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Enhancing Urban UAV Operations with Multi-Dimensional Fiducial Markers for Safety, Security, and Adaptability
Invention Description UAVs rely on fiducial markers, such as AprilTag or Aruco, to help with navigation and precision landing under GPS-denied environments. However, these markers are facing significant limitations in dense urban environments from adverse weather conditions, low visibility, urban clutter as well as security risks from tampering. These...
Published: 1/13/2026   |   Inventor(s): Dajiang Suo, Manuel Garcia, Marco Vincenzi, Shaozu Ding
Keywords(s):  
Category(s): Cybersecurity, Physical Science, Intelligence & Security, Applied Technologies, Wireless & Networking
Small Molecules That Expose HIV Env Sites To Trigger Targeted Immune Killing
This technology uses small molecules to bind HIV Env on infected cells, expose hidden sites, and trigger ADCC, enabling the immune system to kill cells that current therapies cannot reach. By improving antibody recognition and reducing infectious virus production, it provides a complementary approach that directly targets infected cells rather than...
Published: 12/1/2025   |   Inventor(s): Amos Smith, Melissa Grenier-Davies, Andres Finzi, Jean-Philippe Chapleau, Shilei Ding
Keywords(s): HIV/AIDS
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Vaccines
A Potent HIV Treatment with Low Toxicity
A small-molecule class that binds to HIV particles to improve immune response and block viral entry into cells. Problem: 37 million people worldwide currently live with HIV and an estimated 2-3 million new infections occur annually. While antiretroviral therapies do exist for those with the disease, therapy interruption leads to the re-emergence of...
Published: 11/11/2025   |   Inventor(s): Amos Smith, Xuchen Zhao, Tyler Higgins, Andres Finzi, Shilei Ding, Daniel Lee, Marzena Pazgier, Dung Nguyen, William Tolbert
Keywords(s): Drug Target, HIV/AIDS, Small Molecule, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics
Aeroacoustic Duster
Precision particle removal from a surface with no physical contact using a bounded vortex and peripheral jets providing streamlines Background: Mitigation of dust or particle build up on surfaces is a problem in many industries, especially where the surface being cleaned cannot be damaged, such as optical materials or delicate electronic instruments....
Published: 7/9/2025   |   Inventor(s): Jeffrey Marshall, Darren Hitt, Di Chen, Jun-Ru Wu, Nicholas Vachon
Keywords(s):  
Category(s): Technology Classifications > Engineering
DNA/RNA Origami Assembly Mediated by Functional Peptides
DNA and RNA nanostructures, e.g., DNA Origami, have great potential in biological applications, including extracellular matrix scaffolds and delivery vehicles for drugs and gene therapies. While folding DNA origami under physiological conditions is plausible, significant challenges and limitations remain. For example, isothermal annealing of DNA origami...
Published: 4/2/2025   |   Inventor(s): Di Liu, Bing Xu, Zhishang Li, Jiaqi Guo
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biological Nanotechnology, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Nucleic Acid/Peptide/Protein Therapies
Cyanobacterial Hosts and Methods for Producing Structurally Diverse Chemicals
Engineered Cyanobacterial System for the Production of Natural Products Such as ShinorineThis genetically modified cyanobacterial host system uses Synechocystis as the host bacteria to produce structurally diverse natural products. Cyanobacterial natural products and their analogs are useful chemicals in health, agriculture and other industries. While...
Published: 1/20/2026   |   Inventor(s): Guang Yang, Yousong Ding
Keywords(s): Chemical, cyanobacterial, host development, precursor, Production, secondary metabolites
Category(s): Technology Classifications > Others > Others
Treating Age-Related Hearing Loss with Rapamycin and Its Derivatives
Advantages: Novel Application of FDA approved drugs, rapamycin and its derivatives, for treating age-related hearing loss (ARHL). Targeting mTOR alleviates oxidative stress and inflammation in the cochlea, enhancing cellular health and resilience to age-related damage. Potential to Reverse or Delay Age-related hearing loss (ARHL) in patients. Summary: Age-related...
Published: 1/17/2025   |   Inventor(s): Robert Frisina, Xiaohua Zhu, Bo Ding, Xiaoxia Zhu
Keywords(s): Pharmaceuticals, Therapeutics
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices
Iridium-based Integrated Electrode for Solid Polymer Electrolyte Electrolyzer Cell System
Proton Exchange Membrane Electrolyzer Technologies From the EESC Lab Hydrogen power is one of several forms of energy expected to play a major role in a sufficiently advanced de-carbonized energy system, with electrolysis being a promising route for the green production of hydrogen from renewable energy sources. Among various other electrolyzer technologies,...
Published: 6/7/2024   |   Inventor(s): Feng Yuan Zhang, Lei Ding, Kui Li, Weitian Wang
Keywords(s):  
Category(s): Chemistry & Materials
Human Serum Albumin-Transgenic Mouse
A novel human albumin transgenic mouse model was developed which can be used to establish human protein biomarkers of exposure to hazardous xenobiotics for human risk assessment via animal studies. This can provide a unique in vivo tool for the assessment of risks of toxicity associated with human exposure to environmentally hazardous chemicals and...
Published: 1/28/2026   |   Inventor(s): Xinxin Ding
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Life Sciences
Molecular Imaging of the Cochlea
­Advantages: Enhanced microenvironment sensitivity and detailed structural insights enabled by use of Thallium-201 (201TI) Precise treatment response tracking through measurement of ionic concentration changes through quantification of potassium changes Non-invasive, patient friendly approach for auditory assessment Summary: Assessing...
Published: 1/12/2026   |   Inventor(s): Parveen Bazard, Mikalai Budzevich, Xiaoxia Zhu, Bo Ding, Robert Frisina
Keywords(s): Diagnostics, Medical Imaging
Category(s): Technology Classifications > Medical > Medical Imaging, Technology Classifications > Medical > Medical Diagnostics
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