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Search Results - ftd+-+frontotemporal+dementia
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Therapeutic Intervention for ALS and Dementia
NU 2021-058 INVENTORS Evangelos Kiskinis* Juan Alberto Ortega Cano Marco Boccitto SHORT DESCRIPTION Design of an RNA-based oligonucleotide that protects from dipeptide repeat protein toxicity for the treatment of ALS and FTD. BACKGROUND Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are devastating neurodegenerative diseases...
Published: 8/5/2025
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Inventor(s):
Keywords(s):
ALS - Amyotrophic Lateral Sclerosis
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CNS - Central Nervous System
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DPR - Dipeptide Repeat Proteins
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FTD - Frontotemporal Dementia
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Neurodegenerative disease
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Neurology
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RNA - Ribonucleic Acid
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Therapeutics
Category(s):
Life Sciences > Therapeutics
ASOs targeted towards mis-spliced UNC13A
NU2022-200 INVENTORS Wanhao Chi Jonathan Watts Evangelos Kiskinis* BACKGROUND Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative that leads to 1 in 500 deaths in adults. There is no cure to stop or reverse ALS, thus there is a need to better understand its pathobiology and develop effective therapeutics. Northwestern...
Published: 8/5/2025
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Inventor(s):
Keywords(s):
FTD - Frontotemporal Dementia
Category(s):
Life Sciences > Biomarkers & Biomedical Research Tools