Search Results - xiaoshi+qian

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Stable Biological Membrane Mimetic For Enhanced Protein Recruitment
Synthetic biological alternative to natural lipids for conjugation with nitrilotriacetic acid (NTA) for enhanced His-tagged protein interaction and long-term stability. Problem: Biomimetic lipid vesicles, such as liposomes, have multiple biotechnology and drug delivery applications as their lipid bilayer innately interacts with natural cell membranes....
Published: 10/16/2023   |   Inventor(s): Virgil Percec, Qi Xiao, Matthew Good
Keywords(s): Bioengineering, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents
2017-704 Materials for Autonomous Tracking, Guiding, Modulating, and Harvesting of Energetic Emissions
Summary: UCLA researchers in the Department of Materials Science and Engineering have developed a novel photo-responsive polymer that can in real-time detect, track, modulate, and harvest incident optical signals and a broad range of energetic emissions at high accuracy and fast response rate. Background: The capability to efficiently and simultaneously...
Published: 12/4/2023   |   Inventor(s): Ximin He, Xiaoshi Qian
Keywords(s): Electronics & Semiconductors, Nanosensor, Other Polymers, Photonics
Category(s): Electrical > Electronics & Semiconductors, Platforms > Drug Delivery > Other Polymers, Optics & Photonics
PI3Kα Inhibitors for the Treatment of Cancer
Application Compounds that inhibit the kinase activity of phospoinostidie 3-kinase (PI3Kα) for the treatment of cancer. Key Benefits Potential therapeutic targeted to pathway without a clinically approved inhibitor. Provides a useful pharmacological probe for research purposes. Market Summary In order to grow, cancer cells must have the...
Published: 7/30/2024   |   Inventor(s): Qi Shi, Thomas Kaiser, Dennis Liotta, James Snyder, Zackery Dentmon, John Diraddo
Keywords(s): Oncology, Small Molecule
Category(s): TechPub Algolia > Therapeutics
Derivatives as CXCR4 Modulators for the Treatment of Inflammation and Metastasis
Application Amide derivatives as chemokine receptor type 4 (CXCR4) modulators for the treatment of inflammation or prevention of cancer cell metastasis. Key Benefits Excellent binding affinity, compared to currently available compounds targeting CXCR4 receptor. Stability in plasma compared to protein/peptide agonists of CXCR4, these amide derivatives...
Published: 10/17/2024   |   Inventor(s): Hyunsuk Shim, Renren Bai, Qi Shi
Keywords(s): Immunology/Inflammation, Oncology, Small Molecule
Category(s): TechPub Algolia > Therapeutics