Search Results - john+lee

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Targeting Prostate Cancer with a Novel T-Cell Receptor and Tissue-Specific Cancer Antigens for Improved Immune Response (UCLA Case No. 2022-070)
Researchers from UCLA’s Department of Microbiology, Immunology, & Molecular Genetics (MIMG), and the department of Molecular and Medical Pharmacology have identified a set of tissue-specific antigens which have been used to isolate and characterize a group of novel T-cell receptors (TCRs) which target prostate cancer specifically. Furthermore,...
Published: 2/26/2024   |   Inventor(s): Owen Witte, Zhiyuan Mao, Jami Witte, Pavlo Nesterenko, John Lee
Keywords(s): Cancer, cancer antigen, Peptide, peptides, prostate cancer, protein, t-cells
Category(s): Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit Endospores
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit EndosporesResearchers at Augusta University have invented skin-friendly compositions and methods for killing, inactivating, or otherwise reducing the bacterial endospores by using an effective amount of the green tea EGCG or its derivatives. EGCG research shows clear application for a hand sanitizer...
Published: 4/21/2023   |   Inventor(s): Stephen Hsu, Lee Lee, Tin-Chun Chu
Keywords(s):  
Category(s): Therapeutics
2015-288 TRP: Derivation of a Human Neuroendocrine Prostate Cancer Cell Line with Defined Oncogenic Drivers
Derivation Of A Human Neuroendocrine Prostate Cancer Cell Line With Defined Oncogenic DriversSUMMARYResearchers at UCLA have developed a malignant neuroendocrine prostate cancer cell line that was derived from benign human prostate tissue and transformed with the oncogenes MYCN and myristoylated AKT1.BACKGROUNDHuman cell lines are an important component...
Published: 7/19/2023   |   Inventor(s): Owen Witte, John Lee
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Lines
Surfaceome Profiling of Advanced Prostate Cancer to Identify Target Antigens for Immune-Based Therapy (UCLA Case. No. 2018-571)
Surfaceome Profiling Of Advanced Prostate Cancer To Identify Target Antigens For Immune-Based TherapySUMMARYDr. Witte and colleagues at UCLA have developed a novel approach to identify surface biomarkers and targetable antigens in prostate cancer by combining multiple omics analyses across different cell lines.BACKGROUNDProstate cancer is the most common...
Published: 9/19/2024   |   Inventor(s): Owen Witte, John Lee, Nathanael Bangayan
Keywords(s): Life Science Research Tools, Research Methods
Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods