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Reagent Molding Process for Point of Care Microfluidic Applications

Invention Description Lyophilization is a critical process for stabilizing reagents in point-of-care (POC) diagnostics, effectively eliminating the need for cold chain storage and preventing liquid evaporation. While this technology is essential for developing robust field-deployable devices, current industry standards are limited to producing reagents...

Published: 1/26/2026 | Inventor(s): Jennifer Blain Christen, Vi Nguyen

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care

User-Actuated Valve Actuator for Microfluidic Devices

Invention Description Lab-on-a-chip technology and microfluidic diagnostic devices often rely on complex mechanical or electrical systems to manipulate fluid, making them costly and bulky. These components may limit portability, decrease operational lifetime, and prevent widespread use by untrained personnel or patients at the point of care or at home....

Published: 1/12/2026 | Inventor(s): Clifford Anderson, Vi Nguyen, Jennifer Blain Christen

Keywords(s): Analytical Devices, Bioassay, Biosensor, Fluid, Micro-Fluidics

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Point of Care

Integrated Microfluid Cartridge for POC Biofluid Diagnostics

Invention Description Rapid and reliable nucleic acid assays are critical for diagnosing infectious diseases at the point of need, yet most systems rely on complex, expensive instrumentation and trained personnel. These requirements limit access to timely diagnostics in low-resource, remote, or decentralized settings. Many platforms typically require...

Published: 1/6/2026 | Inventor(s): Vi Nguyen, Clifford Anderson, Jennifer Blain Christen

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Coronavirus, COVID-19, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care, SARS-CoV-2

Microfluidic Device Design for Point-of-Care Devices

Implementing liquid-based assays, such as PCR and LAMP, is difficult in POC microfluidic devices, due to bubble formation. To mitigate this, auxiliary metering systems or actuators are required to regulate consistent flow rates. This can make the microfluidic device more complicated to operate, increases cost, and limits rapid prototyping, ultimately...

Published: 9/29/2025 | Inventor(s): Vi Nguyen, Jennifer Blain Christen

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Diagnostics/Sensors, Genomic Assays/Reagents/Tools

Drug repurposing for treatment of congenital vascular malformations

Reference #: 1659 The University of South Carolina is offering licensing opportunities for Drug Repurposing for Treatment of Congenital Vascular Malformations. Background: Congenital vascular malformations (CVM) are a major threat to public health with a 1.5% incident rate in the general population. Congenital capillary malformation (CM), a.k.a.,...

Published: 12/3/2025 | Inventor(s): Wenbin Tan, Vi Nguyen, Chao Gao, Anil Jegga, Yunguan Wang, Sudhir Ghandikota, Marcelo Hochman

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Trigonelline mitigates cardiomyopathy caused by SARS-CoV-2 Spike protein under obesity

Reference #: 01642 The University of South Carolina is offering licensing opportunities for Trigonelline mitigates cardiomyopathy caused by SARS-CoV-2 spike protein under obesity. Background: Today, the spread of Coronavirus Disease 2019 (COVID-19) continues, and while millions of patients have recovered, a significant number experience prolonged...

Published: 5/17/2024 | Inventor(s): Wenbin Tan, Vi Nguyen, Taixing Cui

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Category(s): Health Sciences, Biomedical and Life Sciences

Retinol Acid Pathway Modulators for Treatment of Congenital Vascular Malformation

Reference #: 01657 The University of South Carolina is offering licensing opportunities for Retinol Acid Pathway Modulators for Treatment of Congenital Vascular Malformation. Background: Congenital vascular malformations (CVM) are a major threat to public health with a 1.5% incident rate in the general population. Congenital capillary malformation...

Published: 12/3/2025 | Inventor(s): Wenbin Tan, Vi Nguyen, J. Stuart Nelson

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Category(s): Biomedical and Life Sciences

Targeting Treatment For ADAM30 In Pathological Cells

Reference #: 01462 The University of South Carolina is offering licensing opportunities for Targeting treatment for ADAM30 in pathological cells Background: The treatment options for vascular malformations include conservative management, drug treatment, interventional radiology, laser therapy, excisional surgery and psychological treatment. However,...

Published: 9/3/2024 | Inventor(s): Wenbin Tan, Elaine Taine, Hui Wang, Vi Nguyen, Xialing Cao

Keywords(s): a disintegrin and metalloprotease (ADAM), antibody, biomarker, cancer, inhibitor, vascular malformation

Category(s): Health Sciences, Biomedical and Life Sciences