Search Results - trpc3

2 Results Sort By:
TRPC Knockout (KO) Mice and Mice with a Floxed Allele of TRPC Ion Channel Genes
TRPCs (Canonical Transient Receptor Potential Channels) are a group of non-selective cation channels that allow sodium and calcium into cells. There are seven different genes in mice that code TRPCs. The in vivo roles played by TRPCs as a whole are poorly understood and very little is known about the in vivo roles played by individual TRPCs nor the...
Published: 10/28/2024   |   Inventor(s): Joel Abramowitz, Lutz Birnbaumer
Keywords(s): ALLELE, CHANNEL, Floxed, Gene, ION, Knockout, Listed LPM Tong as of 4/15/2015, Mice, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, TRPC3, TRPC5, TRPC7, WBXXXX, WIXXXX, WJXXXX, WKXXXX, XEXXXX, YAXXXX
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Application > Research Materials, Application > Diagnostics
Humanized Endothelial Specific TRPC3 Transgenic Mouse
Project: D2012-18 Strains: EST3Tg/C57BL6 and EST3Tg/Apoe-/- Type: Humanized transgenic mouse Background: In the U.S., atherosclerosis, hypertension and stroke are the major causes of death due to cardiovascular disease and remain most frequent vascular complications of metabolic diseases such as diabetes, obesity and metabolic syndrome. A common...
Published: 5/9/2024   |   Inventor(s): Guillermo Vazquez
Keywords(s): Atherosclerosis, Cardiovascular, Endothelial Dysfunction, Hypertension, Mouse, TRPC3, Vascular Permeability
Category(s): Tools