Search Results - luis+martinez-sobrido

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Human Monoclonal Antibodies for Prevention and Treatment of Influenza Virus Infections
Background Seasonal influenza, also referred to as influenza or flu, is a contagious respiratory viral illness. Influenza infection varies in severity, causing asymptomatic infection to fatal disease, particularly for high-risk patient populations such as the elderly (over 65 years of age), young children (under five years of age), pregnant women,...
Published: 10/28/2024   |   Inventor(s): James Kobie, Luis Martinez-Sobrido, Michael Piepenbrink, Aitor Nogales-Gonzalez
Keywords(s):  
Category(s): Therapeutic
Human Monoclonal Antibodies for Prevention and Treatment of Influenza Virus Infections
Background Seasonal influenza, also referred to as influenza or flu, is a contagious respiratory viral illness. Influenza infection varies in severity, causing asymptomatic infection to fatal disease, particularly for high-risk patient populations such as the elderly (over 65 years of age), young children (under five years of age), pregnant women,...
Published: 10/28/2024   |   Inventor(s): James Kobie, Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Michael Piepenbrink
Keywords(s):  
Category(s): Therapeutic
Glucuronoxylomannan (GXM) for Use in Drug Delivery to Central Nervous System
Polysaccharide Related to the Cause of Fungal Meningitis Temporarily Breaks Down Blood-Brain Barrier, Suggesting Effective Delivery of Therapeutics This major capsular polysaccharide of the fungus Cryptococcus neoformans (C. neoformans), glucuronoxylomannan (GXM), can be administered with or attached to a drug to temporarily enable it to cross the...
Published: 2/22/2024   |   Inventor(s): Luis Martinez
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Drug Delivery, Technology Classifications > Human Health Care > Others
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
Reorganization of Arenavirus Genome for Development of Novel Arenavirus Live-Attenuated Vaccines (LAV)
Disclosed are compositions and methods related to recombinant arenaviruses and their use in vaccines for the treatment or prevention of an arenavirus infection.
Published: 10/28/2024   |   Inventor(s): Juan Carlos De La Torre, Luis Martinez-Sobrido, Masaharu Iwasaki, Beatrice Cubitt
Keywords(s):  
Category(s): Vaccines
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology
Development of Arenavirus Vaccines through Codon Deoptimization
A novel strategy for developing live-attenuated arenavirus vaccines. Problem Solved by the TechnologyArenaviruses have a significant impact on public health and pose a credible threat to biodefense.There are four arenaviruses that cause severe hemorrhagic fever in humans (Lassa virus, endemic to Africa; and Machupo, Junin, and Guanarito viruses endemic...
Published: 10/28/2024   |   Inventor(s): Luis Martinez-Sobrido, Juan Carlos De La Torre
Keywords(s):  
Category(s): Vaccines