Search Results - regeneration

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Axon Regeneration After Brain or Spinal Cord Injury
The invention is directed to modification of a particular sugar by the enzyme arylsulfatase B (ARSB), which results in axon regeneration. Following traumatic brain or spinal cord injury, glial scars prevent regeneration of axons. Chondroitin sulfate proteoglycans (CSPGs) are major components of glial scars. CSPGs are made of a protein core containing...
Published: 7/25/2024   |   Inventor(s): Yasuhiro Katagiri, Herbert Geller
Keywords(s): AFTER, Arylsulfatase, AXONAL, B, Brain/spinal, CORD, INJURY, NB1JXX, NB1XXX, NBXXXX, NXXXXX, PROMOTES, Regeneration
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Neurology
Hygroscopic Molecules Inhibit Collagen Nucleation
INV-20080 Background Collagen serves as the premier, load-bearing molecule in humans and animals, and is one of the major building blocks of bones, skin, muscles, tendons, and ligaments. This abundant protein helps to support and repair damaged tissue. However, the medical community has struggled to fully leverage the power of collagen for use...
Published: 9/10/2024   |   Inventor(s): Jeffrey Paten
Keywords(s): Hygroscopic molecule, Nucleation Inhibitor, Proteoglycan - Glycosaminoglycan - Saccharide, Regeneration, Threshold concentration
Category(s): -Biomedical Materials, -Pharmaceutical Composition, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 1. Life Science > Drug Delivery
Robust Self-Regeneratable Stiff Living Materials
INV-20116 Background Most biomaterials (e.g. wood, silk) found in nature are formed at ambient conditions and degrade naturally to enable a sustainable ecosystem. In contrast, the production of human-made materials (e.g. cement, plastics) requires high temperatures or harsh chemical treatments, while their non-biodegradability unfavorably affects...
Published: 9/10/2024   |   Inventor(s): Neel Joshi, Anna Duraj-Thatte, Avinash Manjula-Basavanna
Keywords(s): Biomaterials, Biotech, Environment, Living Materials, Manufacturing, Materials, Regeneration
Category(s): Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 2. Physical Science > Manufacturing, Technology Classifications > 1. Life Science > Biotechnology
Bottom-Up Tissue Regeneration Scaffold That Rebuilds Tissue Where It Is Needed
Supports Layered Cell Regrowth, Tissue Repair, Fluid Perfusion and Wound Healing to Replace Injured Bone, Muscle and Skin TissuesThis tissue regeneration platform facilitates the layered regrowth of cells to heal traumatic wounds and other injuries by growing bone, muscle, and skin tissues right where they are needed. Regenerative medicine, in which...
Published: 6/27/2021   |   Inventor(s): Adam Katz
Keywords(s): Angiogenesis, diffusion, Engineering, microfluidics, regeneration, stem cells, Tissue, Tissue Engineering
Category(s): Technology Classifications > Engineering, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Medical Devices
Loading Platform for Three-Dimensional Tissue Engineering Scaffolds
Project ID: D2016-48 IP Status: US Patent #11142739 Technology Summary: Bioreactor systems are a vital cue in the process of 3D tissue engineering and the formation of tissue contracts. Bioreactors capable of stretching three-dimensional (3D) cellular constructs are considered to be good biomimetic models due to their ability to mimic the complexities...
Published: 9/16/2024   |   Inventor(s): Eda Yildirim-Ayan, Gayathri Subramanian, Mostafa Elsaadany
Keywords(s): Cellular Scaffold, Cosmetics, Regeneration, Tissue Engineering
Category(s): Methods