Search Results - sepsis

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INTEGRATED HOST-MICROBE METAGENOMICS OF CELL-FREE NUCLEIC ACID FOR SEPSIS DIAGNOSIS
INTEGRATED HOST-MICROBE METAGENOMICS OF CELL-FREE NUCLEIC ACID FOR SEPSIS DIAGNOSIS Researchers at UCSF and the Chan Zuckerberg Institute have developed a single-sample metagenomic approach combining host transcriptional profiling with unbiased pathogen detection to improve sepsis diagnosis. Sepsis causes 20% of all deaths globally and contributes...
Published: 9/14/2023   |   Inventor(s): Charles (Chaz) Langelier, Katrina Kalantar, Lucile Neyton, Carolyn Calfee
Keywords(s): Cell-Free DNA, cfDNA, Diagnosis, Next Generation Sequencing (NGS), Sepsis
Category(s): Technology Classifications > Biology
Modulation of Leucine-rich Repeats and Calponin Homology Domain-containing Protein 4 (Lrch4) Activity for Therapeutic Applications
NIH Inventors have recently discovered a novel Leucine-rich repeat and calponin homology domain-containing protein 4 (Lrch4) in a proteomic screen of the plasma membrane of lipopolysaccharide (LPS)-exposed macrophages. Expression data by RT-PCR revealed that all Lrch family members (1-4) are expressed in macrophages, but only Lrch4 was recruited into...
Published: 10/28/2024   |   Inventor(s): Michael Fessler
Keywords(s): CB6XXX, CBXXXX, CXXXXX, DISEASES, GB1XXX, GBXXXX, GXXXXX, IB3XXX, IBXXXX, INFLAMMATORY, IXXXXX, Lrch4, Sepsis, TARGET, therapeutic
Category(s): Collaboration Sought > Collaboration, Application > Research Materials, Application > Diagnostics, Application > Therapeutics, TherapeuticArea > Oncology, TherapeuticArea > Immunology
2020-834-DEVICE FOR BLOOD PURIFICATION USING UV LIGHT SOURCE
SUMMARY: UCLA researchers in the Departments of Surgery and Bioengineering have developed a device to sterilize septic blood with ultra violet light. BACKGROUND: The overuse of antibiotics by the agricultural sector has led to an exponential rise in the number of infections that are resistant to traditional antimicrobial agents. Numerous devices...
Published: 7/19/2023   |   Inventor(s): Peyman Benharash, Vishal Dobaria
Keywords(s): Antibacterial, Antiviral Drug, Cardiovascular, Dialysis, Infection, Infectious Diseases, Intravenous Therapy, Medical Device, Sepsis, Ultraviolet
Category(s): Medical Devices, Medical Devices > Surgical Tools
Early Sepsis Detection System
Automated, Hourly, Electronic Surveillance Software Program Alerts Healthcare Providers at First Sign of SepsisThis customizable surveillance and alert software program, named Azrael, monitors all admitted hospital patients for signs of sepsis. Sepsis is a life-threatening response to an infection that can lead to tissue damage, organ failure and death....
Published: 6/27/2021   |   Inventor(s): Rhemar Esma
Keywords(s): Real-Time, Sepsis, sepsis alert, Surveillance monitoring
Category(s): Technology Classifications > Software > Healthcare IT
Photoreactor for Treatment of Jaundice
Technology Description Oregon State University is seeking a licensee or research collaborator for development or commercialization of a microfluidic visible light photoreactor for the treatment of jaundice in neonatal patients. The device enables safe extracorporeal blood treatment, making it an excellent replacement for equally effective, yet risky,...
Published: 1/16/2023   |   Inventor(s): John Lahmann, Adam Higgins
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Bilirubin, Blood, hyperbilirubinemia, light, Medical Science & Technologies, Neonatal, Newborn, Photoreactor, Sepsis, treatment
Category(s): Medical Devices, Therapeutics, Engineering