Search Results - xudong+wang

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Telodendrimer Nanoparticles for Protein Delivery
A nanoparticle-based method for enhanced delivery of protein/peptide therapeutics. Background: Biologics, for example protein and peptide-based therapeutics, have poor in vitro shelf stability and in vivo enzymatic stability, which lead to short blood circulating time and contribute to immunogenicity. In addition, biologics are impermeable to biological...
Published: 5/13/2025   |   Inventor(s): Juntao Luo, Xu Wang, Changying Shi, Alexa Bodman, Walter Hall
Keywords(s): cancer therapy, lipidoids, nanoparticles, protein delivery, telodendrimers
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
A High-Throughput NMR Method for In-Membrane Ligand-Screening
Advantages: Maintains the original structural and functional properties of receptor proteins Enables high-throughput screening through automated NMR workflows with minimal sample quantities Enhanced Signal-to-Noise Ratio improves detection of ligand-receptor interactions (e.g. binding orientations, kinetics, and dynamics) Applicable to any membrane...
Published: 4/30/2025   |   Inventor(s): Libin Ye, Xudong Wang
Keywords(s): Drug Delivery and Nanomedicine, Drug Discovery
Category(s): Technology Classifications, Technology Classifications > Chemistry, Technology Classifications > Medical > Biotechnology
Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration
Abstract: Retinal degeneration is a deteriorative condition of the human retina caused by the progressive and eventual death of photoreceptor cells. To date, no effective treatment for genetically inherited or age-associated retinal degeneration, which includes a large patient population worldwide, is available. Researchers at the National Eye Institute...
Published: 5/15/2025   |   Inventor(s): Wai Wong, Lian Zhao, Xu Wang, Wenxin Ma
Keywords(s): Age-Related Degeneration, AMD, Estrogen-receptor, Microglial Inhibition, National Eye Institute, NEI, Photoreceptor, Retinal degeneration, Retinitis Pigmentosa, RP
Category(s): Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology
Treating Malaria Using Novel Clinical Drug Candidates that Exhibit Oral Efficacy with Once Daily Dosing
Treating Malaria Using Novel Clinical Drug Candidates that Exhibit Oral Efficacy with Once Daily Dosinghttps://sites.google.com/slu.edu/intellectualproperty/2017/17-036
Published: 1/24/2022   |   Inventor(s): Marvin Meyers, Cynthia Dowd, Xu Wang, Robert Brothers, Audrey John, Rachel Edwards
Keywords(s):  
Category(s): Therapeutics
3D-Soft Electrode for Li-Chalcogen Batteries
3D-Soft Electrode for Li-Metal Batteries Background Due to their high theoretical current density, Li-Air, Li-sulfur, and Li-selenium batteries have attracted a great deal of attention. Their high energy density, which can be two orders of magnitude greater that current lithium ion batteries, makes them ideal for applications ranging from automotive...
Published: 2/13/2025   |   Inventor(s): Hanqing Jiang, Xu Wang, Wei Zeng
Keywords(s): Agriculture and Animal Science, Fuel Cells, Energy, Materials and Electronics
Category(s): Physical Science, Applied Technologies, Energy & Power
Novel Efficiency Boost Technology for Smart SR Drivers in LLC based DC-DC Converters
Today’s PC and Server power supplies employ 400VDC à 12VDC LLC power converters which typically have 91-92% efficiencies when using standard schottky diodes for rectification. Using MOSFETs as synchronous rectifiers increases efficiency to 94-95% due mainly to their very low ON resistance. Researchers in the Department of Electrical Engineering...
Published: 6/22/2022   |   Inventor(s): Yan-Fei Liu, Dong Wang
Keywords(s):  
Category(s): Electronics, Power Electronics