Search Results - yunlei+zhao

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Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state-of-the-art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...

Published: 6/4/2025 | Updated: 5/12/2023 | Inventor(s): Ming Xian, Hua Wang, Yu Zhao

Keywords(s): Chemistry

Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Pharmaceutical

Nanoparticle Tracking for Protein Separation and Binding Kinetics Analysis

Quantifying protein interaction kinetics is important in many biotechnology applications including biosensor development, biomarker discovery, drug screening and basic research. Current label-free techniques for quantifying protein-protein interactions often require separating the protein samples from complex media using magnetic nanoparticles....

Published: 2/26/2026 | Updated: 12/19/2022 | Inventor(s): Shaopeng Wang, Yunlei Zhao, Guangzhong Ma

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Imaging

DNA Nanocaged Enzymes

Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...

Published: 2/26/2026 | Updated: 5/10/2022 | Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao

Keywords(s): Bioanalysis, Catalysis, Enzymes

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors

Biological H2S / COS Donation by Thiocarbamates

1. Technology Overview The invention focuses on biological hydrogen sulfide (H₂S) and carbonyl sulfide (COS) donation using thiocarbamates. These compounds release COS, which is then converted to H₂S by hydrolysis or metabolism by carbonic anhydrase. The technology is currently in the development stage, with promising cross-industry applications in...

Published: 1/7/2026 | Updated: 5/2/2022 | Inventor(s): Michael Pluth, Andrea Steiger, Yu Zhao

Keywords(s):

Category(s): Chemistry, Physical Science, Therapeutics

Compounds for Thiol-Triggered COS and/or H2S Release and Methods of Making and Using the Same

1. Technology Overview The invention focuses on thiol-triggered sulfenyl thiocarbonates and sulfenyl thiocarbamates that release carbonyl sulfide (COS) and hydrogen sulfide (H₂S) in the presence of biologically relevant thiols. These compounds offer a concomitant fluorescence response, providing optical indication of COS and H₂S release. The technology...

Published: 1/2/2026 | Updated: 4/29/2022 | Inventor(s): Michael Pluth, Yu Zhao, Matt Cerda

Keywords(s): Science

Category(s): Chemistry, Engineering, Medical Devices, Physical Science, Therapeutics

Methods for Diverse Exploration in Reinforcement Learning

An autonomous system to learn how to perform a complex task from past experiences through reinforcement learning without human intervention Background: Recent advances in autonomy technology have promoted the widespread emergence of autonomous systems in various domains such as domestic robots, self-driving vehicles, and financial management...

Published: 11/12/2025 | Updated: 1/17/2020 | Inventor(s): Lei Yu, Andrew Cohen

Keywords(s): #SUNYresearch, CleanTech, Technologies

Category(s): Technology Classifications > Artificial Intelligence, Campus > Binghamton University

2015-182 FLEXIBLE BALLOON-INFLATABLE ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY TO ASSESS ENDOLUMINAL LIPID-RICH LESIONS

Case No. 2015-182SUMMARYUCLA researchers have developed a novel flexible balloon-inflatable electrochemical impedance spectroscopy to facilitate the diagnosis of metabolically active atherosclerotic lesions.BACKGROUNDIdentifying metabolically active atherosclerotic lesions remains an unmet clinical challenge during coronary intervention. Detection of...

Published: 7/17/2025 | Updated: 9/6/2019 | Inventor(s): Fei Yu, Yu-Chong Tai, Yu Zhao, Tzung Hsiai

Keywords(s): Cardiovascular, Medical Devices and Materials, Monitoring And Recording Systems

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics > Cardiovascular