Search Results - yang+yang

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THE CHALLENGE Scheduling bandwidth for multiple cell phone users is presently accomplished almost on an arbitrary basis using a predefined algorithms developed to maximize throughput. Since the scheduling frames are updated every 1 ms, this approach has made it virtually impossible to allocate bandwidth in a real-time, on-demand basis, to achieve best...

Published: 4/9/2025 | Inventor(s): Yan Huang, Yiwei Thomas Hou, Yongce Chen

Keywords(s):

Category(s): Technology Classifications > Communication

3DVARIENTVISION: DECODE FUNCTIONAL IMPACTS OF GENETIC VARIANTS BASED ON 3D CHROMATIN

VAlue proposition Deciphering the effects and mechanisms of genetic variants is essential to understand human genetics and further precision medicine. A genetic variant is a permanent change in the nucleotide sequence that makes up a gene, also known as a gene mutation. Mutations can cause diseases or phenotypic changes. Typically, Genome Wide Association...

Published: 4/9/2025 | Inventor(s): Jianrong Wang, Jiaxin Yang

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Category(s): Medical, Biotechnology, Computer Software

Highly Selective and Sensitive Carbon Monoxide Probe

Description This technology is a suite of fluorescent reagents for imaging and quantifying carbon monoxide (CO) in biological samples such as cells, tissue, and blood. Compared to existing methods of CO sensing and quantification for research, these CO detection probes feature CO sensing exclusivity, ultralow background fluorescence, ultrahigh sensitivity,...

Published: 4/8/2025 | Inventor(s): Binghe Wang, Xiaoxiao Yang

Keywords(s):

Category(s): Diagnostic, Research Tool, Assay

Viral Vector-Based Gene Therapy for OPA1 Gene Mutation-Induced Dominant Optic Atrophy (UCLA Case No. 2025-004)

UCLA researchers in the Department of Ophthalmology have developed a viral vector-based gene therapy to restore OPA1 protein levels in patients with OPA1-mutated dominant optic atrophy. The optimized vectors will be delivered intravitreally to patients’ eyes, providing a minimally invasive, effective treatment with reduced side effects. BACKGROUND:...

Published: 3/6/2025 | Inventor(s): Xianjie Yang

Keywords(s): Adeno-associated viruses (AAV), disease model, dominant optic atrophy, Gene Therapy, intravitreal delivery, Lentivirus Viral Vector, mitochondria, mutation, Neuron, OPA1, Ophthalmology, pluripotent stem cell (PSC), retinal ganglion cell

Category(s): Therapeutics > CNS and Neurology, Therapeutics > Gene Therapy And Editing, Therapeutics > Ophthalmology

First in class use of the estrogen receptor-b agonist in treating Angelman syndrome and relevant autism spectrum disorders

Overview Angelman syndrome is a genetic disorder caused by UBE3A gene dysfunction, leading to cognitive impairment, motor coordination issues, and developmental delays. Research suggests that oligodendroglial dysfunction, which affects myelination in the brain, contributes to these conditions. Based on the research, this invention discloses a novel...

Published: 3/17/2025 | Inventor(s): Yu-Wen Huang, Xin Yang

Keywords(s):

Category(s): Genetic Diseases, Therapeutics, Therapy Targets

Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay

Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...

Published: 3/4/2025 | Inventor(s): Yong Zeng, He Yan

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Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics

Silicon-CdTe-Halide Perovskite Triple-Junction Solar Cell

Background Solar energy is one of the most abundant and affordable energies in the world. However, converting solar energy into electricity significantly relies on the power conversion efficiency of the solar cell’s technology. Due to the current limitations of the various materials and physics in the solar cell’s technology, it is a great...

Published: 2/28/2025 | Inventor(s): Feng Yan, Yanfa Yan

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Category(s): Energy & Power, Advanced Materials/Nanotechnology, Physical Science

Silicon-CdTe-Halide Perovskite Triple-Junction Solar Cell

Published: 2/28/2025 | Inventor(s): Feng Yan, Yanfa Yan

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Category(s): Energy & Power, Advanced Materials/Nanotechnology, Physical Science

Low Temperature Synthesis of Chalcogenide Perovskite Nanoparticles

Chalcogenide Perovskite Nanoparticles for Semiconductor and Photovoltaics Manufacturing This technique synthesizes chalcogenide perovskite nanoparticles at relatively low temperatures. Chalcogenides are chemical compounds consisting of at least one chemical element from group VI of the periodic table -- such as sulfur, selenium, and tellurium-- as...

Published: 2/25/2025 | Inventor(s): Charles Hages, Alexander Jess, Ruiquan Yang

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Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials

Intervertebral Disc Repair Using a 3D Porous Hybrid Protein Nanoscaffold

Histological analysis of rat intervertebral disc tissue prior to (left) and post injury (center) compared to 6 weeks post treatment (right). Invention Summary: Degeneration of fibrocartilaginous tissues, such as intervertebral discs (IVD), knee menisci, and other tendon-bone junctions, can lead to debilitating pain. IVD degeneration is the...

Published: 3/25/2025 | Inventor(s): Ki-Bum Lee, Letao Yang, Inbo Han

Keywords(s):

Category(s): Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Biomaterials

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