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Search Results - linxia+song
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Synthetic Viscoelastic Activating Cells (SynVACs) for T cell engineering (UCLA Case No. 2023-190)
UCLA researchers in the Department of Bioengineering have developed a novel microfluidic device that produces synthetic viscoelastic cells for efficacious therapeutic T cell activation. BACKGROUND: T cell-based therapies, such as the chimeric antigen receptor (CAR) T cell therapy, represents a significant advancement in cancer treatment, particularly...
Published: 7/19/2024
|
Inventor(s):
Zeyang Liu
,
Song Li
,
Lili Yang
,
Yan-Ruide Li
Keywords(s):
CAR-T cell therapy
,
Synthetic antigen presenting cells (SynVACs)
,
T Cell
,
T cell based therapy
,
T-cell activation
,
T-cell engineering
,
t-cells
Category(s):
Therapeutics > Oncology
Biomaterial-Based Vaccine Booster to Enhance Long-Term Immunity (UCLA Case No. 2021-170)
UCLA researchers have developed injectable, cell-free, and biomaterial-based microparticles that can engage with tissue resident immune cells and enhance long-term immunity. It is the first biomaterial-based, targeted approach to induce T memory stem cells (TMSCs) in vivo. The approach was demonstrated for SARS-CoV-2 but can be used for any vaccine....
Published: 2/26/2024
|
Inventor(s):
Mohammad Hasani-Sadrabadi
,
Song Li
,
Manish Butte
Keywords(s):
aAPCs
,
Aging
,
artificial presenting cells
,
cytokines
,
elderly
,
immunosenescence
,
microparticles
,
platform technology
,
SARS-CoV-2
,
T memory stem cells
,
TMSCs
,
Vaccines
Category(s):
Therapeutics > Infectious Diseases
,
Therapeutics > Oncology
2021-003 A Chemical Cocktail Driving Expansion of Myogenic Stem Cells
SUMMARY: UCLA researchers in the Department of Bioengineering have developed a novel chemical cocktail for enhancing myogenic stem cell expansion both in vitro and in situ that could lead to more affordable and faster development of stem cell-based therapies and chemical delivery technologies for muscle regeneration. BACKGROUND: Skeletal muscle tissue...
Published: 8/25/2023
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Inventor(s):
Song Li
Keywords(s):
Category(s):
Therapeutics
,
Therapeutics > Musculoskeletal Disease
Self-neutralizing air-breathing thruster and method of neutralization
An ion-engine is the cutting edge for atmospheric air-breathing engines. The technology depends on ionizing and neutralizing atmospheric air particles which create thrust. This unique possibility makes it an ideal choice for very-low-orbit satellites. Very- low-orbit satellite capabilities have benefits such as higher resolution for images, weight...
Published: 7/30/2024
|
Inventor(s):
Michael Keidar
,
Anmol Taploo
,
Li Lin
Keywords(s):
Category(s):
Technology Classifications > Computers Electronics & Software
,
Technology Classifications > Computers Electronics & Software > Aviation
,
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
,
Technology Classifications > Industrial or Consumer Tech > Industrial Manufacturing
Intelligent Multi-Beam Medium Access Control in Ku-Band for Mission-Oriented Mobile Mesh Networks
The Problem: There are existing similar technologies, but these technologies are not designed for mobile mission-oriented applications. The use of Ku-band frequency on two separate information transmission levels reduces interference common with current multi-beam antennas. Also, the Ku-band frequency is not the currently used frequency range...
Published: 2/27/2023
|
Inventor(s):
Fei Hu
,
xI Li
,
Sunil Kumar
Keywords(s):
Category(s):
Technology Classifications > Communication
High-Frequency Mist Generation for Bio and Non-Bio Molecular Ionization under Ambient Condition
Competitive Advantages High and temperature resistant survival yield Lowest limits of detection to date in direct mass spectrometry methods Low-cost, durable design with easily sourced elements Summary USF inventors have coupled an ultrasonic piezo that is originally designed as a room humidifier, termed ultrasonic nebulizer, with...
Published: 7/18/2023
|
Inventor(s):
Theresa Evans-Nguyen
,
Linxia Song
,
Yi You
Keywords(s):
Health Tech
,
Medical Diagnostics
,
Research Tools
Category(s):
Technology Classifications > Electronics > Food Sciences
,
Technology Classifications > Electronics
Immunoactive Microparticles and Uses Thereof (UCLA Case No. 2020-200)
SUMMARY: UCLA Researchers from the division of Immunology in the David Geffen School of Medicine have developed an improved method of stimulating anti-tumor T-cells for use in cancer immunotherapy. BACKGROUND: Cancer immunotherapy, a therapeutic strategy whereby a patient’s own immune system is reequipped to attack cancer cells, promises more...
Published: 4/9/2024
|
Inventor(s):
Manish Butte
,
Mohammad Hasani-Sadrabadi
,
Fatemeh Sadat Majedi
,
Song Li
Keywords(s):
Category(s):
Therapeutics > Immunology And Immunotherapy
,
Therapeutics > Oncology
,
Therapeutics > Oncology > Oncology Immunotherapy
,
Materials > Nanotechnology
Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors
Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...
Published: 7/30/2024
|
Inventor(s):
Michael Keidar
,
Li Lin
,
Vikas Soni
,
Xiaoliang Yao
,
Dayun Yan
,
Jonathan Sherman
Keywords(s):
Category(s):
Technology Classifications > Medical Devices
,
Technology Classifications > Medical Devices > Surgical
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
|
Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Cold atmospheric plasma-stimulated media for treating cancers
For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...
Published: 7/30/2024
|
Inventor(s):
Michael Keidar
,
Zhitong Chen
,
Xiaoqian Cheng
,
Li Lin
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Cells
,
Technology Classifications > Therapeutics
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