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Biocompatible photoenzymatic system for selective C–H fluorination
Background C–H fluorination plays a central role in pharmaceutical and agrochemical synthesis, as the introduction of fluorine often enhances a molecule's metabolic stability, potency, and bioavailability. Over 20% of approved drugs contain fluorinated functional groups, underscoring the demand for efficient and selective fluorination methods....
Published: 7/31/2025   |   Inventor(s): Yi Lu, Yu Zhou
Keywords(s):  
Category(s): Life sciences > Metabolic engineering
A General Cation-Exchange Approach to Magnetic Intercalation Superlattices (Case No. 2025-9A1)
Summary: UCLA researchers in the Department of Chemistry have developed a general cation-exchange approach for tunable magnetic intercalation superlattices. Background: Layered materials are crucial for engineering quantum and magnetic phenomena at the atomic scale. Magnetic intercalation superlattices, a type of layered materials, enable tunable...
Published: 7/24/2025   |   Inventor(s): Xiangfeng Duan, Yu Huang, Jingxuan Zhou
Keywords(s): Advanced Computing / AI, advanced packaging, Cation exchange, doping control, Fabrication Technologies, ferromagnetic semiconductor, layered materials, magnetic coupling, magnetic intercalation superlattices, quantum communication, Quantum Computer, quantum computing materials, Quantum Dot, quantum error correction (QEC), quantum incompressible fluid, quantum key, quantum network, quantum processing, quantum processor, room-temperature superconductivity, spin textures, spintronics, trapped ion quantum processor, tunable ferromagnetism, Van der Waals, Van Der Waals Force, VIN group metals
Category(s): Materials, Materials > Nanotechnology, Materials > Functional Materials, Materials > Semiconducting Materials, Materials > Fabrication Technologies, Materials > Metals, Optics & Photonics
Exceptional Point Optomechanical Infrared Thermal Imaging Detector (EPOPTIM)
Background Mid to long-wave infrared detectors capture and interpret infrared radiation emitted by objects, and convert it into additional data. These detectors have wide ranging applications including gas sensing, thermal imaging, environmental monitoring, and defense applications. Typically, these detectors use micro- or nano-scale microwave-frequency...
Published: 7/24/2025   |   Inventor(s): Yu Yao, Linbo Shao, Yizheng Zhu
Keywords(s):  
Category(s): Physical Science, Imaging, Environmental, Applied Technologies
Surface Oxophilic Single Atom Decoration of PT Catalyst for Anion Exchange Membrane Fuel Cells (Case No. 2025-263)
Summary: Researchers at UCLA's Department of Chemistry and Biochemistry have developed a novel catalyst design using oxophilic single-atom decorations that enhances the performance and durability of platinum (Pt) catalysts in alkaline exchange membrane fuel cells. Background: Hydrogen fuel cells are a promising alternative to internal combustion...
Published: 6/24/2025   |   Inventor(s): Xiangfeng Duan, Yu Huang, Chengzhang Wan
Keywords(s): anion exchange membrane fuel cells (AEMFCs), Catalysts, catalytic hydrogenation, clean energy, clean energy consumption, clean material production, Composite Material, Composite Materials, Construction Materials, Electrocatalyst, electrochemically active surface area, high-durability catalysts, Hydrogen, Hydrogen oxidation reaction, hydrogen oxidation reaction (HOR), hydrogen production, low overpotential catalysis, mass activity, material science, Materials, meta materials, Methane Reformer Hydrogen Production, microarchitectured materials, Nanomaterials, nanostructured materials, Nanotechnology, oxygen oxidation reaction, oxygen reduction reaction (ORR), Platinum group metal catalysts, proton exchange membrane fuel cells (PEMFCs), proton exchange water membrane electrolyzer (PEMWE), Rhodium-decorated Platinum nanowires (SARh-PtNW), specific activity, transition metal catalysts
Category(s): Materials, Materials > Nanotechnology, Materials > Functional Materials, Energy & Environment, Energy & Environment > Energy Generation, Energy & Environment > Energy Efficiency, Energy & Environment > Energy Transmission, Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Synthesis, Chemical > Catalysts
Multi-Object Grasping -- Grasping from Surface of Pile
Advantages: High Efficiency in Cluttered Environments Vision-Guided Dexterity with 6D Pose Estimation Confidence-Driven Grasp Optimization Adaptive to Real-World Variability Scalable for Industrial Automation Summary: Robotic grasping in industries like manufacturing, warehousing, and logistics is still a bottleneck when dealing with dense...
Published: 5/28/2025   |   Inventor(s): Tianze Chen, Yu Sun
Keywords(s): Robotics
Category(s): Technology Classifications > Engineering > Chemical Engineering, Technology Classifications > Engineering > Mechanical Engineering, Technology Classifications > Engineering > Industrial Engineering
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025   |   Inventor(s): Stephen Liggett, Donghwa Kim, Yu Chen, Jesper Madsen, Steven An
Keywords(s): Pharmaceuticals, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals
Multi-material electrospinning system for 3D-printed fiber architectures
Background Electrospinning and additive manufacturing have become increasingly important in fields such as biotechnology, pharmaceuticals, and tissue engineering, where there is growing demand for complex fiber architectures and multifunctional material systems. However, traditional electrospinning methods struggle to meet the precision, scalability,...
Published: 4/25/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi, Ishaan Duggal
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Railroad Energy-Harvesting Tie for Powering and Charging Railway Applications
The proposed novel railroad energy-harvesting tie is capable of powering various trackside electrical and electronics equipment, including establishing remote charging stations for drones. The energy harvester tie (ETH) uses an electromagnetic generator that is coupled with an efficient motion transmission to convert the movement (kinetic energy) of...
Published: 4/4/2025   |   Inventor(s): Yu Pan, Lei Zuo, Mehdi Ahmadian
Keywords(s):  
Category(s): Technology Classifications > Engineering, Technology Classifications > Electronics, Technology Classifications > Energy
Ion-Conductive and Electron-Conductive Open Lattice Catalyst Support Framework (Case No. 2025-090)
Summary: UCLA researchers from the Department of Materials Science and Engineering have developed a novel catalyst support framework for proton-exchange membrane fuel cells. Background: Proton-exchange membrane fuel cells (PEMFCs) are promising technologies for clean energy applications due to their high efficiency and reduced emissions. These devices...
Published: 2/14/2025   |   Inventor(s): Yu Huang, Ao Zhang
Keywords(s):  
Category(s): Energy & Environment, Energy & Environment > Energy Efficiency, Materials
Advanced multi-channel controlled pneumatic printheads for 3D printing and particle fabrication
MAGIC printheads are customizable multi-channel pneumatic systems for 3D printing that create precise pharmaceutical and biological micro-particles. They enable controlled mixing and extrusion, accommodate various materials, and enhance drug delivery and biomedical applications. Background Producing micro- and nanoparticles for pharmaceutical and...
Published: 2/20/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
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