Search Results - zhengping+(ping)+zhuang

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Chemically Modified AMPA Receptor RNA Aptamers Designed for In Vivo Use

" RNA aptamers as glutamate agonists offer potential therapeutics for a range of neurological disorders RSS.HDBackground> Background: < Neurological disorders are increasingly recognized as major causes of death and disability worldwide. Nearly 500,000 cases of brain tumor, multiple sclerosis, and amyotrophic lateral sclerosis (ALS) are...

Published: 1/30/2026 | Updated: 5/13/2025 | Inventor(s): Li Niu, Zhen Huang

Keywords(s): Technologies

Category(s): Technology Classifications > Screens and Assays, Technology Classifications > Research Tools and Reagents, Campus, Campus > University at Albany

Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer

Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases, such as post-stroke cellular...

Published: 1/30/2026 | Updated: 5/13/2025 | Inventor(s): Li Niu, Zhen Huang, Yan Han, Congzhou Wang, Jae Seon Park

Keywords(s): RNA, Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus, Campus > University at Albany

Drug Candidate for ALS

RNA aptamers that focus on glutamate receptors are a potential drug candidate for amyotrophic lateral sclerosis (ALS). Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disease for which there is no cure. The disease attacks motor neurons that run from the brain to the spinal cord...

Published: 1/30/2026 | Updated: 5/13/2025 | Inventor(s): Li Niu, Zhen Huang

Keywords(s): ALS, amyotrophic lateral sclerosis, aptamers, drug design, Lou Gehrig's disease, MND, motor neurone disease, RNA

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany

Automatic System and Method for Tissue Sectioning, Staining, and Scanning

Summary: The NCI is seeking licensees to develop an automated digital pathology device compatible with high-throughput data analysis. Description of Technology: Computer and imaging technologies led to the development of digital pathology and the capture and storage of pathological specimens as digitally formatted images. The use of artificial intelligence...

Published: 4/23/2026 | Updated: 8/2/2023 | Inventor(s): Zhengping (Ping) Zhuang, Young-Wan Moon

Keywords(s): AI, Artificial Intelligence, AUTOMATION, Digital Pathology, High-throughput, Histology, IMAGING, Zhuang

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, TherapeuticArea > Neurology, TherapeuticArea > Infectious Disease, Application > Medical Devices, Application > Non-Medical Devices

Automated Digital Pathology Device for High-Throughput Demand

Published: 4/24/2026 | Updated: 7/14/2023 | Inventor(s): Zhengping (Ping) Zhuang, Young-Wan Moon, Anthony Cappadona

Keywords(s): AI, Artificial Intelligence, AUTOMATION, Digital Pathology, High-throughput, Histology, IMAGING, Zhuang

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Non-Medical Devices, TherapeuticArea > Neurology, Application > Medical Devices, TherapeuticArea > Oncology

Platform for Quantification of Transmembrane Protein Binding Kinetics

Membrane proteins, notably G-protein-couple receptors (GPCRs), are responsible for many critical cellular functions and are an important family of drug targets. Because of this, it is important to measure their binding activities with molecular ligands and drug candidates. Studying membrane proteins is challenging for two reasons. The first is...

Published: 2/26/2026 | Updated: 12/19/2022 | Inventor(s): Shaopeng Wang, Zijian Wan, Heng Zhu

Keywords(s):

Category(s): Bioanalytical Assays, Chemistries & Devices, Applied Technologies, Cancer, Imaging, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Chemical/Biological Sensors

RNA Hydrogel

Created from an RNA with unique sequence through self-assembly, this hydrogel has potential in a range of medical and research applications RSS.HDBackground> Background: < Hydrogels are water-saturated turgid materials used for a wide range of applications such as tissue engineering scaffolds and drug delivery vehicles. Hydrogels are one of...

Published: 1/30/2026 | Updated: 12/13/2021 | Inventor(s): Li Niu, Zhen Huang

Keywords(s): Technologies

Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany

Processing Technique for Ceramic- based Energy Conversion and Storage Devices

Due to rising carbon emissions, extreme weather events and other environmental threats, the demand for alternative energy sources is greater than ever. Therefore, businesses and communities are asking for three things: more affordable electricity, more resilient power, and cleaner energy. Fuel cells, electrolysis cells, membrane reactors, and solid-state...

Published: 10/27/2025 | Updated: 12/2/2020 | Inventor(s): Hai Xiao, Jianhua Tong, Fei Peng, Kyle Brinkman, Jincheng Lei, Yuzhe Hong, Hua Huang, Shenglong Mu, Rajendra Bordia

Keywords(s):

Category(s): Manufacturing

Automated Pain Detection in Pediatric Care

uot;Times New Roman",serif; font-size:12pt">Unmet Need: Continuous pain assessment in infants Continuing advances in intensive care have made it possible for premature infants to survive outside the uterus in Neonatal Intensive Care Unit (NICU) even at very early stages of development. Infants in the NICU may receive an estimated 10-14 painful...

Published: 4/8/2026 | Updated: 3/21/2019 | Inventor(s): Subhanshu Gupta, Huan Hu, Martin Schiavenato

Keywords(s):

Category(s): Technologies > Health & Well-being > Health-IT, Technologies > Health & Well-being > Medical Devices, Technologies > Energy & Environment > Computer Hardware/Software, Technologies > Energy & Environment > Electrical/Electronics

Tight Optical Integration (TOI) of Images with GPS Range Measurements [ID 09001]

OverviewThe technology is an advanced Tight Optical Integration (TOI) algorithm that integrates optical information and GPS range measurements for navigation purposes. It uses the pixel domain to represent optical information, and the range domain to represent GPS measurements. A geographic location can be determined using the information from both...

Published: 10/23/2018 | Updated: 10/23/2018 | Inventor(s): Thomas Arthur, Zhen Zhu, Sumit Bhattacharya, Maarten Uijt de Haag, Kim Michael Scheff, Kevin Johnson

Keywords(s):

Category(s): Engineering > Aerospace, Aviation & Transport, Computer Science > Software, Engineering > Electronics, Sensors & Photonics