Search Results - wenliang+wang

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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Low-Cost High-Performance 3D LiDAR Imaging System
Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...
Published: 12/16/2025   |   Inventor(s): Wen Li, Suk Kyoung Lee, Blessed Oguh, Sulaiman Abubakar
Keywords(s):  
Category(s): Technology Category > Automotive & Transportation, Technology Category > Physical Sciences, Technology Category > Image Analysis (Cameras & Software), Technology Category > Revolutionizing Mobility
Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.
Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...
Published: 5/9/2025   |   Inventor(s): Suraj Sable, James Posey, Wen Li, Allison Kline
Keywords(s):  
Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 10/21/2025   |   Inventor(s): Wen Li, Hasan Banna, James Siegenthaler, Mohammad Kafi Kangi, Tumi Olason
Keywords(s):  
Category(s): Agriculture, Analytical Instruments, Environment, Test and Measurement
RECAST as an enhanced gene delivery system
Background/problem Gene therapy, a promising tool to explore pathogenesis and a powerful weapon to treat diseases at the genomic level, has been making strides in recent years. It has found use in various applications, from cell therapeutics to treating inherited, and neurodegenerative diseases. However, the current methods of gene (“therapy”,...
Published: 11/25/2025   |   Inventor(s): Huiliang Wang, Wenliang Wang, Aaron Tasset
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Formulation
Ultrasound-programmable nanoparticles for targeted drug release
Background/problem Ideally, a drug meant to accurately target specific tissues or cells involved in a disease will do so and achieve an optimal dose and treatment duration. These will yield the intended cellular and physiological response without undue off-target and side effects. And yet, we live with the reality and risks of side effects. Novel...
Published: 1/8/2026   |   Inventor(s): Wenliang Wang, Huiliang Wang, Yanshu Shi, Banglin Chen
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Biomaterials
Sono-optogenetics: A non-invasive optogenetic platform
Problem Optogenetics is the light-dependent control of genetically modified neurons. Neuronal cells that express microbial opsins can transport ions in a light-gated process. Optogenetics has been used to treat disorders including vision loss in humans. Animal studies indicate that optogenetic therapies have applications in neurological disorders including...
Published: 11/25/2025   |   Inventor(s): Huiliang Wang, Wenliang Wang, Kai Wing Tang, Guosong Hong, Xiang Wu
Keywords(s):  
Category(s): Life sciences > Therapeutics
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/6/2026   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Implantable Neural Microelectrodes and Fabrication Method
Executive SummaryMicroelectrodes have become vital in the current-day attempt to map and understand the human brain, as well as delivering unique therapeutic solutions. These microelectrodes are able to work as biosensors, picking up changes in potential and electrophysiology. In particular, extracellular sensors can record data on neurotransmitter...
Published: 2/17/2023   |   Inventor(s): Wen Li, Yue Guo, Thomas Schuelke, Michael Becker, Robert Rechenberg, Cory Rusinek
Keywords(s):  
Category(s): Advanced Materials, Biotechnology, Devices
Flexible Hybrid Diamond Biosensor
Executive SummaryA unique fabrication method creates a new flexible and implantable thin film sensor for the biochemical, medical and neural engineering fields. This diamond-polymer hybrid demonstrates improved biocompatibility, durability and chemical sensing capabilities. Description of TechnologyThe rigidness and attachment incompatibilities of...
Published: 6/8/2021   |   Inventor(s): Wen Li, Bin Fan, Michael Becker, Robert Rechenberg
Keywords(s):  
Category(s): Advanced Materials, Devices
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