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Self-Replicating Cell-Selective Therapy for Atherosclerotic Cardiovascular Disease
­Advantages: It utilizes a targeted approach by selectively expressing the therapeutic agent in vascular smooth muscle cells and infiltrating immune cells, it minimizes potential off-target effects and preserves the function of the endothelial cells. By combining two complementary mechanisms, the miRNA switch and siRNA technology, this research...
Published: 6/11/2024   |   Inventor(s): Isabella Hetherington
Keywords(s): Cardiovascular Diseases, Drug Delivery and Nanomedicine
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals