Search Results - zijian+wan

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Label-Free Detection Platform for CircRNAs
Circular RNAs (circRNAs) hold great potential as novel biological and clinical biomarkers for diagnosis and prognosis of cancer and other diseases. Conventional detection techniques such as northern blotting, microarray, qRT-PCR and RNA-seq suffer from many issues including low sensitivity and background noise, which limit the use of circRNA in clinical...
Published: 1/19/2024   |   Inventor(s): Hao Yan, Yang Xu, Shaopeng Wang, Zijian Wan, Liangxiao Chen
Keywords(s):  
Category(s): Life Science (All LS Techs), Medical Diagnostics/Sensors, Imaging, Advanced Materials/Nanotechnology, Biomaterials, Bioanalytical Assays, Chemistries & Devices, Cancer
Platform for Quantification of Transmembrane Protein Binding Kinetics
­Membrane proteins, notably G-protein-couple receptors (GPCRs), are responsible for many critical cellular functions and are an important family of drug targets. Because of this, it is important to measure their binding activities with molecular ligands and drug candidates. Studying membrane proteins is challenging for two reasons. The first is...
Published: 2/23/2023   |   Inventor(s): Shaopeng Wang, Zijian Wan, Heng Zhu
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Applied Technologies, Cancer, Imaging, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023   |   Inventor(s): Chung-Jen (James) Chou, Ying Mei, Jia Jia
Keywords(s):  
Category(s): BioPharma