Search Results - -biomedical+materials

11 Results Sort By:
Nanostructured Surfaces - joint with Brown University
INV-14052 Background The attachment of bacteria to surfaces, sometimes referred to as biofilm formation, often occurs in two steps. The first step is the initial attachment of the bacteria to the surface and the second is a cell-to-cell proliferation to form multilayered bacterial clusters. The initial attachment of the bacteria to the surface is...
Published: 10/15/2024   |   Inventor(s): Thomas Webster
Keywords(s):  
Category(s): -Nanotechnology, -Materials, -Biomedical Materials, Technology Classifications > 1. Life Science > Medical Devices
Three Dimensional Auxetic Tiled Composites
New auxetic materials with higher stiffness, strength, and adaptability through large mechanical load and shear https://nu.technologypublisher.com/files/sites/adobestock_988355353.jpeg https://nu.technologypublisher.com/files/sites/mark-saulich-1280x1600.jpg Source: Author Irina/ Adobe Stock # 988355353 INV-21121 Background Auxetic materials...
Published: 10/16/2024   |   Inventor(s): Yaning Li
Keywords(s): Mechanical Metamaterials
Category(s): -Biomedical Materials, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials
Linearization and Translocation of Single Protein Molecules Through Biological Nanopores
INV-21060 Background Nanopore sensing is a promising technology that detects and sequences biomacromolecules without depending on biomolecule modification, labeling, or surface immobilization. Rapid detection of biomacromolecules revolutionizes the field of proteomics and disease diagnosis. Nanopore technology employs nanoscale pores between two electrolytic...
Published: 12/3/2024   |   Inventor(s): Meni Wanunu, Luning Yu, Aleksei Aksimentiev, Behzad Mehrafrooz
Keywords(s): Protein sequencing
Category(s): -Biomedical Materials, -Nanotechnology, -Materials, Technology Classifications > 1. Life Science
PaCyR Sensors for Point of Care Cytokine Monitoring
INV-21038 Background Cytokine storm is a life-threatening uncontrolled elevation of circulating cytokines, which occurs in various inflammatory conditions such as infectious diseases, autoimmune diseases, and cancers. Recently, the COVID-19 pandemic has highlighted the devastating role of a cytokine storm and brought this immune dysregulation response...
Published: 10/18/2024   |   Inventor(s): Heather Clark, Kevin Bardon, Nicole Langlois
Keywords(s):  
Category(s): -Nanotechnology, -Sensors tech, -Biomedical Materials, Technology Classifications > 1. Life Science
A Nanopore Device to Discretely Measure Viral Particle Count and Functional Titer with Single-molecule Resolution
INV-21063 Background An effective response to viral infections relies on rapid, selective, and sensitive detection of viruses. However, it is so difficult to quantify the concentration of packaged viruses in a sample that researchers use indirect metrics to assess concentration such as plaque-forming units (PFU). Other methods for viral analysis such...
Published: 9/10/2024   |   Inventor(s): Sara Rouhanifard, Meni Wanunu
Keywords(s): virus
Category(s): -Biomedical Materials, -Nanotechnology, Technology Classifications > 1. Life Science
Enhanced Radiation Shielding with Conformal Light-weight Nanoparticle-polymer Composite
INV-19025 Background The efficient shielding of ionizing X-ray and gamma radiation is required in medical, nuclear and aerospace industries. High Z elements such as lead, tungsten, bismuth and uranium are often used to attenuate X-ray radiation, where the shielding ability is dependent on the density and mass of the material, leading to heavy shielding...
Published: 9/10/2024   |   Inventor(s): Ming Su
Keywords(s):  
Category(s): -Materials, -Nanotechnology, -Biomedical Materials
Novel bioassay platform for drug and immunotherapy screenings in a personalized format for highly functional cell expansion
INV-19076 Background Immunological screenings for different infections and cancers can yield essential information for developing effect treatments. The efficiency and accuracy of screenings can be improved by choosing efficient matrices and type of assay. Different 3D matrices have been used for immunological screenings. However, due to limited...
Published: 10/15/2024   |   Inventor(s): Giovanni Ugolini, Tania Konry
Keywords(s): Analytical Chemistry, Assays, Detection, Immunological/Autoimmune Disease, Microfluidics
Category(s): -Biomedical Materials, -Chemistry, -Devices, -Equipment, -Cancer
Electromagnetic system to magnetically align discontinuous composite fibers printed from a direct-write 3D printer
INV-16050 Background 3D printing is an additive manufacturing process in which layers of material are deposited according to a three-dimensional computer model. This process has been transformative in prototyping and low-volume part production, but the monolithic (mostly polymer and some metal or ceramic) materials currently used have insufficient...
Published: 9/10/2024   |   Inventor(s): Randall Erb, Andrew Caunter, Ryan Pembroke, Daniel Shores, Amy den Dulk, Scott Goodrich
Keywords(s):  
Category(s): -Biomedical Materials, Technology Classifications > 2. Physical Science > Manufacturing
Hygroscopic Molecules Inhibit Collagen Nucleation
INV-20080 Background Collagen serves as the premier, load-bearing molecule in humans and animals, and is one of the major building blocks of bones, skin, muscles, tendons, and ligaments. This abundant protein helps to support and repair damaged tissue. However, the medical community has struggled to fully leverage the power of collagen for use...
Published: 10/15/2024   |   Inventor(s): Jeffrey Paten
Keywords(s): Hygroscopic molecule, Nucleation Inhibitor, Proteoglycan - Glycosaminoglycan - Saccharide, Regeneration, Threshold concentration
Category(s): -Biomedical Materials, -Pharmaceutical Composition, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 1. Life Science > Drug Delivery
Heterocyclic-Dithol Click Chemistry
INV-18001 Background As exemplified by thiolate-ene “click” chemistry, the unique properties of thiolates enable highly selective reactions. Dithiol-diene reaction partners can template high order structures and are employed (in vitro) in polymer syntheses, in biochemical probes, and to stabilize proteins. Unfortunately, ‑enes react...
Published: 10/15/2024   |   Inventor(s): Jeffrey Agar
Keywords(s):  
Category(s): -Biomedical Materials, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering
1 2