Search Results - antibody

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Capless and Tailless Therapeutic Exogenous mRNA for Vaccine Development
Opportunity The approval and distribution of messenger RNA (mRNA) vaccines to successfully control the SARS-CoV-2 pandemic in 2021 exposed a major market for vaccine innovation and mRNA-based therapies. The mRNA used for treatment or vaccination is produced with a protecting 5’ cap and a 3’ poly-A tail at each end of the mRNA molecule....
Published: 6/12/2024   |   Inventor(s): Brian Fouty, Victor Solodushko
Keywords(s):  
Category(s): All Technologies, Antibody, Therapeutics, Vaccines, Gene Therapy and Delivery
Antibody specific for PKG-1alpha nitration
Scientists at AU identified that nitration of PKG-1α in tyrosine 247 attenuates the catalytic activity of PKG-1 α, which plays a critical role in the development of vascular dysfunction in pulmonary hypertension and other vascular pathologies. The inventors developed the humanized monoclonal antibody or antigen-binding fragment for detecting...
Published: 3/31/2022   |   Inventor(s): Stephen Black
Keywords(s):  
Category(s): Diagnostics, Therapeutics, Antibody