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Machine-learning guided engineering of T7 RNA polymerase and mRNA capping enzyme for enhanced gene expression in eukaryotic systems
This technology uses machine learning to engineer improved enzymes that dramatically boost gene expression in eukaryotic cells, enabling more efficient production of mRNA, proteins, and therapeutics for research, industrial, and medical applications. Background The field of eukaryotic gene expression is foundational to biotechnology, synthetic biology,...
Published: 7/10/2026   |   Updated: 7/10/2026   |   Inventor(s): Andrew Ellington, Daniel Diaz, Seunggyun Woo, Wantae Kim, Kaci Erwin, Ilya Finkelstein, Chien-Hui Ma, Do-Wook Kim
Keywords(s):  
Category(s): Life sciences > Research tools > Reagent, Life sciences > Therapeutics > Gene therapy