Search Results - chemical

16 Results Sort By:
Identification and Use of a Novel Functionally Selective GHSR1a Ghrelin Receptor Inhibitor, including NCGC00538279, for the Treatment of Food and Chemical Addiction
This technology includes a chemical series, including the NCGC00538279 compound, that selectively activates the GHSR1a G-protein pathway for calcium mobilization while only partially activating the beta-arrestin-2 translocation pathway. The resulting chemical series may be therapeutically valuable for addictive disorders. Activation of the GHSR1a G-protein...
Published: 7/25/2024   |   Inventor(s): Noel Southall, Marc Ferrer-Alegre, Daniel Jansen, Mark Henderson, Xin Hu, David Kim, Juan Marugan
Keywords(s): ADDICTION, Chemical, FOOD, Funtionally, Ghrelin, LIGAND, NCG00538279, Novel, RECEPTOR, SELECTIVE, treatment, VEXXXX, VGXXXX, WIXXXX, WKXXXX, XEXXXX
Category(s): TherapeuticArea > Neurology, Application > Therapeutics, TherapeuticArea > Endocrinology, Application > Research Materials
High Voltage Redox Electrolytes for Enhanced Electrochemical Capacitor Performance and Reduced Self-Discharge
Researchers have created a hybrid device that combines the advantages of both batteries and supercapacitors. Background Supercapacitors and batteries are the two leading forms of electrochemical energy storage. Both have unique advantages and can be applied to various applications. Supercapacitors can be charged quickly resulting in very high...
Published: 5/4/2022   |   Inventor(s): Shannon Boettcher, Galen Stucky, Brian Evanko, Nicholas Parker, David Vonlanthen, David Auston, Sang-Eun Chun, Xiulei Ji, Bao Wang, Xingfeng Wang, Raghu Subash Chandrabose
Keywords(s): Advanced Materials, Chemical, Electrochemistry, Inorganic, Materials Science
Category(s): Chemistry, Engineering, Materials Science, Nanoscience & Microtechnologies, Physical Science, Sustainability & Cleantechnologies
2021-355 Magnetically Activated Individual Cell Sorting Using Spin Orbit Torque
SUMMARY: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a magnetically activated cell sorting method with high throughput and low-cost operation. BACKGROUND: The use of cell sorting techniques has become indispensable for many applications in biology and biomedicine. Cell sorting is particularly important...
Published: 7/19/2023   |   Inventor(s): Abdon Sepulveda, Victor Estrada, Ruoda Zheng, Yilian Wang
Keywords(s): Cancer Immunotherapy, Chemical, Diagnostic Markers & Platforms, High-Throughput Screening, Imaging, Magnetic Field, Materials, Nanomaterials, Nanotechnology, T Cell
Category(s): Life Science Research Tools > Microscopy And Imaging, Materials > Nanotechnology, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Cell Counting And Imaging, Medical Devices > Medical Imaging
Cyanobacterial Hosts and Methods for Producing Structurally Diverse Chemicals
Engineered Cyanobacterial System for the Production of Natural Products Such as ShinorineThis genetically modified cyanobacterial host system uses Synechocystis as the host bacteria to produce structurally diverse natural products. Cyanobacterial natural products and their analogs are useful chemicals in health, agriculture and other industries. While...
Published: 6/27/2021   |   Inventor(s): Yousong Ding, Guang Yang
Keywords(s): Chemical, cyanobacterial, host development, precursor, Production, secondary metabolites
Category(s): Technology Classifications > Others > Others
2020-408: sAPPalpha Targeted Therapeutics for Alzheimer’s Disease
UCLA researchers from the Department of Neurology have developed a novel application of two compounds that target the upstream formation of toxic amyloid-beta oligomers for the effective treatment of Alzheimer’s disease. BACKGROUND: Alzheimer’s Disease (AD) is the most common age-related neurodegenerative disorder currently affecting ~6...
Published: 7/19/2023   |   Inventor(s): Varghese John, Sujyoti Chandra
Keywords(s): Chemical, Cns, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > CNS and Neurology
2020-478 CONVERSION OF HETEROCYCLES TO NOVEL POLYMERS CONTAINING STRAINED FUNCTIONALITY AND CAPACITY FOR POST-POLYMERIZATION MODIFICATION
UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel method for the conversion of Dewar heterocycles to versatile monomers with capacity for post-polymerization chemistry. BACKGROUND: Post-polymerization modifications are crucial in the development of synthetic materials for electronic, biomedical, and feedstock...
Published: 7/19/2023   |   Inventor(s): Hosea Nelson
Keywords(s): Catalysts, Chemical, Chemical Manufacturing & Industrial/Bulk Chemicals, Functional Materials
Category(s): Chemical > Catalysts, Chemical > Polymers, Chemical > Synthesis, Chemical > Industrial & Bulk Chemicals
2020-172 MICROBIAL PRODUCTION OF CANNABINOID PRECURSOR OLIVETOLIC ACID AND ITS ANALOGUES
UCLA researchers in the Department of Chemical & Biomolecular Engineering have developed a novel method for the production of cannabinoid precursor olivetolic acid for the scalable synthesis of cannabinoids. BACKGROUND: Cannabinoids, the chemicals found in the cannabis plant, are widely recognized for their medical applications to alleviate pain....
Published: 7/19/2023   |   Inventor(s): Yi Tang
Keywords(s): Chemical, Hydrocarbons, Pain Treatment, Personal Care / Home Care , Therapeutics & Vaccines
Category(s): Chemical, Therapeutics > CNS and Neurology
2009-554 COMPLEX MIXED LIGAND OPEN FRAMEWORK MATERIALS
Case 2009-554UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel multifarious mixed functionalized metal-organic framework (MOF), which has been demonstrated to be successful in gas storage and separation.BACKGROUNDAdding complexity and increasing the number of building units to crystalline structures usually leads...
Published: 7/19/2023   |   Inventor(s): Omar Yaghi, Christian Doonan, Hexiang Deng
Keywords(s): Chemical, Chemical Manufacturing & Industrial/Bulk Chemicals, Materials
Category(s): Chemical > Industrial & Bulk Chemicals
2011-250 METAL TRIAZOLITES
Case No. 2011-250SUMMARYUCLA researchers in the Department of Chemistry and Biochemistry have developed a novel metal-organic framework (MOF) using triazole ligands that allows for facile modification with a variety of metals, which has unique gas separation and adsorption properties.BACKGROUNDPrevious MOFs with advantageous porosity and stability have...
Published: 7/19/2023   |   Inventor(s): Omar Yaghi, Fernando Uribe Romo, David Britt, Felipe Gandara Barragan
Keywords(s): Chemical, Chemical Manufacturing & Industrial/Bulk Chemicals, Metals
Category(s): Chemical > Synthesis, Chemical > Industrial & Bulk Chemicals, Chemical > Chemical Sensors, Energy & Environment > Energy Storage > Gas Storage
Ligands for Catalyzing Chemical Reactions
Combines Carbene Ligands with Transition Metals to Catalyze Safer and Less Toxic ProductsThese metal complexes supported by carbene ligands are cheaper and more effective alternatives to phosphine ligands for catalyzing chemical reactions. Phosphine ligands attached to transition metals are common catalysts in the pharmaceutical industry and in other...
Published: 6/27/2021   |   Inventor(s): Khalil Abboud, Adam Veige, Mathew Jeletic, Roxy Swails
Keywords(s): Asymmetric, Catalysis, Chemical, Chiral, Enantioselective, Engineering, N-Heterocyclic Carbene, Rhodium
Category(s): Technology Classifications > Engineering > Chemical
1 2