascular endothelial junctions, Vascular Repair
Category(s): Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Human Health Care > Therapeutics
Humanized Endothelial Specific TRPC3 Transgenic Mouse
Project: D2012-18 Strains: EST3Tg/C57BL6 and EST3Tg/Apoe-/- Type: Humanized transgenic mouse Background: In the U.S., atherosclerosis, hypertension and stroke are the major causes of death due to cardiovascular disease and remain most frequent vascular complications of metabolic diseases such as diabetes, obesity and metabolic syndrome. A common...
Published: 5/9/2024   |   Inventor(s): Guillermo Vazquez
Keywords(s): Atherosclerosis, Cardiovascular, Endothelial Dysfunction, Hypertension, Mouse, TRPC3, Vascular Permeability
Category(s): Tools