Search Results - rna+-+ribonucleic+acid

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Therapeutic Intervention for ALS and Dementia
NU 2021-058 INVENTORS Evangelos Kiskinis* Juan Alberto Ortega Cano Marco Boccitto SHORT DESCRIPTION Design of an RNA-based oligonucleotide that protects from dipeptide repeat protein toxicity for the treatment of ALS and FTD. BACKGROUND Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are devastating neurodegenerative diseases...
Published: 8/5/2025   |   Inventor(s):  
Keywords(s): ALS - Amyotrophic Lateral Sclerosis, CNS - Central Nervous System, DPR - Dipeptide Repeat Proteins, FTD - Frontotemporal Dementia, Neurodegenerative disease, Neurology, RNA - Ribonucleic Acid, Therapeutics
Category(s): Life Sciences > Therapeutics
Enhancing Gene Silencing by RNAi
NU 2005-063, NU 2005-064, and NU 2006-182 InventorsRichard Carthew* Dinari Harris Young Sik Lee Short DescriptionNovel strategy to improve gene silencing by RNAi for development of therapeutics AbstractRNAi has been proposed as a therapeutic strategy for disorders characterized by aberrant gene overexpression (cancer, macular degeneration etc.) as well...
Published: 8/5/2025   |   Inventor(s):  
Keywords(s): Biologic, Gene therapy, Infectious disease, Research tool, RNA - Ribonucleic Acid, Therapeutics, Vector/Plasmid
Category(s): Life Sciences > Therapeutics
A Novel RNA Therapeutic Candidate for Fibrotic Diseases
LU 2015-101 InventorsAnn Harris*Lindsay Stolzenburg Short DescriptionA microRNA drug candidate that treats fibrotic diseases through the repression of TGF-β receptor expression. AbstractNorthwestern researchers have identified an innovative therapeutic strategy to treat acute and chronic fibrotic diseases. Progression of fibrosis involves repeated...
Published: 8/5/2025   |   Inventor(s):  
Keywords(s): Biologic, Inflammation, RNA - Ribonucleic Acid, Therapeutics
Category(s): Life Sciences > Therapeutics