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Search Results - ningyan+zhang
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Antibodies against CD5L for therapeutic and diagnostic uses
Provided herein are anti-CD5L monoclonal antibodies. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer. UTHealth Ref. No.: 2020-0016 Inventors: Dr. Zhiqiang An and Dr.
Ningyan Zhang
at UTHealth; Dr. Anil Sood at UT M.D. Anderson Cancer Center Patent Status: PCT application PCT/US2021/025429...
Published: 5/28/2024
|
Inventor(s):
Zhiqiang An
,
Ningyan Zhang
,
Anil Sood
Keywords(s):
Category(s):
Biologics
,
Oncology
,
Therapeutics
Monoclonal Antibodies Against PCDH7 for Therapeutic and Diagnostic Use
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-associated deaths worldwide. UTHealth researchers discovered that the cell surface protein Protocadherin 7 (PCDH7) is highly expressed in NSCLC and promotes lung cancer development. Inventors at UTH in collaboration with Dr. O’Donnell’s group at UTSW have discovered a panel...
Published: 5/28/2024
|
Inventor(s):
Zhiqiang An
,
Ningyan Zhang
,
Kathryn O'Donnell
Keywords(s):
Category(s):
Diagnostics
,
Oncology
,
Therapeutics
,
Biologics
Monoclonal antibodies against human endotrophin for therapeutic and diagnostic use.
Background Studies have shown that endotrophin, the carboxy-terminal cleavage product of the COL6α3 chain, has potent effects on transformed mammary ductal epithelial cells in rodents. It is abundantly expressed in adipose tissue and is a chemoattractant for macrophages, exerts effects on endothelial cells and enhances the progression through...
Published: 5/2/2024
|
Inventor(s):
Zhiqiang An
,
Ningyan Zhang
,
Philipp Scherer
Keywords(s):
Category(s):
Biologics
,
Oncology
,
Therapeutics
Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer
Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. <.HDBackground>Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases,...
Published: 1/29/2024
|
Inventor(s):
Li Niu
,
Zhen Huang
,
Yan Han
,
Congzhou Wang
,
Jae Seon Park
Keywords(s):
RNA
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus
,
Campus > University at Albany
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
|
Inventor(s):
Leilei Peng
,
Yu Li
,
Han Zhang
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Medical Imaging
,
Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Novel Biofertilizer for Improving Plant Growth and Tolerance to Stress
Improved tomato root biomass after 21 days of salinity test Invention Summary: Rutgers University scientists have identified two new bacterial strains that can express 1-aminocyclopropane-1-carboxylate (ACC) deaminase, and a plant growth hormone. Its efficacy has been tested to benefit maize, tomato, and creeping bentgrass, a type of turfgrass....
Published: 9/12/2024
|
Inventor(s):
Bingru Huang
,
Ning Zhang
,
William Errickson
Keywords(s):
Biofertilizer
Category(s):
Technology Classifications > Agriculture
,
Technology Classifications > Plants, Seeds, Berries, Fruit
,
Technology Classifications > Ag Biotech
Monoclonal antibodies against human and mouse leptin for therapeutic and diagnostic use.
BackgroundLeptin is a hormone produced by adipocytes and is elevated in obesity. The congenital lack of leptin results in obesity and the metabolism field widely accepts the concept. Upon cloning of the leptin gene, the original hope was that leptin would act as a break for further food intake and a trigger to increase energy expenditure. The hope was...
Published: 5/2/2024
|
Inventor(s):
Zhiqiang An
,
Philipp Scherer
,
Ningyan Zhang
Keywords(s):
Category(s):
Biologics
,
Oncology
,
Therapeutics
,
Metabolism
HER3 specific monoclonal antibodies for diagnosis and therapeutic use
BackgroundHER-3 is a receptor in the tyrosine kinase family that is a key oncogenic protein in breast cancer as well as other cancers. HER-3 is centrally involved in signaling leading to tumor growth and has been implicated in resistance to cancer treatments, making it an attractive target for cancer therapies. Several drugs, including some in clinical...
Published: 5/2/2024
|
Inventor(s):
Zhiqiang An
,
Ningyan Zhang
Keywords(s):
Category(s):
Therapeutics
,
Diagnostics
,
Biologics
,
Oncology
Grouping Algorithm for Touchscreen Finger Position Detection (Case No. 2016-520)
Case 2016-520UCLA researchers in the Department of Electrical Engineering developed a new grouping algorithm for touchscreen finger position detection.BACKGROUNDTouchscreen technology plays an important role in the booming mobile devices market. Conventional touchscreens are designed with both horizontal and vertical electrodes. When these sensors are...
Published: 9/10/2024
|
Inventor(s):
Mau-Chung Frank Chang
,
Chunchen Liu
,
Li Du
,
Yan Zhang
Keywords(s):
Software & Algorithms
Category(s):
Software & Algorithms
,
Software & Algorithms > Programs
A Pashto-English Dictionary
This technology is a multi-use dictionary that contains Pashto entries with corresponding English words, allowing individuals to learn either Pashto or English. Background: Current versions of online Pashto dictionaries have varying amounts of Pashto entries with English translations, many of which have no verification of their learning materials,...
Published: 4/3/2023
|
Inventor(s):
Yan Han
,
Atifa Rawan
Keywords(s):
Category(s):
Technology Classifications > Creative Works
,
Technology Classifications > Software & Information Technology > Web & Internet
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