Search Results - -pharmaceutical+composition

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Oxygen as an immunological adjuvant or co-adjuvant to reinforce vaccines and immunotherapies
INV-21019 Background Vaccines are crucial to fight infections, cancer, and autoimmune conditions as they aid in generating immune response before the onset of the disease. Vaccines developed with purified molecules often do not stimulate an effective immune response as compared to the immune response generated against natural infection. Hence, adjuvants...
Published: 9/10/2024   |   Inventor(s): Sidi Bencherif, Thibault Colombani
Keywords(s): Adjuvant, Biomaterials, Co-adjuvant, Oxygen, Vaccines
Category(s): -Pharmaceutical Composition, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery
Cationic Polymers as Co-Drugs for chemotherapeutic Agents
Normal;border-collapse: collapse; } INV-17100 Background There are numerous anticancer chemotherapies available in the market that show cytotoxic effects along with unwanted various side effects. Researchers are trying to induce desired clinical effects at lower concentrations without much success as lowering the drug concentration has led to...
Published: 9/10/2024   |   Inventor(s): Debra Auguste, Daxing Liu
Keywords(s):  
Category(s): -Health, -Pharmaceutical Composition, Technology Classifications > 1. Life Science > Therapeutics, Chemistry, Technology Classifications > 1. Life Science > Drug Delivery
Hygroscopic Molecules Inhibit Collagen Nucleation
INV-20080 Background Collagen serves as the premier, load-bearing molecule in humans and animals, and is one of the major building blocks of bones, skin, muscles, tendons, and ligaments. This abundant protein helps to support and repair damaged tissue. However, the medical community has struggled to fully leverage the power of collagen for use...
Published: 10/15/2024   |   Inventor(s): Jeffrey Paten
Keywords(s): Hygroscopic molecule, Nucleation Inhibitor, Proteoglycan - Glycosaminoglycan - Saccharide, Regeneration, Threshold concentration
Category(s): -Biomedical Materials, -Pharmaceutical Composition, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 1. Life Science > Drug Delivery
Nanopreparation for Co-Delivery of Drugs and siRNA
INV-13004 Background Overexpression of p‑glycoprotein (encoded by MDR1 gene) is often associated with multidrug-resistant cancer. This protein leads to drug resistance by the efflux of chemotherapeutic drugs from the cancerous cells. Small interfering RNA (siRNA), also known as post-transcriptional gene silencer, can suppress the expression of specific...
Published: 9/10/2024   |   Inventor(s): Vladimir Torchilin, Swati Biswas
Keywords(s): Delivery, Drug Delivery, Healthcare Innovation, Medical, Nanomedicine, Nanotechnology, Pharmaceutical Composition, Therapeutic
Category(s): -Nanotechnology, -Nanomedicine, -Pharmaceutical Composition, -Health, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery
Allosteric Modulators of CB1 Cannabinoid Receptors
style-name: Hyperlink;color: #0000FF;text-decoration: underline; } INV-1242 Background Anorexia nervosa (AN) is a major psychiatric eating disorder associated with substantial morbidity and mortality. Its characteristic symptoms include the refusal to maintain minimally normal body weight, an intense fear of becoming fat, and a disturbed perception...
Published: 9/10/2024   |   Inventor(s): Ganeshsingh Thakur, Pushkar Kulkarni
Keywords(s): Cancer, Chemistry, Drug Discovery & Development, Drugs, Therapeutic
Category(s): -Chemistry, -Pharmaceutical Composition, -Health, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Discovery
Allosteric Probes for CB1 Cannabinoid Receptor
esponse. The enhancers of CB1 receptor activity have the potential to treat diseases such as depression, anxiety, multiple sclerosis, and pain. CB1 inhibitors can treat metabolic syndrome as well as drug and alcohol addiction. CB1 inhibitor drugs have been developed for the treatment of type 2 diabetes, weight loss, smoking cessation, and osteoporosis...
Published: 9/10/2024   |   Inventor(s): Ganeshsingh Thakur, Pushkar Kulkarni, Abhijit Kulkarni, Ritesh Tichkule
Keywords(s): Chemistry, Drug Discovery & Development, Health, Pharmaceutical Composition
Category(s): -Pharmaceutical Composition, -Health, -Chemistry, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Discovery