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Large-Scale Production of Pharmaceutically Essential Nitroaromatics Using Non-Toxic Biocatalysts
Does Not Use Nitric Acid, Eliminates Environmental and Safety Hazards Associated With Production of Nitroaromatics This nitration system produces large quantities of pharmaceutically relevant nitrated tryptophan and other nitroaromatics using biocatalysts. Nitrated tryptophan and other nitroaromatics are essential components of a wide variety of pharmaceuticals,...
Published: 9/7/2022   |   Inventor(s): Yousong Ding, Ran Zuo
Keywords(s):  
Category(s): Technology Classifications > Engineering, Technology Classifications > Engineering > Chemical
Glycan Binding Protein Can Detect, Isolate, and Purify Therapeutic Proteins and Antibodies
Glycan Binding Protein Derived from Common, Inexpensive Mushrooms The recombinant glycan-binding protein Ab-Y3, found in an edible, common mushroom, is useful for detecting, isolating, purifying, and screening proteins with specific N-glycans of medical significance, such as immunoglobins or IgG proteins. Glycan binding proteins are critical for a...
Published: 9/7/2022   |   Inventor(s): Yousong Ding, Steven Bruner, Peilan Zhang, Brian MacTavish
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Biological Materials
Multicellular Living Drug Platform for Targeted Treatment of Various Diseases
Isolated Micro-Ecosystems Secrete Drug Molecules at Controlled Doses and Locations This drug platform employs living multicellular assemblies that can deliver drug molecules in controlled patterns to specific tissues in order to perform complex therapeutic functions. Unlike standard small-molecule drugs and biopharmaceuticals, living drugs are therapeutic...
Published: 11/18/2021   |   Inventor(s): Yunwei Cao, Tianyuan Xiao, Shouguang Jin, Yousong Ding
Keywords(s):  
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Research Tools > Therapeutics
Cyanobacterial Hosts and Methods for Producing Structurally Diverse Chemicals
Engineered Cyanobacterial System for the Production of Natural Products Such as ShinorineThis genetically modified cyanobacterial host system uses Synechocystis as the host bacteria to produce structurally diverse natural products. Cyanobacterial natural products and their analogs are useful chemicals in health, agriculture and other industries. While...
Published: 6/27/2021   |   Inventor(s): Yousong Ding, Guang Yang
Keywords(s): Chemical, cyanobacterial, host development, precursor, Production, secondary metabolites
Category(s): Technology Classifications > Others > Others
Biocatalysts for Generating Nitroaromatics in an Environmentally-Friendly Manner
Efficient, Environmentally Sustainable Approach for Aromatic NitrationThese biocatalysts can generate novel nitroaromatic end products and building blocks for the synthesis of more complex compounds in an environmentally friendly manner. Nitro aromatic and heterocyclic derivatives are important industrial chemicals that are used as food additives, pesticides,...
Published: 11/19/2021   |   Inventor(s): Yousong Ding
Keywords(s): catalyst, direct nitration, enzyme process, P450, Research Tool, self-sufficient
Category(s): Technology Classifications > Research Tools > Others
Two-terminal multicolor photo-detectors (PD) and focal plane arrays (FPA)
The state of the art of two-color focal plane arrays (FPAs) are two or three terminal photo detector pixels integrated with electronic readout circuits (ROICs). However, a multicolor (> 2) photodetector pixel requires many more terminals, making it very difficult, if not impossible, to integrate multicolor pixel arrays to ROICs due to the increase...
Published: 2/23/2023   |   Inventor(s): Yong-Hang Zhang, Ding Ding, Elizabeth Steenbergen
Keywords(s):  
Category(s): Physical Science, Semiconductor Devices