Search Results - aleksandra+sikora

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Gonorrhea Subunit Vaccine
Background of Invention Each year witnesses roughly 78 million new gonorrhea infections [etiologic agent Neisseria gonorrhoeae (Ng)] worldwide. While often asymptomatic (particularly in females), untreated infection can lead to pelvic inflammatory disease, ectopic pregnancy, infertility, and increased transmission/acquisition of HIV. Although antimicrobials...
Published: 4/6/2022   |   Inventor(s): Aleksandra Sikora, Ryszard Zielke, Ann Jerse
Keywords(s): Gonorrhea, vaccine
Category(s): Vaccines
Peptide Inhibitors of Gonorrhoeae
Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...
Published: 12/23/2021   |   Inventor(s): Aleksandra Sikora, Konstantin Korotkov
Keywords(s): Antibiotics, Antimicrobial, Drug, Drug Development, Gonorrhea, Inhibitor, Microbiology, Peptide, Therapeutic
Category(s): Therapeutics, Vaccines