Search Results - drug+discovery+%26+development

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Neuro-Behavioral Assay for Physiological Evaluation of Water-Soluble Anesthetics
Background The development and use of general anesthetics is a key aspect of modern medicine. However, the current reliance on lipid-soluble general anesthetics presents issues, particularly for elderly patients who often have increased adipose tissue and decreased body water. This demographic can respond poorly to lipid-soluble anesthetics, resulting...
Published: 9/10/2024   |   Inventor(s): Gunther Zupanc, David Lehotzky
Keywords(s): Anesthesiology, Assays, Chemotherapy, Drug Discovery & Development, High Throughput Screening
Category(s): Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Drug Discovery
FInD (Foraging Interactive D-prime) - A rapid and general method for efficient and sensitive visual function assessment
21015 Background Vision screening in both clinical and basic science is a critical step that quantifies functional deficits in the visual system. In clinical practice, vision screening is essential for disease diagnosis and monitoring; in basic science, it can quantify sensory or perceptual performance or ensure that research participants meet specific...
Published: 9/10/2024   |   Inventor(s): Peter Bex, Jan Skerswetat
Keywords(s): Adaptive, autism, Detection, Devices, Display, Drug Discovery & Development, Health, Medical, Medical Device, Medical/Health, Mobile devices, Monitoring, Neurological Disease, personalized medicine, Real-Time Implementation, Rehabilitation, Research Tool, Science/Research, Screening Tool, Software and Algorithms
Category(s): -Devices, -Diagnostic Software, Diagnostics
Allosteric Modulators of CB1 Cannabinoid Receptors
style-name: Hyperlink;color: #0000FF;text-decoration: underline; } INV-1242 Background Anorexia nervosa (AN) is a major psychiatric eating disorder associated with substantial morbidity and mortality. Its characteristic symptoms include the refusal to maintain minimally normal body weight, an intense fear of becoming fat, and a disturbed perception...
Published: 9/10/2024   |   Inventor(s): Ganeshsingh Thakur, Pushkar Kulkarni
Keywords(s): Cancer, Chemistry, Drug Discovery & Development, Drugs, Therapeutic
Category(s): -Chemistry, -Pharmaceutical Composition, -Health, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Discovery
Allosteric Probes for CB1 Cannabinoid Receptor
esponse. The enhancers of CB1 receptor activity have the potential to treat diseases such as depression, anxiety, multiple sclerosis, and pain. CB1 inhibitors can treat metabolic syndrome as well as drug and alcohol addiction. CB1 inhibitor drugs have been developed for the treatment of type 2 diabetes, weight loss, smoking cessation, and osteoporosis...
Published: 9/10/2024   |   Inventor(s): Ganeshsingh Thakur, Pushkar Kulkarni, Abhijit Kulkarni, Ritesh Tichkule
Keywords(s): Chemistry, Drug Discovery & Development, Health, Pharmaceutical Composition
Category(s): -Pharmaceutical Composition, -Health, -Chemistry, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Discovery
Hydrogel with Initiator-Tightened Surface
INV- 1007 Background The absence of highly porous, uniformly nanoporous surfaces places limitations on handling, fractionating, extracting, recovering and concentrating aqueous and nonaqueous samples of chemicals and biological substances, both soluble and insoluble. For example, if the surface is not highly porous, then a process that depends on...
Published: 9/10/2024   |   Inventor(s): Roger Giese, Gang Shao
Keywords(s): Analytical Chemistry, Chemistry, Drug Discovery & Development, Research Tool, Screening Tool
Category(s): -Analytical Chemistry, -Chemistry, -Materials, Technology Classifications > 2. Physical Science > Lab tech/equipment
Method and Device for Drug Discovery
INV-1253 Background Historically, natural products and microorganisms have been considered as the major sources of new pharmaceutical compounds. However, in recent years, there has been a dramatic drop in natural-based drug discovery from big pharmaceutical companies. The major challenges are the prevailing paradigm for drug discovery in large pharmaceutical...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s): Analytical Chemistry, Biotech, Drug Discovery & Development, Infectious Disease (including AIDS), Process, Research Tool
Category(s): -Analytical Chemistry, -Health, -Microbiology, Technology Classifications > 2. Physical Science > Lab tech/equipment, Technology Classifications > 1. Life Science > Drug Discovery