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Search Results - iluppangama+iluppangama
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ERG-7 Inhibitors: Targeting the Sterol Biosynthetic Pathway
This invention relates to small molecule anti-fungal compounds, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of fungal diseases in human and veterinary subjects. In particular aspects, the invention provides inhibitors that modulate fungal sterol biosynthesis, including inhibitors of lanosterol synthase...
Published: 5/6/2026
|
Updated: 5/6/2026
|
Inventor(s):
Rui Xiong
,
Hongmin Li
,
Malla Reddy Gannarapu
,
Divakar Indukuri
,
Anil Tharappel
,
Ke Chen
,
Mengjiao Ma
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Infectious Diseases
,
Technology Classifications > Healthcare Portfolios > Neurology
,
Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
,
Technology Classifications > Life Sciences > Small Molecules
,
Technology Classifications > Life Sciences > Therapeutics
nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 4/29/2026
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Updated: 4/29/2026
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Inventor(s):
Hongmin Li
,
Rui Xiong
,
Subodh Samrat
,
Malla Reddy Gannarapu
,
Ran Zhang
,
Ke Chen
,
Mengjiao Ma
,
Omar Alejandro Lozano Ramos
,
Divakar Indukuri
,
Renu Bhardwaj
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Infectious Diseases
,
Technology Classifications > Life Sciences > Therapeutics
,
Technology Classifications > Life Sciences > Small Molecules
Neutralizing Monoclonal Antibodies Against West Nile Virus
West Nile virus (WNV) is a mosquito-borne flavivirus that can cause fever and, in some cases, severe neurologic disease. There is no approved human vaccine or specific antiviral treatment for WNV. Researchers at NIAID's Vaccine Research Center (VRC), working with collaborators at Sheba Medical Center under the PREMISE program, identified...
Published: 4/24/2026
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Updated: 4/24/2026
|
Inventor(s):
Daniel Douek
,
Chaim Schramm
,
Ananda Chowdhury
,
Parker Dabbs
,
Lu Wang
,
Leonid Serebryannyy
,
Theodore Pierson
,
Kimberly Dowd
,
Laura Vanblargan
,
Katherine Burgomaster
,
David Gordon
,
Yuxiang Wang
,
Yaniv Lustig
,
Yael Ottolenghi
,
Dror Harats
,
Sarah Smith (Kerscher)
Keywords(s):
Category(s):
Application
,
ResearchProducts > Virus/Bacteria
,
ResearchProducts
,
ResearchProducts > Antibodies
,
TherapeuticArea
,
Application > Diagnostics
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 5/1/2026
|
Updated: 3/23/2026
|
Inventor(s):
Alex McGhee
,
Kelvin Pond
,
A Departmental Work
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Sensors and Detection
,
Technology Classifications > Engineering & Physical Sciences > Photonics
,
Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
,
Technology Classifications > Life Sciences > Diagnostics
,
Technology Classifications > Research Tools > Screening assays
GENERATOR FOR WAVE ENERGY HARVESTING
VAlue proposition Ocean wave energy has many advantages like high power density, wide distribution, ease in harvesting and independence of time of day, weather or seasons. It is estimated that the global power by waves breaking around the coastlines worldwide is around 2–3 TW. However, ocean renewable energy technologies like wave energy converters...
Published: 3/12/2026
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Updated: 3/12/2026
|
Inventor(s):
Changyong Cao
,
Yaokun Pang
Keywords(s):
Category(s):
Energy
,
Environmental
Aptamer-based field diagnostics for infectious PRRSV and PEDV detection
Background Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Porcine Epidemic Diarrhea Virus (PEDV) are two of the most economically destructive viruses impacting the global swine industry. These pathogens cause severe illness and death in pig populations, leading to reduced productivity, increased veterinary expenses, and trade restrictions....
Published: 3/11/2026
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Updated: 3/11/2026
|
Inventor(s):
Yi Lu
,
Whitney Lewis
Keywords(s):
Category(s):
Life sciences > Agriculture > Animal/veterinary
,
Life sciences > Diagnostic
System For Applying Therapy To the Human Body
RPI ID: 2022-038-201 Innovation Summary: A therapeutic system is disclosed that includes a coupling apparatus and a supporting apparatus designed to apply spinal traction while the user is in a seated position. The coupling apparatus attaches to the upper body using components such as a vest, belt, or harness, while the supporting apparatus—such...
Published: 3/10/2026
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Updated: 3/10/2026
|
Inventor(s):
Michael Castello
,
Ryan Chien
,
Jeongwon Choi
,
Ruiqi Ma
,
Jacqueline Ray
,
Eric Ledet
Keywords(s):
Category(s):
Nanotechnology and Advanced Materials
Student Outcomes & Predictions in Higher Education using Artificial Intelligence (SOPHEA-I )
RPI ID: 2021-021-401 Innovation Summary: A predictive analytics system uses student data to forecast retention rates across academic programs. The model incorporates behavioral, demographic, and performance metrics to identify at-risk students. Machine learning algorithms continuously refine predictions based on new inputs. The system supports institutional...
Published: 3/10/2026
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Updated: 3/10/2026
|
Inventor(s):
Jasmine Yang
,
Lu Enzhe
,
Jiarun Li
,
Yihui Yang
,
Hui Su
,
Yifan Liu
,
Keith Moo-Young
Keywords(s):
AI
,
machine-learning
,
Student Persistent and success
Category(s):
Media, Arts, Science and Technology
A novel synthetic constitutive-active glucocorticoid receptor
Introducing "superGR," a novel synthetic glucocorticoid receptor fusion protein designed to enhance glucocorticoid therapy by providing ligand-independent activation and improved gene regulation for inflammatory diseases. Background: Glucocorticoids are widely used to treat inflammatory conditions like severe alcoholic hepatitis and sepsis,...
Published: 3/9/2026
|
Updated: 2/19/2026
|
Inventor(s):
Hong Lu
,
Conor Fahy
Keywords(s):
gene therapy
,
glucocorticoid
,
inflammatory liver disease
,
lung injury
,
sepsis
,
synthetic materials
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Biomedical Science and Engineering
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026
|
Updated: 2/9/2026
|
Inventor(s):
A Departmental Work
,
Michael Brown
Keywords(s):
Category(s):
Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
,
Technology Classifications > Research Tools
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