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Search Results - dermatology
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Indolium 1 for Advanced Melanoma Treatment
Application A small molecule compound for the treatment of melanoma. Key Benefits Novel small molecule compound for the treatment of resistant melanoma. Well tolerated in vivo. Market Summary Malignant melanoma is a type of skin cancer that begins in melanocyte cells. Melanoma is the 19th most commonly occurring cancer. Exposure to UV radiation...
Published: 7/30/2024
|
Inventor(s):
Jack Arbiser
Keywords(s):
Dermatology
,
Oncology
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
Topical LSD1 Inhibition for Treating Skin Diseases
Topical LSD1 inhibition can treat skin diseases that include cutaneous squamous cell carcinoma (cSCC), actinic keratoses, and viral warts. Problem: Current treatment options (i.e. cryotherapy, laser therapy, surgery, chemotherapy) for skin diseases such as cSCC, actinic keratoses, and viral warts are often non-targeted and destructive, and can cause...
Published: 2/12/2024
|
Inventor(s):
Brian Capell
,
Napasorn (Nina) Kuprasertkul
Keywords(s):
Dermatology
,
Drug Delivery
,
Drug Target
,
Immunoncology
,
Oncology
Category(s):
Technology Classifications > Therapeutics
Targeted light-based therapy for acne
Summary Acne is the most common skin condition, with direct treatment costs totaling over $3 billion each year. Vanderbilt researchers have developed a photodynamic therapy (PDT) for effectively and specifically treating Propionibacterium acnes infections, enabling improved clinical support for patients. Addressed Need More than 90% of the global...
Published: 9/4/2024
|
Inventor(s):
Keywords(s):
Dermatology
,
Infectious Disease
Category(s):
Therapeutics
Stretchable, Adhesive, and Self-Healing Hydrogels for Next-Generation Medical Adhesives
A hydrogel that can naturally stretch and self-heal while adhering to the body, enabling new designs for medical adhesives. Problem: Hydrogels are naturally biocompatible materials which could revolutionize diverse medical technologies ranging from artificial muscles to wearable electronics. Their simple non-toxic composition along with their non-rigid...
Published: 10/16/2023
|
Inventor(s):
Shu Yang
,
Mingtao Chen
,
Baohong Chen
Keywords(s):
Bioengineering
,
Dermatology
,
Hydrogels
,
Soft Materials
Category(s):
Technology Classifications > Medical Devices
,
Technology Classifications > Chemical Processes and Synthesis
,
Technology Classifications > Materials
Targeted photodynamic therapy for S. aureus infections
Summary Staphylococcus aureus is among the most prevalent pathogens in skin and soft tissue infections, with treatments becoming increasingly compromised by the emergence of methicillin-resistant S. aureus (MRSA). Vanderbilt researchers have developed a combination photodynamic therapy (PDT) for targeting MRSA infections in skin that is not only effective...
Published: 8/9/2023
|
Inventor(s):
Keywords(s):
Dermatology
,
Infectious Disease
Category(s):
Therapeutics
PKC412 restores functionality of the keratin cytoskeleton in the skin disorder epidermolysis bullosa simplex
Invention Summary: Epidermolysis bullosa simplex (EBS) is a highly penetrant genetic condition that causes fragility of skin keratinocytes resulting in fluid-filled skin blisters that erode upon scratching or minor pressure on the skin. There is no good cure for EBS, and treatment typically involves preventive and/or supportive care...
Published: 5/2/2024
|
Inventor(s):
Bishr Omary
,
Thomas Magin
,
Jacques Roberge
,
Katrin Rietscher
,
Pei Li
Keywords(s):
Dermatology
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Rare Disease
2012-340 A Novel Basic Fibroblast Growth Factor Conjugate for Broad Therapeutic Application
A Novel Basic Fibroblast Growth Factor Conjugate for Broad Therapeutic ApplicationSUMMARYUCLA scientists have developed a novel polymer conjugate of basic fibroblast growth factor (bFGF) for use in commercial and possibly clinical applications. This is the first bFGF conjugate to enhance bioactivity and stability under environmental stressors. BACKGROUNDBasic...
Published: 7/19/2023
|
Inventor(s):
Heather Maynard
,
Thi Nguyen
Keywords(s):
Catalysts
,
Dermatology
,
Other Polymers
,
Therapeutics & Vaccines
Category(s):
Chemical > Synthesis
,
Therapeutics
,
Therapeutics >
Dermatology
,
Platforms > Drug Delivery > Other Polymers
2004-087 Antimicrobial Peptide for the Treatment of Skin Diseases
Antimicrobial Peptide for the Treatment of Skin DiseasesSUMMARYGranulysin peptides are small antimicrobial agents with potent activity against bacteria and inflammation. A pharmaceutical composition comprising granulysin peptides as an active agent is administered therapeutically to a patient suffering from a microbial infection.
Published: 7/19/2023
|
Inventor(s):
David Eisenberg
,
Robert Modlin
,
Jenny Kim
,
Daniel Anderson
,
Richard Gallo
Keywords(s):
Dermatology
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics >
Dermatology
2010-243 Application of Topical Resveratrol in the Treatment of Acne
Application of Topical Resveratrol in the Treatment of AcneSUMMARYResearchers in UCLA Department of
Dermatology
have demonstrated through in vitro experiments that resveratrol, an ingredient in antioxidants and anti-aging products, generates sustained bactericidal and anti-inflammatory effects against P. acnes, the bacteria involved in the pathogenesis...
Published: 7/19/2023
|
Inventor(s):
Emma Taylor
,
Jenny Kim
,
Jackson Champer
Keywords(s):
Agbio
,
Dermatology
,
Nutraceuticals / Probiotics
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics >
Dermatology
,
Therapeutics > Agtech And Animal Health
,
Therapeutics > Nutraceuticals And Probiotics
Beta Blocker Isomers as Angiogenesis Inhibitors
Application β-blocker inactive form of propranolol for treatment of angiogenic disease. Key Benefits Reduced side-effects, such as low blood pressure and low blood sugar. Increased anti-angiogenic activity compared to the active isoform. Market Summary Angiogenesis is the growth of blood vessels from the existing vasculature. While it...
Published: 8/22/2024
|
Inventor(s):
Jack Arbiser
Keywords(s):
Cardiovascular
,
Dermatology
,
Oncology
,
Pediatrics
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
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