Search Results - wenliang+wang

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Liquid-phase gas nanotransducers as an ultrasound actuator and imaging reporter
Background Ultrasound imaging and actuation technologies play a critical role in modern medicine, however applications rely heavily on the use of gas-filled agents, such as microbubbles and gas vesicles, which enhance ultrasound contrast and facilitate mechanical effects in biological tissues. The demand for improved imaging resolution, deeper tissue...
Published: 3/12/2026   |   Updated: 3/12/2026   |   Inventor(s): Huiliang Wang, Wenliang Wang
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Medical technology
Non-invasive sono-optogenetic platform for deep brain neural modulation
Background Neuromodulation technologies such as deep brain stimulation and optogenetics have transformed the treatment of neurological disorders by enabling targeted control of dysfunctional neural circuits, yet their clinical adoption is limited by invasive surgical requirements, off-target effects, poor penetration depth, and lack of cell-type specificity....
Published: 3/11/2026   |   Updated: 3/11/2026   |   Inventor(s): Huiliang Wang, Wenliang Wang, Ilia Pyatnitskiy
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Therapeutics
Ultrasound-triggered anesthetic drug delivery for on-demand chronic pain management
A nanoparticle-based ultrasound-responsive drug delivery system for precise, controlled, and targeted therapeutic release This technology uses ultrasound-triggered nanoparticles to deliver local anesthetics precisely and safely for pain management, reducing side effects and opioid risks, with potential for targeted delivery of other drugs in cancer,...
Published: 3/10/2026   |   Updated: 2/17/2026   |   Inventor(s): Huiliang Wang, Weilong He, Xi Shi, George Bittner, Cathy Yang, Yanxing Wang, Wenliang Wang, Pengyu Ren
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Updated: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Low-Cost High-Performance 3D LiDAR Imaging System
Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...
Published: 12/16/2025   |   Updated: 12/15/2025   |   Inventor(s): Wen Li, Suk Kyoung Lee, Blessed Oguh, Sulaiman Abubakar
Keywords(s):  
Category(s): Technology Category > Automotive & Transportation, Technology Category > Physical Sciences, Technology Category > Image Analysis (Cameras & Software), Technology Category > Revolutionizing Mobility
Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.
Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...
Published: 5/9/2025   |   Updated: 4/24/2025   |   Inventor(s): Suraj Sable, James Posey, Wen Li, Allison Kline
Keywords(s):  
Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 10/21/2025   |   Updated: 9/13/2024   |   Inventor(s): Wen Li, Hasan Banna, James Siegenthaler, Mohammad Kafi Kangi, Tumi Olason
Keywords(s):  
Category(s): Agriculture, Analytical Instruments, Environment, Test and Measurement
RECAST as an enhanced gene delivery system
Background/problem Gene therapy, a promising tool to explore pathogenesis and a powerful weapon to treat diseases at the genomic level, has been making strides in recent years. It has found use in various applications, from cell therapeutics to treating inherited, and neurodegenerative diseases. However, the current methods of gene (“therapy”,...
Published: 1/13/2026   |   Updated: 7/25/2024   |   Inventor(s): Huiliang Wang, Wenliang Wang, Aaron Tasset
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Formulation
Ultrasound-programmable nanoparticles for targeted drug release
Background/problem Ideally, a drug meant to accurately target specific tissues or cells involved in a disease will do so and achieve an optimal dose and treatment duration. These will yield the intended cellular and physiological response without undue off-target and side effects. And yet, we live with the reality and risks of side effects. Novel...
Published: 1/13/2026   |   Updated: 6/25/2024   |   Inventor(s): Wenliang Wang, Huiliang Wang, Yanshu Shi, Banglin Chen
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Biomaterials
Sono-optogenetics: A non-invasive optogenetic platform
Problem Optogenetics is the light-dependent control of genetically modified neurons. Neuronal cells that express microbial opsins can transport ions in a light-gated process. Optogenetics has been used to treat disorders including vision loss in humans. Animal studies indicate that optogenetic therapies have applications in neurological disorders including...
Published: 1/13/2026   |   Updated: 2/2/2024   |   Inventor(s): Huiliang Wang, Wenliang Wang, Kai Wing Tang, Guosong Hong, Xiang Wu
Keywords(s):  
Category(s): Life sciences > Therapeutics
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