Search Results - neurons

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Prototype Software for Neuron-Centric Memory Architecture in AI (Case Nos. 2025-327/328)
Summary: Researchers at UCLA’s Department of Integrative Biology & Physiology and Neurobiology have pioneered the first prototype of a novel, neuron-centric AI architecture featuring intracellular memory and adaptive computation capabilities, designed to enhance deep learning performance and efficiency. Background: Deep learning leverages...
Published: 10/24/2025   |   Inventor(s): Alain Glanzman, David Glanzman
Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, artificial intelligence-generated content, Artificial Neural Network, Artificial Neural Network Artificial Neuron, artificial-intelligent materials, generative artificial intelligence, Medical artificial intelligence (AI), Neuron, neurons, Software, Software & Algorithms, Software Development Tools, Software-enabled learning
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical, Electrical > Computing Hardware
Broad-Band Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Neuropsychiatric Disorders (Case No. 2025-99J)
Summary: Researchers in UCLA's Semel Institute and Department of Psychiatry have developed an innovative approach to treating depression by optimizing repetitive Transcranial Magnetic Stimulation (rTMS), improving its effectiveness for the treatment of Major Depressive Disorder (MDD) and possibly diseases of the mind and brain. Background: Depression...
Published: 10/16/2025   |   Inventor(s): Andrew Leuchter, Juliana Corlier, Thomas Valles
Keywords(s): Bioelectromagnetics, Brain, Deep Brain Stimulation, Electrical Brain Stimulation, energy-efficient, frequency modulation, Magnetic Field, Medical Device, medication efficacy, neural information, neural network, neural networks, neural signals, neural stimulation, neurobehavioral impairment, Neurocognitive, neurological disorders, Neuromodulation, Neuron, neurons, neuroscience, Neurostimulation, pulsed load modulation, therapy, treatment efficacy
Category(s): Medical Devices, Medical Devices > Neural Stimulation, Life Science Research Tools, Therapeutics > CNS and Neurology, Therapeutics
Rapid and Robust Differentiation of Human iPSCs into Motor Neurons
This technology includes a system that allows for robust differentiation of human-induced pluripotent stem cells (iPSC) into motor neurons within a time frame of 7 to 10 days. To differentiate the iPSC, a stable transgene is inserted into the CLYBL safe harbor locus in the human genome using TALENs. The transgene allows for doxycycline-inducible expression...
Published: 10/28/2024   |   Inventor(s): Michael Ward, Christopher Grunseich
Keywords(s): DIFFERENTIATION, Factor-Medeated, Human, iPSC, MOTOR, Neurons, transcription, VPXXXX, WIXXXX, XEXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, Application > Research Materials
Derivatives of Docosahexaenoylethanolamide (DEA) for Neurogenesis
The invention pertains to derivatives of docosahexaenoylethanolamide (synaptamide or DEA) and their use in inducing neurogenesis, neurite growth, and/or synaptogenesis. As such, these DEA derivatives can be used as therapeutics for neurodegenerative diseases such as traumatic brain injury, spinal cord injury, peripheral nerve injury, stroke, multiple...
Published: 10/28/2024   |   Inventor(s): Erika Englund, Juan Marugan, Samarjit Patnaik, Hee-Yong Kim
Keywords(s): Derivatives, Development, Discovery, Docosahexaenoylamide, Growth, IB6XXX, IBXXXX, IXXXXX, Listed LPM Vepa as of 4/15/2015, NB1FXX, NB1HXX, NB1XXX, NBXXXX, Neurons, NXXXXX, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Promote, That, VEXXXX, YAXXXX, YBXXXX, YFXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Neurology, Application > Diagnostics, TherapeuticArea > Reproductive Health, Application > Research Materials, Application > Vaccines, Application > Therapeutics
A Nurr1-Knockout Mouse Model for Parkinson's Disease and Stem Cell Differentiation
The researchers have generated Nurr1-knockout mice via genomic locus inactivation using homologous recombination. Transcription factor Nurr1 is an obligatory factor for neurotransmitter dopamine biosynthesis in ventral midbrain. From a neurological and clinical perspective, it suggests an entirely new mechanism for dopamine depletion in a region where...
Published: 5/7/2025   |   Inventor(s): Vera Nikodem
Keywords(s): AC5XXX, ACXXXX, Affected, AS..., AXXXXX, BAXXXX, BIOSYNTHESIS, DIFFERENTIATION, Disease, Dopamine, DOPAMINERGIC, ESSENTIAL, factor, Midbrain, Neurons, NEUROTRANSMITTER, Nurr1, Obligatory, Parkinson disease 2, Parkinson disease 3, Parkinson disease 9, Parkinson disease, juvenile, autosomal recessive, Parkinsons, Region, TERMINAL, transcription, VENTRAL
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available, ResearchProducts > Animal Models