Search Results - diagnostic+assays%2fdevices

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Reagent Molding Process for Point of Care Microfluidic Applications
Invention Description Lyophilization is a critical process for stabilizing reagents in point-of-care (POC) diagnostics, effectively eliminating the need for cold chain storage and preventing liquid evaporation. While this technology is essential for developing robust field-deployable devices, current industry standards are limited to producing reagents...
Published: 1/26/2026   |   Inventor(s): Jennifer Blain Christen, Vi Nguyen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care
User-Actuated Valve Actuator for Microfluidic Devices
Invention Description Lab-on-a-chip technology and microfluidic diagnostic devices often rely on complex mechanical or electrical systems to manipulate fluid, making them costly and bulky. These components may limit portability, decrease operational lifetime, and prevent widespread use by untrained personnel or patients at the point of care or at home....
Published: 1/12/2026   |   Inventor(s): Clifford Anderson, Vi Nguyen, Jennifer Blain Christen
Keywords(s): Analytical Devices, Bioassay, Biosensor, Fluid, Micro-Fluidics
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Point of Care
Integrated Microfluid Cartridge for POC Biofluid Diagnostics
Invention Description Rapid and reliable nucleic acid assays are critical for diagnosing infectious diseases at the point of need, yet most systems rely on complex, expensive instrumentation and trained personnel. These requirements limit access to timely diagnostics in low-resource, remote, or decentralized settings. Many platforms typically require...
Published: 1/6/2026   |   Inventor(s): Vi Nguyen, Clifford Anderson, Jennifer Blain Christen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Coronavirus, COVID-19, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care, SARS-CoV-2
Fluorescently Labeled INtracellular Genomics (FLING) and Fluorescent In Situ Amplified (FISA)
Invention Description Accurately identifying and sequencing rare genotypes within complex cell populations remains a major challenge across biological research. Conventional sequencing approaches often require large amounts of high-quality DNA, struggle with heterogeneous or degraded samples, and fail to retain the spatial or cellular context necessary...
Published: 12/11/2025   |   Inventor(s): Kerry Geiler-Samerotte, Leandra Brettner, Parker Crossland, Kara Schmidlin
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Imaging
Multiomic Approaches to Pediatric Inflammatory Bowel Disease
Invention Description Pediatric Inflammatory Bowel Disease (IBD), encompassing Crohn’s Disease and Ulcerative Colitis, presents significant clinical challenges due to its complex and heterogeneous nature, often leading to lifelong health complications. Current diagnostic and therapeutic strategies are limited by an incomplete understanding of...
Published: 1/17/2026   |   Inventor(s): Todd Sandrin, Peter Jurutka, Haiwei Gu, Brad Pasternak
Keywords(s):  
Category(s): Applied Technologies, Diagnostic Assays/Devices, Life Science (All LS Techs), Pharmaceuticals, Proteomic Assays/Reagents/Tools, Artificial Intelligence/Machine Learning
Unified Model of Alzheimer’s Disease Pathobiology
Invention Description Understanding of the pathobiology of Alzheimer’s disease (AD) has long been fragmented, with much research centered around biological mechanisms including amyloid β or tau proteins, inflammation, cell death pathways, glia, mitochondria and more. While these all deal with real facets in the biology of AD, they are limited...
Published: 1/6/2026   |   Inventor(s): Carol Huseby, Elaine Delvaux, Paul Coleman
Keywords(s):  
Category(s): Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Neurodegenerative Disease Technologies, Pharmaceuticals
Microfluidic Device Design for Point-of-Care Devices
Implementing liquid-based assays, such as PCR and LAMP, is difficult in POC microfluidic devices, due to bubble formation. To mitigate this, auxiliary metering systems or actuators are required to regulate consistent flow rates. This can make the microfluidic device more complicated to operate, increases cost, and limits rapid prototyping, ultimately...
Published: 9/29/2025   |   Inventor(s): Vi Nguyen, Jennifer Blain Christen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Diagnostics/Sensors, Genomic Assays/Reagents/Tools
POC-Pure: Rapid, Cost-Effective Nucleic Acid Extraction for Point-of-Care Salivary Diagnostics on a Microfluidic Chip
Point-of-care (POC) testing techniques are essential in molecular diagnostics, particularly in resource-limited settings. The first step in molecular diagnostics is sample preparation which may include extraction of nucleic acids (NAs). Simple and efficient NA extraction is crucial for downstream applications such as pathogen detection, genetic analysis,...
Published: 9/18/2025   |   Inventor(s): Siril Arockiam, Karen Anderson
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Medical Diagnostics/Sensors
Brain-Targeted Nanoparticles for Delivering Agents to the Brain
The blood brain barrier (BBB) is a highly selective semipermeable complex, and only about 2% of small molecules in the blood can penetrate it. Because of this, drug delivery to the brain is fairly ineffective. Research into receptors expressed on the BBB is promising, however, many receptors (glucose transporter 1, transferrin receptor, LDL-receptor...
Published: 8/27/2025   |   Inventor(s): Shu Wang, Zhaoyang Fan
Keywords(s):  
Category(s): Biological Nanotechnology, Diagnostic Assays/Devices, Imaging, Life Science (All LS Techs), Pharmaceuticals, Medical Imaging, Non-Cancer Therapeutics
Antimicrobial Antibody Signatures of IBD
The incidence of inflammatory bowel disease (IBD), which includes Chron’s disease (CD) and ulcerative colitis (UC), is increasing globally, as is the healthcare burden, with studies showing it as one of the top 5 most expensive GI conditions. Early and accurate diagnosis is strongly associated with better patient outcomes. However, the common...
Published: 8/27/2025   |   Inventor(s): Mahasish Shome, Lusheng Song, Yunro Chung, Jonathan Leighton, Joshua LaBaer, Ji Qiu
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
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