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Search Results - vaccines
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Capless and Tailless Therapeutic Exogenous mRNA for Vaccine Development
Opportunity The approval and distribution of messenger RNA (mRNA)
vaccines
to successfully control the SARS-CoV-2 pandemic in 2021 exposed a major market for vaccine innovation and mRNA-based therapies. The mRNA used for treatment or vaccination is produced with a protecting 5’ cap and a 3’ poly-A tail at each end of the mRNA molecule....
Published: 6/12/2024
|
Inventor(s):
Brian Fouty
,
Victor Solodushko
Keywords(s):
Category(s):
All Technologies
,
Antibody
,
Therapeutics
,
Vaccines
,
Gene Therapy and Delivery
COVID-19 vaccination training video
Technology Overview This training video provides comprehensive training on COVID-19 vaccinations and key aspects of a COVID-19 mass immunization program. It is a one-stop shop resource to train participants to be able to provide safe and effective COVID-19 vaccinations. This training is being used by 58 counties in California through the State of...
Published: 9/27/2023
|
Inventor(s):
Andrea Dayot
,
Marcel Curlin
Keywords(s):
COVID-19 Technologies
,
Education & Training - Clinical
,
Education & Training - Other
Category(s):
Vaccines
,
Education & Training
Live recombinant Measles-M2 vaccine induces broad-spectrum protective immunity against influenza viruses
Summary The invention relates to a live attenuated recombinant measles virus expressing influenza A virus antigens (M2 and NP or M1 and M2) and to its use in the elicitation of immunity, in particular protective immunity and advantageously broad-spectrum protective immunity against influenza A virus. The influenza A virus is selected among epidemic...
Published: 2/12/2021
|
Inventor(s):
Keywords(s):
VACCINE
Category(s):
Vaccines
RNA virus attenuation by alteration of mutational robustness and sequence space
Summary RNA viruses pose serious threats to human health. Their success relies on their capacity to generate genetic variability and, consequently, on their adaptive potential. We describe a strategy to attenuate RNA viruses by altering their evolutionary potential. As an example, we rationally altered the genome of influenza A virus to redirect its...
Published: 2/12/2021
|
Inventor(s):
Keywords(s):
VACCINE
Category(s):
Vaccines
New vaccine delivery system : multimeric viral nanoparticles and yeast as vaccine production, delivery and auto-adjuvanted strategy
Summary Efficient antigen delivery is essential to success in vaccinology. Antigens immunogenicity can be enhanced or weakened by inappropriate vaccine design. Multimerization enhances antigen immunogenicity and whole recombinant yeast-based
vaccines
elicit highly efficient immune responses. We have developed a new vaccine platform, which combines...
Published: 2/12/2021
|
Inventor(s):
Keywords(s):
VACCINE
Category(s):
Vaccines
Gonorrhea Subunit Vaccine
Background of Invention Each year witnesses roughly 78 million new gonorrhea infections [etiologic agent Neisseria gonorrhoeae (Ng)] worldwide. While often asymptomatic (particularly in females), untreated infection can lead to pelvic inflammatory disease, ectopic pregnancy, infertility, and increased transmission/acquisition of HIV. Although antimicrobials...
Published: 4/6/2022
|
Inventor(s):
Aleksandra Sikora
,
Ryszard Zielke
,
Ann Jerse
Keywords(s):
Gonorrhea
,
vaccine
Category(s):
Vaccines
Reorganization of Arenavirus Genome for Development of Novel Arenavirus Live-Attenuated
Vaccines
(LAV)
Disclosed are compositions and methods related to recombinant arenaviruses and their use in
vaccines
for the treatment or prevention of an arenavirus infection.
Published: 10/28/2024
|
Inventor(s):
Juan Carlos De La Torre
,
Luis Martinez-Sobrido
,
Masaharu Iwasaki
,
Beatrice Cubitt
Keywords(s):
Category(s):
Vaccines
Mycobacterium Bovis Vaccine to Prevent Bovine Tuberculosis
Technology Description Oregon State University is seeking a licensee or collaborative research partner to develop a Mycobacterium bovis vaccine for the prevention of bovine tuberculosis. The vaccine is based on the discovery of bacterial surface antigens expressed during an infection. These surface antigens are present on bacteria transmitted from an...
Published: 1/16/2023
|
Inventor(s):
Luiz Bermudez
Keywords(s):
Agriculture
,
bovine
,
Mycobacterium
,
tuberculosis
,
vaccine
Category(s):
Vaccines
Long-Lasting and Self-Sustaining Cell Therapy System
SummaryCurrent T-cell therapies rely on the successful transplant and survival of infused, therapeutic cells in a patient. The efficacy of a cell therapy is limited by the extent of cell survival after adoptive cell transfer (ACT) and by the stability of the engraftment. Poor engraftment of transplanted cells results in loss of therapeutic efficacy,...
Published: 2/7/2023
|
Inventor(s):
Keywords(s):
Cardiovascular
,
Inflammatory/Immune/Wound Repair
,
Oncology
Category(s):
Therapeutics
,
Vaccines
Peptide Inhibitors of Gonorrhoeae
Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...
Published: 12/23/2021
|
Inventor(s):
Aleksandra Sikora
,
Konstantin Korotkov
Keywords(s):
Antibiotics
,
Antimicrobial
,
Drug
,
Drug Development
,
Gonorrhea
,
Inhibitor
,
Microbiology
,
Peptide
,
Therapeutic
Category(s):
Therapeutics
,
Vaccines
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