Search Results - hongxu+ding

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An Iterative Approach to Polish the Nanopore Sequencing Basecalling for Therapeutic RNA Quality Control
This invention is an improvement of nanopore sequencing base calling accuracy via an iterative approach using existing machine learning algorithms and alignment with ground-truth references. This new method allows base calling accuracy to improve as the technology is trained, which in turn creates countless opportunities for sequencing improvement in...
Published: 5/30/2025   |   Inventor(s): Hongxu Ding
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Vaccines, Technology Classifications > Life Sciences > RNAi/siRNA, Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Software & Information Technology > Health IT
Telecentric and Broadband Achromatic Objective Lens Systems
Achromatic lens systems with telecentric objectives enhance precision in optical coherence tomography for freeform surface metrology Institute Reference: 2-18091 Background Freeform optical components provide high performance but are challenging to measure with low uncertainty due to their complex shapes. Conventional metrology tools like Optical...
Published: 10/21/2024   |   Inventor(s): Jannick Rolland-Thompson, Di Xu, Romita Chaudhuri
Keywords(s):  
Category(s): Imaging, Optics, Devices
Cascade Fourier Domain Optical Coherence Tomography
Advanced OCT system using cascaded interferometers for precise, non-contact measurement of complex freeform optical surfaces Institute Reference: 2-18049 Background High-precision optical metrology is essential for ensuring surface accuracy, particularly in advanced optics manufacturing, where tolerances can reach sub-nanometer scales. Modern optical...
Published: 10/21/2024   |   Inventor(s): Jannick Rolland-Thompson, Di Xu
Keywords(s):  
Category(s): Optics
Two-terminal multicolor photo-detectors (PD) and focal plane arrays (FPA)
The state of the art of two-color focal plane arrays (FPAs) are two or three terminal photo detector pixels integrated with electronic readout circuits (ROICs). However, a multicolor (> 2) photodetector pixel requires many more terminals, making it very difficult, if not impossible, to integrate multicolor pixel arrays to ROICs due to the increase...
Published: 2/13/2025   |   Inventor(s): Yong-Hang Zhang, Ding Ding, Elizabeth Steenbergen
Keywords(s):  
Category(s): Physical Science, Semiconductor Devices