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Methods and Sequences for mRNA and Other HIV Vaccine Development
Unique sequences eliciting broadly neutralizing antibodies (bNAbs) against human immunodeficiency virus (HIV) that could be used to develop effective mRNA-based and other types of HIV vaccine.
Problem:
Despite decades of research, there is currently no vaccine to prevent HIV infection. A major goal of HIV vaccine programs is to generate bNAbs, which...
Published: 3/31/2025
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Inventor(s): George Shaw, Edward (Ted) Kreider, Beatrice Hahn, Ashwin Skelly, Hui Li, Drew Weissman
Keywords(s): Bioengineering, HIV/AIDS, Immunology, Infectious Disease, Protein/Peptide (Non-Antibody)
Category(s): Technology Classifications > Vaccines
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Two Compartment Model for Detecting the Toxicity of Liver Metabolites
Overview
Liver toxicity is a significant reason many new drugs fail in clinical trials. Primary human hepatocytes (PHHs) are the current gold standard for in vitro liver models; however, they have a number of limitations. We have invented an easy-to-use two-compartment device that provides in vitro 3D high-throughput prediction for safety assessments...
Published: 3/5/2025
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Inventor(s): Kim Boekelheide, Jeffrey Morgan, Blanche Ip, Susan Hall, Hui Li
Keywords(s):
Category(s): Diagnostics
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ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING
ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING
Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording.
EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...
Published: 1/31/2025
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Inventor(s): Ada Poon, Cheng Chen, Joonseok Yang, Hui Wang
Keywords(s): EEG, Neurology, Wearable
Category(s): Technology Classifications > Engineering
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Lithium selective organogels
Background
Lithium (Li) is a highly reactive alkali metal with excellent heat and electrical conductivity properties, making it useful for a variety of industrial applications. Because of Li’s high reactivity, pure elemental Li is not found in nature but is present as a constituent of salts or other compounds found in brines, mineral ores, clays,...
Published: 12/11/2023
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Inventor(s): Jonathan Sessler, Zachariah Page, Hu Wang
Keywords(s):
Category(s): Physical sciences > Materials, Physical sciences > Energy > Renewable, Life sciences > Research tools > Tool/assay/screening platform, Physical sciences > Energy > Battery or electrochemical
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New Method to Produce PBI Films without using Organic Solvents
Reference #: 01429
The University of South Carolina is offering licensing opportunities for New Method to Produce PBI Films without using Organic Solvents
Background:
Polybenzimidazole Film is used in membrane electrode assemblies for fuel cells, flow batteries, and hydrogen pumps. The PBI film is a separator between a nickel mesh and carbon felt....
Published: 3/4/2025
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Inventor(s): Brian Benicewicz, Fei Huang, Lihui Wang, Laura Murdock
Keywords(s): Film, Gel membrane, PBI, Polybenzimidazole, PPA Process, solvent-free
Category(s): Engineering and Physical Sciences
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PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 2/18/2025
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Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
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Targeting Treatment For ADAM30 In Pathological Cells
Reference #: 01462
The University of South Carolina is offering licensing opportunities for Targeting treatment for ADAM30 in pathological cells
Background:
The treatment options for vascular malformations include conservative management, drug treatment, interventional radiology, laser therapy, excisional surgery and psychological treatment. However,...
Published: 9/3/2024
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Inventor(s): Wenbin Tan, Elaine Taine, Hui Wang, Vi Nguyen, Xialing Cao
Keywords(s): a disintegrin and metalloprotease (ADAM), antibody, biomarker, cancer, inhibitor, vascular malformation
Category(s): Health Sciences, Biomedical and Life Sciences
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Thiadiazine Kinase Inhibitors
Thank you for your interest in this technology. Please see our technology brief here: https://app.in-part.com/articles/Mk10MZPK7vJj
Published: 10/23/2024
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Inventor(s): Robert Devita, Andrew Stewart, Avner Schlessinger, Kunal Kumar, Peter Ung, Hui Wang, Hailing Li
Keywords(s):
Category(s): Therapeutic
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TRIPLE ON-BOARD IMAGER FOR RADIATION THERAPY
An invention to increase the target accuracy of radiation therapy and improve cancer treatment. The InventionThe invention is an integrated gantry-based triple on-board imager (OBI) into medical linear accelerator (Linac) for human image-guided radiation therapy (IGRT) that allows functional and molecular imaging and treatment to take place in the same...
Published: 1/13/2025
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Inventor(s): Yu Kuang, Hui Wang
Keywords(s):
Category(s): Technology Classifications > Medical Devices
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Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
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Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert
Keywords(s):
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources
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