Search Results - will+flanagan

38 Results Sort By:
Interactive Extended Reality Worlds with JSON Data Generated by Large Language Models
Recent LLM-XR systems mostly drive experiences by generating and compiling code on the fly. In complex scenes with thousands of artifacts and properties, models struggle to pick the right context, inflating token usage and still missing crucial constraints—like keeping cups on tables. Hallucinated or malformed scripts often fail to compile or...
Published: 1/9/2026   |   Inventor(s): Tian Lan, Bin Li, Jiangong Chen
Keywords(s):  
Category(s): Technology Classifications > Computers Electronics & Software > Artificial Intelligence, Technology Classifications > Computers Electronics & Software > Image Processing and Analysis
Tumor-pH–Triggered Doxorubicin Prodrug with On-Demand Shelf-Stable Precursor
This invention introduces a small-molecule doxorubicin prodrug that remains inert in blood and rapidly activates in the mildly acidic tumor microenvironment. Featuring a shelf-stable maleimide pre-prodrug that converts on demand to the ultra-acid-labile DMA form, it enables targeted chemotherapy with improved selectivity, scalable synthesis, and reduced...
Published: 11/12/2025   |   Inventor(s): Ming An, Lan Yao, Vladyslav Nazarenko
Keywords(s): Technologies
Category(s): Campus > Binghamton University
Small molecule sAPPalpha enhancers that inhibit brain p-Tau as a therapeutic for Alzheimer’s Disease (UCLA Case No. 2025-163)
Contact UCLA Technology Development Group to learn more.
Published: 9/18/2025   |   Inventor(s): Varghese John, Dongwook Wi, Jesus Campagna
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology
Discrete Approximation of Permanent Magnet Arrays (Case No. 2025-203)
Summary: UCLA researchers have created a cost-effective method to prototype complex magnet arrays using simple cube magnets and 3D-printed supports, enabling faster and safer development of advanced robotic, medical, and mechatronic systems. Background: Permanent magnets are widely used in mechatronic systems, such as motors, robotic grippers, medical...
Published: 12/23/2025   |   Inventor(s): Tyler Clites, He Kai Lim, Will Flanagan, Cameron Taylor
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Medical Devices, Mechanical, Mechanical > Robotics, Platforms, Platforms > Drug Delivery, Medical Devices > Medical Imaging, Life Science Research Tools, Life Science Research Tools > Research Methods
Ampule-Based Synthesis of Sulfur-Porous Carbon Composites for Lithium-Sulfur Batteries
Background Lithium/sulfur (Li/S) batteries are garnering significant attention as a promising solution for next-generation electrochemical energy storage. Their potential to revolutionize the battery industry stems from several key advantages that address the limitations of current lithium-ion (Li-ion) technology. These advantages include an exceptionally...
Published: 10/30/2025   |   Inventor(s): Yoon Hwa, David Wright, Yuhui An
Keywords(s): Chemicals, Energy storage, Engineering, Materials, Nanomaterials, Synthesis
Category(s): Energy & Power, Physical Science, Advanced Materials/Nanotechnology, Semiconductors, Materials & Processes
Beam-controlled Spectral-selective Architecture for a Radiative Cooler
This invention enhances radiative cooling of buildings by manipulating the divergent angle of thermal emission. By adjusting the direction at which heat is diverted away from buildings by this beam controlled design, the dependence of radiative cooling performance on the presence of surrounding architecture and environment can be minimized. US12352...
Published: 10/22/2025   |   Inventor(s): Qiaoqiang Gan, Lyu Zhou, Zongfu Yu, Haomin Song
Keywords(s):  
Category(s): Technology Classifications > Energy Conservation
High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases
Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...
Published: 5/27/2025   |   Inventor(s): Stephen Liggett, Donghwa Kim, Yu Chen, Jesper Madsen, Steven An
Keywords(s): Pharmaceuticals, Respiratory Diseases Treatment
Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals
Digital Twin Platform for Smart Training and Assessment in Extended Reality
The Digital Twin Platform for Smart Training and Assessment is an innovative solution that combines extended reality (XR) and artificial intelligence to revolutionize training procedures across various industries. By autonomously generating digital twins of training processes from only video inputs, the platform allows for an immersive, interactive...
Published: 1/21/2026   |   Inventor(s): Ehsan Azimi, Ruoshan Lan
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Software & Information Technology > Education & Training
S100A4 Monoclonal Antibody for Therapeutic and Diagnostic Use
Cancer metastasis are responsible for ~90% of cancer associated deaths. Recent studies suggest that immune cells play critical roles in promoting metastasis, especially myeloid cells from the bone marrow. UTHealth researchers, with researchers from Houston Methodist Hospital, observed a highly conserved expression of S100A4 in immune suppressive myeloid...
Published: 1/15/2026   |   Inventor(s): Zhiqiang An, Ningyan Zhang
Keywords(s):  
Category(s): Neurology/Neurosurgery, Oncology, Therapeutics
LILRB2 Monoclonal Antibody for Therapeutic and Diagnostic Uses of Neurodegenerative Diseases
Triggering Receptor Expressed on Myeloid cells 2 (TREM2) plays a key regulatory role in Alzheimer’s disease (AD) by controlling microglia activation and metabolic activities in brain tissues. TREM2 signaling inhibition is mediated by leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2). UTHealth inventors created and engineered...
Published: 1/15/2026   |   Inventor(s): Zhiqiang An, Ningyan Zhang
Keywords(s):  
Category(s): Neurology/Neurosurgery, Therapeutics
1 2 3 4