Search Results - diagnostic+assays%2fdevices

108 Results Sort By:
Rapid Tuberculosis and Mycobacteria Phenotypic Drug Susceptibility Testing
Mycobacterium tuberculosis (TB) remains a major global health threat, causing nearly 1.5 million deaths annually, making it the 13th leading cause of death. While TB is preventable and treatable, multidrug-resistant TB worsens the global health crisis, making diagnosis and treatment more complex. An even greater challenge is heteroresistance, where...
Published: 4/8/2025   |   Inventor(s): Shelley Haydel, Shaopeng Wang, Jiapei Jiang, Yannik Haller
Keywords(s):  
Category(s): Artificial Intelligence/Machine Learning, Vaccines/Antimicrobials, Life Science (All LS Techs), Imaging, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices
High-Throughput DNA Origami Nanoarrays
Traditional bulk diagnostic assays suffer from signal dilution and averaging, making it difficult to detect rare biomarkers and subtle molecular variations critical for early disease diagnosis. Microarrays address this limitation by enabling high-throughput, multiplexed analysis with improved specificity and sensitivity. Their structured array format...
Published: 3/27/2025   |   Inventor(s): Prathamesh Chopade, Rizal Hariadi
Keywords(s): DNA nanotechnology, Lithography, MicroArray, Nanofabrication, Nucleic Acid, Single Molecule
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Biological Nanotechnology, Diagnostic Assays/Devices, Life Science (All LS Techs)
Microfluidic Digital Nanobiosensor for Point-of-Care Detection of NT-proBNP
Heart failure is a serious global burden affecting more than 64 million people worldwide. It has high morbidity and mortality and poor quality of life, making it a major public health priority. N-terminal proBNP (NT-pro-BNP) is a well-established clinical biomarker for monitoring and managing heart failure. Regular and frequent monitoring of patients...
Published: 2/13/2025   |   Inventor(s): Shaopeng Wang, Chao Chen
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Medical Devices
Breath-Based Diagnostics for Lower Respiratory Infections
Acute pulmonary infections, or pneumonia, are a leading cause of infectious death worldwide with more than 2.3 million deaths each year. Existing strategies for diagnosing pneumonia are based on clinical, radiological and microbial criteria, which is time-consuming, low accuracy, and subject to interobserver variability. Furthermore, obtaining a lower...
Published: 2/13/2025   |   Inventor(s): Heather Bean, Emily Higgins Keppler
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Diagnostic Assays/Devices
Anti-Galectin-1 Monoclonal Antibody
Galectin-1 (Gal-1) is a ubiquitously expressed galactoside-binding 14-kDa lectin that is differentially expressed by a variety of pathological as well as normal cell types. Extracellular Gal-1 has been shown to exert strong Immunomodulatory activity and has been implicated in numerous cancer and autoimmune diseases. Further, recent research has shown...
Published: 2/13/2025   |   Inventor(s): Douglas Lake, Kirsten Pfeffer, Thai Ho
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Cancer, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
Tandem Antigen Capture ELISAs for Measuring Short and Long Isoforms of QSOX1
Quiescin sulfhydryl oxidase1 (QSOX1) is a sulfhydryl oxidase that is overexpressed in several malignancies and as such is a potential biomarker for multiple cancer types as well as acute decompensated heart failure (ADHF). Since its discovery, QSOX1 has been identified as a key player in the facilitation of tumor cell migration, creating a significant...
Published: 2/13/2025   |   Inventor(s): Douglas Lake, Thai Ho, Calvin Koelbel
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Cancer, Diagnostic Assays/Devices, Medical Diagnostics/Sensors, Life Science (All LS Techs)
DNA Sequencing and Mutation Rate Estimation
DNA mutations are the basis of all heritable biological variation. Some variation gives rise to beneficial traits, many are neutral or nearly neutral, and some result in deleterious phenotypes. While it is commonly believed that DNA mutations affect evolutionary phenotypic trajectories over millions of years, scientific advances have shown that this...
Published: 2/13/2025   |   Inventor(s): Stephan Baehr, Jean-Francoi Gout, Michael Lynch
Keywords(s):  
Category(s): Applied Technologies, Computing & Information Technology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs)
Diagnostic and Prognostic Biomarkers for ALS
Amyotrophic Lateral Sclerosis (ALS) is a terminal neurodegenerative disease defined by the progressive loss of motor neuron function. Despite intense research efforts, clinical outcomes in ALS patients have remained limited. Because there are no diagnostic or prognostic biomarkers for ALS, patients are classified based on the site of symptom onset,...
Published: 2/13/2025   |   Inventor(s): Jarrett Eshima, Barbara Smith, Chris Plaisier
Keywords(s):  
Category(s): Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Neurodegenerative Disease Technologies
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 2/13/2025   |   Inventor(s): Li Liu, Jingmin Shu
Keywords(s):  
Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices
System to Rapidly Screen and Detect Small Molecules
The analysis of small-molecule metabolites and drugs in body fluids and tissue extracts plays a vital role in human health, food safety and environmental monitoring. The current gold standard for small molecule detection is mass spectrometry, which is expensive, time consuming, and requires trained personnel. Universal point-of-care (POC) testing would...
Published: 3/20/2025   |   Inventor(s): Chao Wang, MD Ashif Ikbal
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Life Science (All LS Techs), Diagnostic Assays/Devices
1 2 3 4 5 6 7 8 9 10 ...