Search Results - next+generation+sequencing+(ngs)

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Physical Separation of Ultrashort Single-Stranded Cell-Free DNA in Biofluids Using Differential Filtration and Next-Generation Sequencing Pipeline to Detect Methylation Status of Ultrashort Single-Stranded Cell-Free DNA (UCLA 2023-077, 2023-082)
UCLA researchers in the Department of Dentistry have established novel extraction and bioinformatics pipeline of ultrashort single-stranded cell-free DNA for the use in liquid biopsy diagnostics. BACKGROUND: Liquid biopsy is a critical diagnostic tool for various human diseases. The rapid market growth of liquid biopsy is primarily driven by novel...
Published: 7/1/2024   |   Inventor(s): David Wong
Keywords(s): Cancer, cell-free DNA, circulating DNA, Diagnostic Markers & Platforms, DNA methylation, liquid biopsy, next generation sequencing (NGS)
Category(s): Software & Algorithms > Bioinformatics, Life Science Research Tools > Research Methods, Platforms > Diagnostic Platform Technologies
Swabseq Agnostic Diagnostic Platform (Case No. 2023-293)
Summary: UCLA researchers in the Departments of Computer Science and Anatomic Pathology have developed an untargeted NGS diagnostic tool capable of detecting all known and emerging respiratory RNA viruses in a single test, enhancing our capacity to rapidly address public health crises through improved diagnostics. Background: Most clinical diagnostic...
Published: 9/17/2024   |   Inventor(s): Eleazar Eskin, Valerie Arboleda
Keywords(s): agnostic detection, Bioinformatics, bioinformatics pipeline, Computer-Aided Diagnosis, Diagnostic Markers & Platforms, Diagnostic Test, DNA Sequencing, Medical diagnostics, metagenomic diagnostic platform, meta-genomics, next generation sequencing (NGS), Pathogen, Pathogenesis, Sequencing
Category(s): Platforms, Platforms > Diagnostic Platform Technologies, Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays, Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics
INTEGRATED HOST-MICROBE METAGENOMICS OF CELL-FREE NUCLEIC ACID FOR SEPSIS DIAGNOSIS
INTEGRATED HOST-MICROBE METAGENOMICS OF CELL-FREE NUCLEIC ACID FOR SEPSIS DIAGNOSIS Researchers at UCSF and the Chan Zuckerberg Institute have developed a single-sample metagenomic approach combining host transcriptional profiling with unbiased pathogen detection to improve sepsis diagnosis. Sepsis causes 20% of all deaths globally and contributes...
Published: 9/14/2023   |   Inventor(s): Charles (Chaz) Langelier, Katrina Kalantar, Lucile Neyton, Carolyn Calfee
Keywords(s): Cell-Free DNA, cfDNA, Diagnosis, Next Generation Sequencing (NGS), Sepsis
Category(s): Technology Classifications > Biology
FLASH (FINDING LOW ABUNDANCE SEQUENCES BY HYBRIDIZATION)
FLASH (FINDING LOW ABUNDANCE SEQUENCES BY HYBRIDIZATION) Researchers at the Chan Zuckerberg Biohub have developed an improved technique, FLASH, which uses a programmable nuclease to enrich target sequences during preparation of nucleotide libraries. Next generation sequencing (NGS) technology is a powerful tool in diagnostic and functional genomics....
Published: 3/17/2023   |   Inventor(s): Emily Crawford, Jenai Quan
Keywords(s): Cas9, CRISPR, Multiplex PCR, Next Generation Sequencing (NGS), Nucleic Acid Library
Category(s): Technology Classifications > Biology